Issue 92, 2012
From the journal:

Chemical Communications

Visualization of the intracellular location and stability of DNA origami with a label-free fluorescent probe†‡

Xibo Shen,a   Qiao Jiang,b   Jinye Wang,b   Luru Dai,b   Guozhang Zou,b   Zhen-Gang Wang,b   Wei-Qiang Chen,c   Wei Jiang*a  and  Baoquan Ding*b  

* Corresponding authors

a School of Chemistry and Chemical Engineering, Shandong University, Jinan 250100, P. R. China
E-mail: wjiang@sdu.edu.cn
Fax: +86 531 8856446
Tel: +86 531 88363888

b National Center for Nanoscience and Technology, 11 Bei Yi Tiao, ZhongGuanCun, Beijing 100190, P. R. China
E-mail: dingbq@nanoctr.cn
Fax: +86 10 62656765
Tel: +86 10 82545636

c Institute of Modern Physics, Chinese Academy of Sciences, Lanzhou 730000, P. R. China

Abstract

We report a label-free fluorescent strategy to study the distribution and stability of DNA origami nanostructures in live, cellular systems, using carbazole-based biscyanine as a probe molecule which has the characteristic property of restriction of intramolecular rotation (RIR) induced emission.

Graphical abstract: Visualization of the intracellular location and stability of DNA origami with a label-free fluorescent probe

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Supplementary files

Article information

DOI
https://doi.org/10.1039/C2CC36185J
Article type
Communication
Submitted
25 Aug 2012
Accepted
27 Sep 2012
First published
28 Sep 2012

Chem. Commun., 2012,48, 11301-11303

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Visualization of the intracellular location and stability of DNA origami with a label-free fluorescent probe

X. Shen, Q. Jiang, J. Wang, L. Dai, G. Zou, Z. Wang, W. Chen, W. Jiang and B. Ding, Chem. Commun., 2012, 48, 11301 DOI: 10.1039/C2CC36185J

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