Jin Zhang, Hui Zhao, Guangchen Li, Xinhao Zhu, Linqin Shang, Yang He, Xin Liu, Yangmin Ma and Michal Szostak
Org. Biomol. Chem., 2022,20, 5981-5988
From themed collection:
New Talent
Abstract
We present a general strategy for activation of N–C(S) thioamide bonds by ground-state-destabilization in the context of a full study on transamidation of thioamides with nucleophilic amines.
Jim Secka, Arpan Pal, Francis A. Acquah, Blaine H. M. Mooers, Anand B. Karki, Dania Mahjoub, Mohamed K. Fakhr, David R. Wallace, Takuya Okada, Naoki Toyooka, Adama Kuta, Naga Koduri, Deacon Herndon, Kenneth P. Roberts, Zhiguo Wang, Bethany Hileman, Nisha Rajagopal and Syed R. Hussaini
RSC Adv., 2022,12, 19431-19444
Abstract
This paper describes the synthesis of enamino carbonyl compounds by the copper(I)-catalyzed coupling of acceptor-substituted diazo compounds and tertiary thioamides.
Weikang Li, Zhe Chen, Chuanyi Xiong, Zhenjie Yang, Ning Wang, Peifeng Su, Yaru Jing, Haihua Huang and Zhuofeng Ke
Org. Chem. Front., 2025,12, 6423-6432
Abstract
A catalyst-free protocol for the reductive desulfurization of thioamides using ammonia borane (AB) has been successfully developed.
Kristen E. Fiore, Martijn J. Patist, Sam Giannakoulias, Cheng-Hsin Huang, Hitesh Verma, Bhavesh Khatri, Richard P. Cheng, Jayanta Chatterjee and E. James Petersson
RSC Chem. Biol., 2022,3, 582-591
From themed collection:
Synthesis and chemical biology of macrocycles
Abstract
NMR studies of macrocyclic β-hairpin model systems demonstrate that thioamides can be tolerated at both hydrogen bond donor and hydrogen bond acceptor positions.
Yu Gao, Fang Chai and Chengwei Liu
New J. Chem., 2024,48, 19496-19500
Abstract
Hydroxylamine hydrochloride-catalyzed transamidation of primary thioamides with primary and secondary amines via C(S)–N bond cleavage and formation has been reported.