Issue 37, 2019

New avenues for C–B bond formation via radical intermediates

Abstract

This perspective gives an overview on recent findings in the emerging area of C-radical borylation using diborons as radical trapping reagents. Aryl, vinyl and alkyl boronic esters can be accessed via such an approach under mild conditions. These processes are complementary to established transition metal catalysed cross coupling reactions. Radical borylations can be conducted in the absence of a transition metal but some processes require transition metals as catalysts. It will be shown that various readily available C-radical precursors can be used to run these borylations. For a better understanding of the chemistry, mechanistic discussions are also presented and an outlook on this topic will be provided at the end of the article.

Graphical abstract: New avenues for C–B bond formation via radical intermediates

Article information

Article type
Perspective
Submitted
26 juil. 2019
Accepted
03 sept. 2019
First published
03 sept. 2019
This article is Open Access

All publication charges for this article have been paid for by the Royal Society of Chemistry
Creative Commons BY-NC license

Chem. Sci., 2019,10, 8503-8518

New avenues for C–B bond formation via radical intermediates

F. W. Friese and A. Studer, Chem. Sci., 2019, 10, 8503 DOI: 10.1039/C9SC03765A

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