A tutorial review for research laboratories to support the vital path toward inherently sustainable and green synthetic chemistry

Sarah M. Kernaghan, Tracey Coady, Michael Kinsella and Claire M. Lennon

RSC Sustainability, 2024, 2, 578
DOI: 10.1039/D3SU00324H

Molecular simulations explain the exceptional thermal stability, solvent tolerance and solubility of protein–polymer surfactant bioconjugates in ionic liquids

Sudarshan Behera and Sundaram Balasubramanian

Phys. Chem. Chem. Phys., 2022, 24, 21904
DOI: 10.1039/D2CP02636H

Is enzyme immobilization a mature discipline? Some critical considerations to capitalize on the benefits of immobilization

Juan M. Bolivar, John M. Woodley and Roberto Fernandez-Lafuente

Chem. Soc. Rev., 2022, 51, 6251
DOI: 10.1039/D2CS00083K

Classifying deep eutectic solvents for polymer solvation via intramolecular dimer formation

Shreya Juneja and Siddharth Pandey

Phys. Chem. Chem. Phys., 2022, 24, 21655
DOI: 10.1039/D2CP03114K

The attenuating ability of deep eutectic solvents towards the carboxylated multiwalled carbon nanotubes induced denatured β-lactoglobulin structure

Niketa Yadav, Sanjay Mor and Pannuru Venkatesu

Phys. Chem. Chem. Phys., 2023, 25, 20519
DOI: 10.1039/D3CP02908E

Essential dynamics of ubiquitin in water and in a natural deep eutectic solvent

Inês Gomes, Gabriel. F. Martins and Nuno Galamba

Phys. Chem. Chem. Phys., 2024, 26, 18244
DOI: 10.1039/D4CP01773K

Deep eutectic solvents as a stabilising medium for NAD coenzyme: unravelling the mechanism behind coenzyme stabilisation effect

Mia Radović, Lucija Hok, Manuela Panić, Marina Cvjetko Bubalo, Robert Vianello, Marijana Vinković and Ivana Radojčić Redovniković

Green Chem., 2022, 24, 7661
DOI: 10.1039/D2GC02656B

Green-friendly and biocompatible deep eutectic solvents for pharmaceuticals, biocatalysis, and biosensing applications

Yu Wang, Xueliang Zheng, Jing Li, Zhihao Chen, Tongtong Wang, Wenjie Miao, Shuocong Wang, Si Li and Tingting Jiang

Green Chem., 2026, 28, 1316
DOI: 10.1039/D5GC06075C

Structural insights into novel therapeutic deep eutectic systems with capric acid using 1D, 2D NMR and DSC techniques with superior gut permeability

Bayan Alkhawaja, Faisal Al-Akayleh, Jehad Nasereddin, Muhammad Kamran, Tim Woodman, Zaid Al-Rubaye, Nidal Qinna, Mayyas Al-Remawi and Ali R. Olaimat

RSC Adv., 2024, 14, 14793
DOI: 10.1039/D4RA01469C

Amphipathic engineering of magnetic composites reinforced with ion-copolymer-activated protein-bioconjugate functionalized surface

Zhiyong Guo, Guobin Huang, Chen Zhang, Qiuhong Yao, Tingxiu Ye, Li Zhang and Xi Chen

Mater. Chem. Front., 2022, 6, 237
DOI: 10.1039/D1QM01354H

Natural deep eutectic solvents (NaDES): translating cell biology to processing

Miša Mojca Cajnko, Filipa A. Vicente, Uroš Novak and Blaž Likozar

Green Chem., 2023, 25, 9045
DOI: 10.1039/D3GC01913F

Current understanding and insights towards protein stabilization and activation in deep eutectic solvents as sustainable solvent media

Niketa Yadav and Pannuru Venkatesu

Phys. Chem. Chem. Phys., 2022, 24, 13474
DOI: 10.1039/D2CP00084A

Deep eutectic solvents towards green polymeric materials

Udyani Aloka Weerasinghe, Tingting Wu, Pei Lin Chee, Pek Yin Michelle Yew, Hiang Kwee Lee, Xian Jun Loh and Kai Dan

Green Chem., 2024, 26, 8497
DOI: 10.1039/D4GC00532E

Unravelling the influence of choline chloride-based deep eutectic solvents on lysozyme: a comparative study of fructose and formic acid donors

Ntebogeng Mqoni, Sheldon Sookai, Ajit Kumar, Lebogang Katata-Seru, Faruq Mohammad, Pannuru Venkatesu, Indra Bahadur and Ahmed Abdullah Soleiman

RSC Adv., 2025, 15, 25483
DOI: 10.1039/D5RA02315G

Extraction, purification, and functionality of proteins using deep eutectic solvents: a review

Ali Khanalipour, Mahnaz Tabibiazar, Behzad Masoumi, Solmaz Tabibi Azar, Aylin Allahyari and Maryam Borji

Journal of Molecular Liquids, 2025, 429, 127623
DOI: 10.1016/j.molliq.2025.127623

Study on drug separation in Two-Phase aqueous systems using deep eutectic solvent consisting of choline chloride and 1,2 propanediol

Sara Mashhaditafreshi and Ali Haghtalab

Journal of Molecular Liquids, 2024, 393, 123603
DOI: 10.1016/j.molliq.2023.123603

Advances in metal recovery from e-waste: Green solvent assessments with ionic liquids and deep eutectic solvents

Hussein K. Amusa, Safique Anwer, Abdulhammed K. Hamzat, Idowu A. Adeyemi, Adewale Giwa, Jisha K. Ali, Inas M. AlNashef and Emad Alhseinat

Sustainable Chemistry for the Environment, 2026, 13, 100307
DOI: 10.1016/j.scenv.2025.100307

Site-specific water dynamics drives protein stability in hydrated deep eutectic solvents

Tanmoy Khan, Kuntal Debnath, Kuldeep Singh Negi and Pratik Sen

Biophysical Journal, 2025, 124, 4255
DOI: 10.1016/j.bpj.2025.10.019

Water-modulated structure and dynamics in aqueous choline chloride-polyol deep eutectic solvents: Insights from molecular dynamic simulations

Roja Satvika Puvvada, Ivy Das Sarkar and Suman Das

The Journal of Chemical Physics, 2025, 163
DOI: 10.1063/5.0299282

Corner Engineering: Tailoring Enzymes for Enhanced Resistance and Thermostability in Deep Eutectic Solvents

Xinyue Wang, Yijie Sheng, Haiyang Cui, Jie Qiao, Yibo Song, Xiujuan Li and He Huang

Angew Chem Int Ed, 2024, 63
DOI: 10.1002/anie.202315125

Effects of deep eutectic solvents on the activity and stability of enzymes

Sarvenaz Moradi Taklimi, Adeleh Divsalar, Behafarid Ghalandari, Xianting Ding, Maria Luisa Di Gioia, Karzan A. Omar and Ali Akbar Saboury

Journal of Molecular Liquids, 2023, 377, 121562
DOI: 10.1016/j.molliq.2023.121562

Mechanistic Insights into the Stabilizing Role of Deep Eutectic Solvents for Nucleic Acids: An In Silico Analysis

David E. Hardy, Adam Albert, Jenna Lipani, Zachary J. Metott, Arsalan Mirjafari and Durgesh V. Wagle

J. Phys. Chem. B, 2025, 129, 5674
DOI: 10.1021/acs.jpcb.5c00799

Design of protein-stabilizing deep eutectic solvents: a combined experimental and computational approach

Anja Damjanović, Marijan Logarušić, Ana Jurinjak Tušek, Mia Radović, Nika Ukalović, Tin Weitner, Thanos Andreou, Marina Cvjetko Bubalo and Ivana Radojčić Redovniković

Journal of Molecular Liquids, 2025, 436, 128259
DOI: 10.1016/j.molliq.2025.128259

Quantifying green innovation: A bibliometric analysis of deep eutectic solvents and applications as eco-friendly solvents

Muhammad Nawaz, Muhammad Irfan, Khadija Zahra, Humbul Suleman, Mohamad Azmi Bustam and Abdulhalim Shah Maulud

Journal of Ionic Liquids, 2025, 5, 100165
DOI: 10.1016/j.jil.2025.100165

Deep Eutectic Solvents for Batteries and Fuel Cells: Biosubstitution, Advantages, Challenges, and Future Directions

Yonchen Hariyanto, Ying Ki Ng, Zhi Zhou Siew, Chu Yong Soon, Adrian C. Fisher, Leopold Kloyer, Chen Wai Wong and Eric Wei Chiang Chan

Energy Fuels, 2023, 37, 18395
DOI: 10.1021/acs.energyfuels.3c02870

Extraction of glucosinolates from Raphani semen using natural green deep eutectic solvents combined with ultrasound-assisted techniques: process optimization, component analysis, and antibacterial activity evaluation

Mengqi Yan, Sen Li, Ruitong Du, Kang Yang, Zejun Liu, Bingyou Yang, Haixue Kuang and Zhibin Wang

LWT, 2025, 224, 117814
DOI: 10.1016/j.lwt.2025.117814

Ionic Liquids: Momentous Tools in Transdermal Delivery of Biomacromolecules

Lisha Li, Zongguang Tai, Xiying Wu, Junchao Wu, Tingrui Zhang, Zhongjian Chen and Quangang Zhu

Advanced Therapeutics, 2023, 6
DOI: 10.1002/adtp.202200332

Moving Beyond Choline: Protic Choline Iodide Analogues toward Cosolvent-Free, Self-Contained Deep Eutectic Electrolytes for Dye-Sensitized Solar Cells

Dustin J. Boogaart and Gary A. Baker

ACS Appl. Eng. Mater., 2024, 2, 360
DOI: 10.1021/acsaenm.3c00673

Application of natural deep eutectic solvents in design and formulation of food grade-Pickering emulsions: a review

Maryam Borji, Aylin Allahyari, Parisa Ahmadi, Ali Jahanban-Esfahlan, Ali Khanalipour and Mahnaz Tabibiazar

Journal of Molecular Liquids, 2026, 444, 129184
DOI: 10.1016/j.molliq.2025.129184

Water Miscibility, Surface Tension, Density, and Dynamic Viscosity of Hydrophobic Deep Eutectic Solvents Composed of Capric Acid, Menthol, and Thymol

Deepika, Shreya Juneja and Siddharth Pandey

J. Chem. Eng. Data, 2022, 67, 3400
DOI: 10.1021/acs.jced.2c00495

Assessing the Effect of Deep Eutectic Solvents on α‐Chymotrypsin Thermal Stability and Activity

Nicolás F. Gajardo‐Parra, Esteban Cea‐Klapp, Anshu Chandra, Roberto I. Canales, José Matías Garrido, Christoph Held and Nadia Guajardo

ChemSusChem, 2025, 18
DOI: 10.1002/cssc.202401414

Protein stability in a natural deep eutectic solvent: Preferential hydration or solvent slaving?

Inês Gomes and Nuno Galamba

The Journal of Chemical Physics, 2023, 159
DOI: 10.1063/5.0177095

The Synthesis of Binary DES and Its Application in the Pretreatment of Wool Keratin Extraction by the L-cysteine Redox Method

Yan Liu, Xin Wang, Yang Song and Rong Li

Journal of Natural Fibers, 2022, 19, 10872
DOI: 10.1080/15440478.2021.2002776

Designing Low Toxic Deep Eutectic Solvents for the Green Recycle of Lithium‐Ion Batteries Cathodes

Yilin Li, Mingjie Sun, Yanbo Cao, Keying Yu, Zixuan Fan and Yuanyuan Cao

ChemSusChem, 2024, 17
DOI: 10.1002/cssc.202301953

Exploring the potential of deep eutectic solvents (DES) in bioactive natural product research: from DES to NaDES, THEDES, and beyond

Mariana Ruesgas Ramon, Erwann Durand, Karlina Garcia-Sosa and Luis Manuel Peña-Rodríguez

PeerJ Analytical Chemistry, 2023, 5, e28
DOI: 10.7717/peerj-achem.28

Improved activity and thermostability of glycosylating biocatalysts acting in neat natural deep eutectic solvents: Pushing boundaries of enzymes

K. Bautista-Rangel, L.F. Losoya-Uribe, M. Rodríguez-Gonzalez, G. Saab-Rincón, A. López-Munguía and E. Castillo

International Journal of Biological Macromolecules, 2025, 318, 145012
DOI: 10.1016/j.ijbiomac.2025.145012

Applications of therapeutic deep eutectic solvents (THEDESs) as antimicrobial and anticancer agents

Hala Bakr El-Nassan

Pharmaceutical Development and Technology, 2024, 29, 1084
DOI: 10.1080/10837450.2024.2421786

Comparison and Validation of Force Fields for Deep Eutectic Solvents in Combination with Water and Alcohol Dehydrogenase

Jan Philipp Bittner, Lei Huang, Ningning Zhang, Selin Kara and Sven Jakobtorweihen

J. Chem. Theory Comput., 2021, 17, 5322
DOI: 10.1021/acs.jctc.1c00274

Therapeutic deep eutectic solvents assisted the encapsulation of curcumin in alginate-chitosan hydrogel beads

Joana M. Silva, Eduardo Silva and Rui L. Reis

Sustainable Chemistry and Pharmacy, 2021, 24, 100553
DOI: 10.1016/j.scp.2021.100553

Deep eutectic solvents for protein extraction: mechanisms, performance, and green metrics

Joel Ching Jue Wong, Ianatul Khoiroh, Suyin Gan and Anna K. Croft

Journal of Molecular Liquids, 2025, 438, 128636
DOI: 10.1016/j.molliq.2025.128636

Green preparation of graphene oxide-incorporated monoliths for pH-controlled protein enrichment and clinical biomarker detection

Xue Zhang, Fenghua Xu, Rui Wu, Huiying Zhang, Yufei Shi, Zhaosheng Liu and Xin Dong

Analytica Chimica Acta, 2026, 1397, 345266
DOI: 10.1016/j.aca.2026.345266

Exploring the potential of combining menthol-thymol deep eutectic solvent and solid microneedles for cutaneous peptide delivery

Shabir Ahmad, Grzegorz S. Czyrski, Christian Janfelt, Stéphanie Baud, Massimo Fresta and Andrea Heinz

European Journal of Pharmaceutical Sciences, 2025, 215, 107336
DOI: 10.1016/j.ejps.2025.107336

Effective lipase extraction: Designing a natural liquid support for immobilization

Andrea Fernández, María A. Longo, Francisco J. Deive, María S. Álvarez and Ana Rodríguez

Separation and Purification Technology, 2021, 278, 119601
DOI: 10.1016/j.seppur.2021.119601

Highly Efficient Intramolecular Excimer Formation in a Disulfide-Linked Dipyrenyl Compound: Proton Recognition and Fluidity Assessment

Shreya Juneja, Siddharth Mishra, Govind Maurya, V. Haridas and Siddharth Pandey

J. Phys. Chem. A, 2023, 127, 10197
DOI: 10.1021/acs.jpca.3c06576

The Physicochemical Properties and Plausible Implication of Deep Eutectic Solvents in Analytical Techniques

Vahishta K. Katrak, Nensi A. Patel and Sushma P. Ijardar

Critical Reviews in Analytical Chemistry, 2025, 1
DOI: 10.1080/10408347.2025.2486209

Unveiling the high-pressure behavior of thymol+carvone NADES: A combined experimental-computational approach

Ylenia F. Rodríguez, Cristina Benito, Santiago Aparicio and Jose L. Trenzado

The Journal of Supercritical Fluids, 2025, 215, 106408
DOI: 10.1016/j.supflu.2024.106408

Transforming nature into the next generation of bio-based flexible devices: New avenues using deep eutectic systems

Josué D. Mota-Morales and Eden Morales-Narváez

Matter, 2021, 4, 2141
DOI: 10.1016/j.matt.2021.05.009

Deep-eutectic solvent-assisted green synthesis of MAX-phase Cr2AlC and its 2D-MXene derivative Cr2CTx towards room-temperature detection of ammonia gas

Hembram Lokeshwar, Lakkimsetti Lakshmi Praveen, Saumen Mandal and Nanda Shakti

Ceramics International, 2025, 51, 53681
DOI: 10.1016/j.ceramint.2025.09.113

Thermodynamic properties, electrochemical properties, and interaction behaviors of quaternary ammonium salts-based deep eutectic solvents

Jian Wang, Chengmiao Ma, Zhixu Zhang, Xinyi Ge, Qingguo Zhang and Ying Wei

Journal of Molecular Liquids, 2024, 408, 125384
DOI: 10.1016/j.molliq.2024.125384

Optimisation and modelling of ultrasonic-assisted extraction of canthaxanthin from Chromochloris zofingiensis using eutectic solvents

Dan Yang, Weijia Qiu, Ying Xu, Zhangli Hu and Liyan Wang

Industrial Crops and Products, 2023, 202, 117002
DOI: 10.1016/j.indcrop.2023.117002

β-Diketone-Driven Deep Eutectic Solvent for Ultra-Efficient Natural Stable Lithium-7 Isotope Separation

Zexing Xie, Meiying Xie, Tingting Tang, Fan Yang, Liyan Xue and Zhengming Jiang

Separations, 2023, 10, 111
DOI: 10.3390/separations10020111

Iodine‐Functionalized Magnetic Reduced Graphene Oxide as an Efficient Nanocatalyst for Acetylation of Phenol, Alcohol, and Sugar Derivatives

Saeedeh Toorchi Roudsari and Sodeh Sadjadi

ChemistrySelect, 2023, 8
DOI: 10.1002/slct.202204067

Rapeseed as the source of proteins: A review

Damjana Tomić, Jovana Simeunović, Branislava Đermanović, Aleksandar Marić, Marijana Sakač, Bojana Šarić and Pavle Jovanov

Food & Feed Res, 2025, 52, 267
DOI: 10.5937/ffr0-56718

Medium engineering of phenylethanoid transfructosylation catalysed by yeast β-fructofuranosidase

Klaudia Karkeszová, Monika Antošová, Elena Karnišová Potocká, Vladimír Mastihuba and Milan Polakovič

Bioprocess Biosyst Eng, 2023, 46, 237
DOI: 10.1007/s00449-022-02828-3

Deep Eutectic Solvents for Biotechnology Applications

Olga V. Morozova, Irina S. Vasil’eva, Galina P. Shumakovich, Elena A. Zaitseva and Alexander I. Yaropolov

Biochemistry Moscow, 2023, 88, S150
DOI: 10.1134/S0006297923140092

Ionic liquids and eutectic mixtures for virus inactivation – A review of molecular mechanisms and environmental remediation potential

Mujeeb Kareem, Dean Everett, Enas Al Nashef and Ludovic F. Dumée

Journal of Water Process Engineering, 2025, 79, 108950
DOI: 10.1016/j.jwpe.2025.108950

Green solvents tailored nanostructures of block copolymers and their potential applications in drug delivery

Ambrish Kumar, Moumita Saha, Ritik Vishwakarma, Kamalakanta Behera and Shruti Trivedi

Journal of Molecular Liquids, 2024, 410, 125642
DOI: 10.1016/j.molliq.2024.125642

Combustion behaviour of blends of lignite coal with cashew nut waste using choline chloride and 2 glycerol deep eutectic solvent

A. Kiruthika, R. Anantharaj, D. Praveen Sam and M. Gayathri

Indian Chemical Engineer, 2026, 1
DOI: 10.1080/00194506.2026.2649468

Hydration-mediated stabilization and anti-aggregation of soy and whey protein isolates, insulin, and collagen in hydrophilic deep eutectic solvents

Jiawen Chen, Keting Chen, Tianqi Liu, Mi Wang, Xiangli Liu, Jichuan Zhang and Jiaheng Zhang

Journal of Colloid and Interface Science, 2026, 707, 139683
DOI: 10.1016/j.jcis.2025.139683

Strategies to Prepare Chitin and Chitosan-Based Bioactive Structures Aided by Deep Eutectic Solvents: A Review

D. Alonzo Durante-Salmerón, Isabel Fraile-Gutiérrez, Rubén Gil-Gonzalo, Niuris Acosta, Inmaculada Aranaz and Andrés R. Alcántara

Catalysts, 2024, 14, 371
DOI: 10.3390/catal14060371

Lysozyme stability in various deep eutectic solvents using molecular dynamics simulations

Akshatha Hebbar, Poulumi Dey and Anoop Kishore Vatti

Journal of Biomolecular Structure and Dynamics, 2024, 42, 13325
DOI: 10.1080/07391102.2023.2275178

Natural Protein and Lipid Carriers as Food Grade Nanocages for Delivering Bioactive Compounds with Improved Therapeutic Efficacy: A Review

Priya Patel, Kevin Kumar Garala, Sudarshan Singh, Bhupendra G. Prajapati and Mihir Raval

CMC, 2025, 32, 6723
DOI: 10.2174/0109298673309672241113102535

Do Dipolar Cosolvents Mitigate Microheterogeneity in Deep Eutectic Solvents? Solvation Dynamics and Solute Rotations in Glyceline/Methanol Solutions

Christian Green, Christopher A. Rumble and Mark P. Heitz

J. Phys. Chem. B, 2026, 130, 396
DOI: 10.1021/acs.jpcb.5c06534

Research progress in Ramie fiber extraction: Degumming method, working mechanism, and fiber performance

Qi Tang, Yixiao Chen, Mingjuan Du, Jianyong Yu, Zhaoling Li and Bin Ding

Industrial Crops and Products, 2024, 222, 119876
DOI: 10.1016/j.indcrop.2024.119876

Structural characteristics and biological activity of lactic acid bacteria exopolysaccharides separated by ethanol/(NH4)2SO4 ATPS

Bin Jiang, Peifeng Chen, Jiaxuan Guo, Bing Han, Hongwei Jin, Dongmei Li, Chunhong Liu and Zhibiao Feng

International Journal of Biological Macromolecules, 2023, 244, 125451
DOI: 10.1016/j.ijbiomac.2023.125451

Application of deep eutectic solvents in protein extraction and purification

Hou Bowen, Rabia Durrani, André Delavault, Erwann Durand, Jiang Chenyu, Long Yiyang, Song Lili, Song Jian, Huan Weiwei and Gao Fei

Front. Chem., 2022, 10
DOI: 10.3389/fchem.2022.912411

The multiple enhancements of deep eutectic solvent on cellulase significantly improve the saccharification efficiency of lignocellulosic biomass

Yanming Wang, Ailin Wang, Shiwei Liu, Lu Li, Yue Liu, Yuxiang Liu, Genkuo Nie, Shuangxi Nie, Shuangquan Yao and Hailong Yu

Chemical Engineering Journal, 2024, 489, 151439
DOI: 10.1016/j.cej.2024.151439

Understanding the intricacy of protein in hydrated deep eutectic solvent: Solvation dynamics, conformational fluctuation dynamics, and stability

Tanmoy Khan, Nilimesh Das, Kuldeep Singh Negi, Suman Bhowmik and Pratik Sen

International Journal of Biological Macromolecules, 2023, 253, 127100
DOI: 10.1016/j.ijbiomac.2023.127100

Evaluation of canonical choline chloride based deep eutectic solvents as dye-sensitized solar cell electrolytes

Dustin J. Boogaart, Jeremy B. Essner and Gary A. Baker

The Journal of Chemical Physics, 2021, 155
DOI: 10.1063/5.0055644

Molecular dynamics insights into the dynamical behavior of structurally modified water in aqueous deep eutectic solvents (ADES)

Arnab Sil, Sangeeta, Vishnu Poonia, Suman Das and Biswajit Guchhait

The Journal of Chemical Physics, 2024, 161
DOI: 10.1063/5.0223828

How to improve the efficiency of biocatalysis in non-aqueous pure deep eutectic solvents: A case study on the lipase-catalyzed transesterification reaction

Jun Cao, Rong Wu, Feng Zhu, Qihui Dong and Erzheng Su

Biochemical Engineering Journal, 2022, 179, 108336
DOI: 10.1016/j.bej.2022.108336

Green in the deep blue: deep eutectic solvents as versatile systems for the processing of marine biomass

Colin McReynolds, Amandine Adrien, Natalia Castejon and Susana C. M. Fernandes

Green Chemistry Letters and Reviews, 2022, 15, 383
DOI: 10.1080/17518253.2022.2065890

Natural Deep Eutectic Solvents as Absorbing Solution and Preparation Solvent of Perovskite Nanocrystals Simultaneously for CH3I Gas Visual Sensing

Jiamin Luo, Heng Lu, Bao-Ying Wen, Qiaowen Zheng, Junying Zhang, Yishan Li, Wenping Hong, Shanshan Zhao, Libo Shun, Feiming Li, Zhixiong Cai, Jin-Ming Lin, Qiang Chen, Maosheng Zhang and Jian-Feng Li

Anal. Chem., 2024, 96, 15816
DOI: 10.1021/acs.analchem.4c04776

Halide effects on the performance of equimolar choline halide: guanidinium thiocyanate deep eutectic solvents as dye-sensitized solar cell electrolytes

Dustin J. Boogaart, Jeremy B. Essner and Gary A. Baker

Green Chemistry Letters and Reviews, 2022, 15, 615
DOI: 10.1080/17518253.2022.2111231

Effect of Hydrated Deep Eutectic Solvents on the Thermal Stability of DNA

Mariagrazia Tortora, Jacopo Vigna, Ines Mancini, Andrea Mele, Alessandro Gessini, Claudio Masciovecchio and Barbara Rossi

Crystals, 2021, 11, 1057
DOI: 10.3390/cryst11091057

Valorization of biomass for food protein via deep eutectic solvent extraction: Understanding the extraction mechanism and impact on protein structure and properties

Mohamad Ariff Hanafi, Farooq Anwar and Nazamid Saari

Food Frontiers, 2024, 5, 1265
DOI: 10.1002/fft2.389

Purification of phycocyanin from Spirulina platensis using deep eutectic solvent-based aqueous two-phase system: Correlation between hydrogen bond acceptor and protein structure

Ningqiao Kong, Wenyu Zheng, Mouming Zhao and Feibai Zhou

Separation and Purification Technology, 2025, 377, 134220
DOI: 10.1016/j.seppur.2025.134220

Synergistic Therapeutic Potential of New Metal-Free Deep Eutectic Solvents: Synthesis, Physicochemical, Biological, and Ab Initio Studies

Muhammad Sarfraz, Danish Ali, Asma Yaqoob, Ge Yang, Muhammad Adnan, Kashaf Imran, Bing Yu and Hailin Cong

J. Phys. Chem. B, 2026, 130, 1634
DOI: 10.1021/acs.jpcb.5c07134

Decanoic Acid Based Deep Eutectic Solvents: Constituent-Controlled Physicochemical Properties and Solvatochromic Probe Behavior

Anushis Patra, Vaishali Khokhar and Siddharth Pandey

Ind. Eng. Chem. Res., 2022, 61, 14702
DOI: 10.1021/acs.iecr.2c02608

Developing new benzilic acid-based hydrophobic deep eutectic solvents: study towards dye extraction and antimicrobial efficiency

Jenish Parekh, Abhishek Munjapara, Devashish Pandya, Avani Bhimani, Ashokkumar Bishoyi, Subrata Patra and Hetal Jebaliya

International Journal of Environmental Analytical Chemistry, 2025, 105, 7656
DOI: 10.1080/03067319.2025.2452950

Discrepant Effects of Hydrated and Neat Reline on the Conformational Stability of a Knotted Protein

Sanjib Thakuria and Sandip Paul

J. Phys. Chem. B, 2025, 129, 4629
DOI: 10.1021/acs.jpcb.5c00148

DNA nanotechnology in ionic liquids and deep eutectic solvents

Beñat Olave

Critical Reviews in Biotechnology, 2024, 44, 941
DOI: 10.1080/07388551.2023.2229950

Temperature-dependent ultrafast solvation dynamics of choline chloride-based deep eutectic solvent (DES) and hydroxyl functionalized room temperature ionic liquids (RTILs): Exploring the difference in solvent response between DES and RTILs

Sahadev Barik, Naupada Preeyanka, Manjari Chakraborty, Amita Mahapatra and Moloy Sarkar

Journal of Molecular Liquids, 2022, 367, 120545
DOI: 10.1016/j.molliq.2022.120545

Merging Iron Catalysis and Enzymatic Reduction: A Deracemization Strategy of Secondary Alcohols in Iron‐Based Deep Eutectic Solvents

Mara Pulpito, Luciana Cicco, Filippo Maria Perna, Paola Vitale, Vito Capriati and Vicente Gotor‐Fernández

ChemCatChem, 2025, 17
DOI: 10.1002/cctc.202501019

Stabilization of Non-Native Folds and Programmable Protein Gelation in Compositionally Designed Deep Eutectic Solvents

Adrian Sanchez-Fernandez, Jia-Fei Poon, Anna Elizabeth Leung, Sylvain François Prévost and Cedric Dicko

ACS Nano, 2024, 18, 18314
DOI: 10.1021/acsnano.4c01950

Redefining the landscape of protein extraction and separation from various sources using deep eutectic solvents

Vahishta K. Katrak and Sushma P. Ijardar

Trends in Food Science & Technology, 2024, 153, 104733
DOI: 10.1016/j.tifs.2024.104733

Hydration in Deep Eutectic Solvents Induces Non-monotonic Changes in the Conformation and Stability of Proteins

Adrian Sanchez-Fernandez, Medina Basic, Jenny Xiang, Sylvain Prevost, Andrew J. Jackson and Cedric Dicko

J. Am. Chem. Soc., 2022, 144, 23657
DOI: 10.1021/jacs.2c11190

Amino Acid- and Dipeptide Amphiphile-Based Supramolecular Eutectogels: Soft Materials for Drug Entrapment–Release and Wastewater Treatment

Aftab Hossain Khan, Sudeshna Pal, Anup Kumar Ghosh and Prasanta Kumar Das

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