Comparison between conventional, grinding, and microwave synthesis of methylpyrazoles as VEGFR-2/HSP90 dual inhibitors

Ebtehal M. Husseiny, Rana M. Abdelnaby, Najla Altwaijry, Asmaa Saleh and Kurls E. Anwer

Future Medicinal Chemistry, 2025, 17, 899
DOI: 10.1080/17568919.2025.2485866

Design, synthesis, and in silico insights of novel N’-(2-oxoindolin-3-ylidene)piperidine-4-carbohydrazide derivatives as VEGFR-2 inhibitors

Wagdy M. Eldehna, Youmna A. Habib, Abeer E. Mahmoud, Mohamed F. Barghash, Zainab M. Elsayed, Ahmed E. Elsawi, Raed M. Maklad, Mahmoud Rashed, Amira Khalil, Sherif F. Hammad, Mamdouh M. Ali and Ahmed M. El Kerdawy

Bioorganic Chemistry, 2024, 153, 107829
DOI: 10.1016/j.bioorg.2024.107829

Comparative Study of Conventional, Grinding, and Microwave‐Assisted Synthesis of Aminopyrazolones and Diaminopyrazoles: Exploring the Antitumor Activity, Dual CDK‐2/CA IX Inhibition Potential, and Apoptosis Induction

Kurls E. Anwer, Nehad M. El‐Dydamony, Asmaa Saleh, Najla Altwaijry and Ebtehal M. Husseiny

Drug Development Research, 2025, 86
DOI: 10.1002/ddr.70139

Design, synthesis, radiolabeling, and mechanistic insights of hydrazinyl imidazolones as broad spectrum antitumor agents with potential carbonic anhydrase inhibition: In vitro, in vivo, and in silico studies

Ebtehal M. Husseiny, Marwa T. Sarg, Yasmin S. Sheta, Manal M. Sayed and Fatma G. Abdulrahman

European Journal of Medicinal Chemistry, 2025, 298, 118049
DOI: 10.1016/j.ejmech.2025.118049

Insecticidal effect of new synthesized chalcone derivatives on Caribbean fruit fly, Anastrepha suspensa

Sümeyye Yücetepe, Bedia Koçyiğit-Kaymakçıoğlu, Xiangbing Yang, Nurhayat Tabanca and Fatih Tok

Zeitschrift für Naturforschung C, 2024, 79, 267
DOI: 10.1515/znc-2024-0005

Chemical composition’s effect on Solanum nigrum Linn.’s antioxidant capacity and erythrocyte protection: Bioactive components and molecular docking analysis

Abdelatif Aouadi, Djamila Hamada Saoud, Abdelkrim Rebiai, Mona H. Ibrahim, Mohammed Messaoudi, Khaoula Alia, Halima Zidane, Ayomide Victor Atoki and Fatma Mohamed Abd El-Mordy

Open Life Sciences, 2024, 19
DOI: 10.1515/biol-2022-0944

Design, synthesis, and mechanistic insight of novel imidazolones as potential EGFR inhibitors and apoptosis inducers

Fatma G. Abdulrahman, Hamada S. Abulkhair, Hoda S. El Saeed, Nehad M. El-Dydamony and Ebtehal M. Husseiny

Bioorganic Chemistry, 2024, 144, 107105
DOI: 10.1016/j.bioorg.2024.107105

Thunbergia’s Flowers Secondary Metabolites a Natural Armor Against Kidney Damage by Diclofenac

Fatma Sayed Abdel-Aal Farag, Fatma Mohamed Abd El-Mordy, Mona H. Ibrahim, Enas S. Gad, Rania H. M. Soliman and Hend M. Anwar

Cell Biochem Biophys, 2024, 82, 2813
DOI: 10.1007/s12013-024-01397-4

Novel imidazolone derivatives as potential dual inhibitors of checkpoint kinases 1 and 2: Design, synthesis, cytotoxicity evaluation, and mechanistic insights

Yasmin S. Sheta, Marwa T. Sarg, Fatma G. Abdulrahman, Eman S. Nossier and Ebtehal M. Husseiny

Bioorganic Chemistry, 2024, 149, 107471
DOI: 10.1016/j.bioorg.2024.107471