Rapid and green quantification of phloridzin and trilobatin in Lithocarpus litseifolius (Hance) Chun (sweet tea) using an online pressurized liquid extraction high-performance liquid chromatography at equal absorption wavelength method

Zhengming Qian, Qinggui Lei, Dan Tang, Guoying Tan, Qi Huang, Fucai Zhou and Wenhao Wang

Anal. Methods, 2024, 16, 2513
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Inhibition of α-glucosidase activity and intestinal glucose transport to assess the in vivo anti-hyperglycemic potential of dodecyl-acylated phlorizin and polydatin derivatives

Zhengming Xu, Kseniya Hileuskaya, Aliaksandr Kraskouski, Yujiao Yang, Zhe Huang and Zhengang Zhao

Food Funct., 2024, 15, 4785
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Effects of natural dihydrochalcones in sweet tea (Lithocarpus polystachyus) on diabetes: a systematical review and meta-analysis of animal studies

Xue-Min Chen, Wei-Qi Yang, Xue Wang, Chong Chen, Zheng-Ming Qian, Shu-Mei Wang and Dan Tang

Food Funct., 2022, 13, 5899
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A multimodal caffeic acid-derived alkyl-amide antidiabetic agent: targeting α-glucosidase, α-amylase, oxidative stress, and protein glycation

Karthika Kannan and Sushabhan Sadhukhan

RSC Adv., 2025, 15, 41833
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In vitro inhibitory effect of five natural sweeteners on α-glucosidase and α-amylase

Jiequn Jiang, Heliang Fan, Jie Zhou, Jingkai Qin, Zhongyi Qin, Mei Chen, Yuanyuan Shen and Xiaoling Liu

Food Funct., 2024, 15, 2234
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A novel electrochemical sensor based on gold nanobipyramids and poly-l-cysteine for the sensitive determination of trilobatin

Xue Mei, Wenchang Wang, Qingyi Li, Minxian Wu, Liyin Bu and Zhidong Chen

Analyst, 2023, 148, 2335
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Synthesis and pharmacological activities of Schiff bases with some transition metal complexes: a review

Kibrom Mezgebe and Endale Mulugeta

Med Chem Res, 2024, 33, 439
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Effects of 6-Shogaol on Glucose Uptake and Intestinal Barrier Integrity in Caco-2 Cells

Wenya Jiao, Yaxin Sang, Xianghong Wang and Shuo Wang

Foods, 2023, 12, 503
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Inhibitory mechanism of chrysin and diosmetin to α-glucosidase: insights from kinetics, multispectroscopy and molecular docking investigations

Yuqing Zhang, Yaping Li, Yuhan Zhai, Xing Zhao, Mingxing Lv, Shaoxuan Yu, Haifang Xiao and Yuanda Song

Journal of Biomolecular Structure and Dynamics, 2025, 43, 8334
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Exogenous Trilobatin Enhances Flavonoid Content in Purple Rice Grains and Affects the Flavonoid Biosynthesis Pathway

Qiangqiang Xiong, Han Wu, Runnan Wang, Siqi Tang and Haihua Luo

Plants, 2024, 13, 3389
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Trilobatin regulates glucose metabolism by ameliorating oxidative stress and insulin resistance in vivo and in vitro

Ming He, Yuqing Zhang, Yuhan Zhai, Yaping Li, Guorui Yang, Shaoxuan Yu, Haifang Xiao and Yuanda Song

Journal of Pharmacy and Pharmacology, 2025, 77, 236
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Structural characterization, physicochemical properties and hypoglycemic activity of sulfated polysaccharides from Porphyra yezoensis

Cong Teng, Suling Li, Lujing Xu, Kaiyang Ma, Yifei Lu, Jin Feng, Zhi Chai, Xindi Hu, Wei Zhou and Ying Li

Food Bioscience, 2024, 62, 105163
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Trilobatin ameliorates HFD/STZ-induced glycolipid metabolism disorders through AMPK-mediated pathways

Yu-te Zhong, Qiong Shen, Yu-ting Yang, Ruo-bing Zhang, Li-chun Zhao and Wei Li

Journal of Functional Foods, 2023, 103, 105478
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Biological importance and therapeutic potential of Trilobatin in the management of human disorders and associated secondary complications

Dinesh Kumar Patel

Pharmacological Research - Modern Chinese Medicine, 2022, 5, 100185
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Insights into novel α-glucosidase (α-GLU) inhibitory peptides from sturgeon fish muscle protein based on in-silico and in-vitro investigation

Zhiqing Liu, Xiaoyan Kuang, Lingfeng Xu, Xiaodan Fan and Wenyong Lou

Food Wellness, 2025, 1, 100010
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Studies on the inhibition of α-glucosidase by biflavonoids and their interaction mechanisms

Huan Li, Jichen Yang, Mengfan Wang, Xiangzhao Ma and Xin Peng

Food Chemistry, 2023, 420, 136113
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Natural functional sweet-tasting molecules from food-medicine plants: an updated review of their sources and classifications, sensory evaluation, mechanism of sweet taste transduction and safety

Rong Li, Kangmeng Sun, Jiayi Liang, Xinyu Luan, Xinyuan Sun, Peigen Xiao and Chunnian He

Trends in Food Science & Technology, 2026, 168, 105494
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The interaction mechanism of tepotinib and α-glucosidase: A prelude to control type 2 diabetes mellitus

Ying Wang, Lingyan Xu, Qin Tao, Bin Zhou and Zhenhong Zhu

Arabian Journal of Chemistry, 2024, 17, 105802
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Blood glucose-lowering activity of protocatechuic acid is mediated by inhibiting α-glucosidase

Huafang Ding, Shouhe Huang, Chui Yiu Chook, Erika Kwek, Chi Yan, Kaying Ma, Jianhui Liu, Hanyue Zhu and Zhenyu Chen

Food Science and Human Wellness, 2024, 13, 1212
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Effect of polysaccharides on the inhibition and binding ability of hesperetin-copper(II) complex on α-glucosidase

Xi Peng, Yushi Wei, Yijing Liao, Xing Hu, Deming Gong and Guowen Zhang

Colloids and Surfaces B: Biointerfaces, 2025, 250, 114564
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The structural characteristics of hydroxyl and galloyl groups determine the inhibitory activity of α-amylase in four catechin monomers

Rourou Wen, Xianghua Chai, Pingping Wang, Kegang Wu, Xuejuan Duan, Jiasi Chen and Xiumei Li

LWT, 2025, 222, 117624
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Investigation on the interaction mechanism of trilobatin with pepsin and trypsin by multi-spectroscopic and molecular docking methods

Yaping Li, Yuqing Zhang, Yuhan Zhai, Guorui Yang, Haifang Xiao and Yuanda Song

Journal of Molecular Liquids, 2024, 415, 126424
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Developing Lipase Inhibitor as a Novel Approach to Address the Rice Bran Rancidity Issue─A Critical Review

Qingyun Li, Kunlun Liu, Gongli Cai, Xi Yang and Jacky Chi Ki Ngo

J. Agric. Food Chem., 2024, 72, 3277
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Inhibition of Hawthorn Leaf Condensed Tannins on α-Glucosidase and Nonenzymatic Glycosylation: Molecular Mechanisms of Action

Shan-Mei Zeng, Wu-Mei Jiang, Yan Lin, Ze-Lin Liao, Jia-Yi Liang, Ze-Dan Yang, Wen-Jing Wu, Jia-Yi Luo and Wei-Ming Chai

J. Agric. Food Chem., 2026
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Widely Targeted Metabolomic and Network Pharmacology Analyses of Active Compounds Enriched from Ethanolic Extract of Oudemansiella raphanipes

Zhi Wu, Jin Zhao, Shuang Zhu, Mengxing Chen, Dan Wu, Yiyou Wu, Junbin Lin, Renyun Miao, Rencai Feng, Xiang Li, Bingcheng Gan and Tao Wang

Foods, 2025, 14, 2820
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Influence of fruit maturation on phytochemical profiles and antidiabetic potential in peppers

Mahvash Afshari, Morteza Sadeghi and Sanghyeob Lee

Food Bioscience, 2025, 68, 106645
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GWAS provides new insights into the genetic mechanisms of phytochemicals production and red skin colour in apple

Satish Kumar, Claire Molloy, Martin Hunt, Cecilia Hong Deng, Claudia Wiedow, Christelle Andre, Andrew Dare and Tony McGhie

Horticulture Research, 2022, 9
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Acetylation of the polysaccharide from Houttuynia cordata rhizome and their α‐glucosidase inhibition mechanism

Mengyao He, Shuxin Tang, Tingting Xu, Yanan Yuan, Ting Wu, Siyi Pan and Xiaoyun Xu

Journal of Food Science, 2024, 89, 2672
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Optimization of Extraction Process of Polysaccharides MAP-2 from Opuntia Milpa Alta by Response Surface Methodology and Evaluation of Its Potential as α-Glucosidase Inhibitor

Yan Yang, Maohui Yang, Xin Zhou and Huaguo Chen

Foods, 2022, 11, 3530
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Avicularin is a minor aldose reductase inhibitor in defatted seeds of Oenothera biennis L.: Screening, inhibitory kinetics, and interaction mechanism

Yueyao Huang, Zhaoyang Wu, Lei Ma, Xue Han, Hongyuan Yan, Soon Sung Lim and Zhiqiang Wang

Food Chemistry, 2025, 473, 143100
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Chemical profile of phenolic extracts from rapeseed meal and inhibitory effects on α-glucosidase: UPLC-MS/MS analysis, multispectral approaches, molecular simulation and ADMET analysis

Huihui Liu, Ziliang Li, Xiaoyang Xia, Ruiying Zhang, Wen Wang and Xia Xiang

Food Research International, 2023, 174, 113517
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Investigation on the inhibition mechanism and binding behavior of cryptolepine to α-glucosidase and its hypoglycemic activity by multi-spectroscopic method

Xiaofeng Min, Suqin Guo, Yujing Lu and Xuetao Xu

Journal of Luminescence, 2024, 269, 120437
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Synthesis, Biological Evaluation, and Computational Studies of Phenolic N-Acetylglucosamine Glycosides as α-Glucosidase Inhibitors

Wenjie Wang, Kun Gao, Guantian Li, Zongji Wang, Kecheng Li, Song Liu, Huahua Yu and Ronge Xing

Marine Drugs, 2026, 24, 84
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Insight into the Inhibitory Mechanisms of Hesperidin on α-Glucosidase through Kinetics, Fluorescence Quenching, and Molecular Docking Studies

Kumaravel Kaliaperumal, Linyan Zhang, Liangliang Gao, Qin Xiong, Yan Liang, Yueming Jiang and Jun Zhang

Foods, 2023, 12, 4142
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Sensitive detection of trilobatin in tea beverages based on hydroxy-functionalized Ag@COF SERS substrate

Weinan Guan, Guoqing Chen, Zichen Yang, Taiqun Yang, Chaoqun Ma, Lei Li, Hui Gao, Chun Zhu, Zichen Cai, Yan Zhou, Wei Zhang and Xin Li

Vibrational Spectroscopy, 2024, 130, 103623
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Pectolinarigenin shows lipid‐lowering effects by inhibiting fatty acid biosynthesis in vitro and in vivo

Zhou Lan, Kun Zhang, Jianhui He, Qiong Kang, Wei Meng and Songhua Wang

Phytotherapy Research, 2023, 37, 913
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Antihyperglycemic effects of Lysiphyllum strychnifolium leaf extract in vitro and in vivo

Arman Syah Goli, Vilasinee Hirunpanich Sato, Hitoshi Sato, Savita Chewchinda, Jiraporn Leanpolchareanchai, Jannarin Nontakham, Jantana Yahuafai, Thavaree Thilavech, Pongsatorn Meesawatsom and Metawee Maitree

Pharmaceutical Biology, 2023, 61, 189
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Influence of catechin–PAYCS interactions on gastrointestinal structural and bioactivity stability: Key mechanisms in digestive enzymes inhibition

Jieqiong Chen, Chunyan Lin, Lijia Yang, Yang Liu, Guowan Su, Yehui Zhang, Weifeng Liu, Mouming Zhao, Xuan Zhao, Lihua Huang and Tiantian Zhao

Food Chemistry, 2025, 490, 145132
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Regulation of β-Disaccharide Accumulation by β-Glucosidase Inhibitors to Enhance Cellulase Production in Trichoderma reesei

Tingting Long, Peng Zhang, Jingze Yu, Yushan Gao, Xiaoqin Ran and Yonghao Li

Fermentation, 2022, 8, 232
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Astragalin Exerted Hypoglycemic Effect by Both Inhibiting α-Glucosidase and Modulating AMPK Signaling Pathway

Qian Li, Zhangchang Yang, Huijie Lu, Fan Liu, Donglai Zhou and Yuxiao Zou

Nutrients, 2025, 17, 406
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Application of Molecular Simulation Methods in Food Science: Status and Prospects

Yuandong Yu, Shiqi Xu, Ran He and Guizhao Liang

J. Agric. Food Chem., 2023, 71, 2684
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Comparative study on metabolite variations of two rose teas by plant metabolomics and revealing their skin‐whitening candidates by spectrum–effect relationship analysis

Jian Xu, Hongwei Ye, Xindan Zhang, Yangbin Lv, Shengqiang Tong, Biao Liu, Zhimin Ou and Chu Chu

Phytochemical Analysis, 2025, 36, 80
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The improved inhibition of Mn (II)-EGCG on α-glucosidase: Characteristics and interactions properties

Zhenru Li, Mengchen Kang, Shuangling Zhang, Suzhi Zhang, Zixuan Dongye, Li Wang, Chengwang Chen, Xiaofang Cheng, Yaru Qian and Yuhang Ren

Journal of Molecular Structure, 2023, 1283, 135314
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Inhibition effects of xanthohumol on α-amylase and α-glucosidase: Kinetics, multi-spectral and molecular docking

Bin Zhang, Yuansheng Deng, Yuanrui Song, Fa Yang, Yingying He and Tao Guo

International Journal of Biological Macromolecules, 2025, 311, 143676
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Inhibition of α‐glucosidase activity by curcumin loaded on ZnO@rGO nanocarrier for potential treatment of diabetes mellitus

Linghong Liu, Zhu Wang, Pei Lay Yap, Qiulan Zhang, Yongnian Ni and Dusan Losic

Luminescence, 2024, 39
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