Issue 60, 2014

Tuning the thermosensitive properties of hybrid collagen peptide–polymer hydrogels

Abstract

A hybrid hydrogel based on collagen-mimetic peptides has been designed with tunable thermosensitive properties. By changing the number of POG repeats within the collagen peptide sequence, the thermal stability of the triple helical physical crosslinks of a peptide–polymer conjugate can be altered, thus tuning the stiffness of the hydrogel as a function of temperature. This report focuses on three different thermally responsive collagen peptide, PEG-based hydrogels and validates their use as stimuli-responsive materials.

Graphical abstract: Tuning the thermosensitive properties of hybrid collagen peptide–polymer hydrogels

Supplementary files

Article information

Article type
Communication
Submitted
29 avr. 2014
Accepted
05 juin 2014
First published
05 juin 2014

Chem. Commun., 2014,50, 8174-8176

Author version available

Tuning the thermosensitive properties of hybrid collagen peptide–polymer hydrogels

C. M. Rubert Pérez, L. A. Rank and J. Chmielewski, Chem. Commun., 2014, 50, 8174 DOI: 10.1039/C4CC03171G

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