A novel and efficient method for the regioselective bromination of pyrrolo[1,2-a]quinoxaline using tetrabutylammonium tribromide was developed. A series of highly selective C3-brominated or C1, C3-dibrominated products were obtained in good yields.
The synthesis of pyrrole-fused heterocycles is demonstrated using the first biomass-derived glucose-mediated one-pot multicomponent nitro reductive cyclization method.
In this review, we have summarized the recent progress in two-component and three-component synthetic approaches for the eco-friendly construction of functionalised and fused quinoxaline frameworks.
Selective arylation of pyrrolo[1,2-a]quinoxaline C–H bonds with aryl bromides in the absence of a silver additive is developed.
A chemoselective reduction of a nitro group in the presence of an aldehyde or ester group integrated with another synthetic transformation leading to the expedient synthesis of important heterocycles is the subject of this current investigation.