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DOI: 10.1039/P19940001997 (Paper) Reference Section for: J. Chem. Soc., Perkin Trans. 1, 1994, 1997-2006

Design and synthesis of transition-state analogues for a cationic cyclisation

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Ian M. Bell, Chris Abell and Finian J. Leeper

Abstract

Transition-state analogues based upon the 6-(hydroxymethyl)-13-azagona-1,3,5(10),8-tetraene structure (e.g., 40) have been designed and synthesized as part of a programme to elicit antibodies capable of catalysing cationic cyclisations. Methodology for conjugating such analogues to proteins has also been developed.

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