Issue 48, 2018

Enantioselective total synthesis of sagittacin E and related natural products

Abstract

The first enantioselective total synthesis of eremophilane-type sesquiterpenoids, sagittacin E and related natural products, was achieved. This synthesis features an asymmetric desymmetrization by Shi asymmetric epoxidation, intramolecular aldol-type cyclization, allylic oxidation of a 1,4-diene compound, and stereoselective epoxidation.

Graphical abstract: Enantioselective total synthesis of sagittacin E and related natural products

Supplementary files

Article information

Article type
Communication
Submitted
27 avr. 2018
Accepted
23 mai 2018
First published
29 mai 2018

Chem. Commun., 2018,54, 6165-6168

Enantioselective total synthesis of sagittacin E and related natural products

H. Abe, M. Fujimaki, E. Nakagawa, T. Kobayashi and H. Ito, Chem. Commun., 2018, 54, 6165 DOI: 10.1039/C8CC03438A

To request permission to reproduce material from this article, please go to the Copyright Clearance Center request page.

If you are an author contributing to an RSC publication, you do not need to request permission provided correct acknowledgement is given.

If you are the author of this article, you do not need to request permission to reproduce figures and diagrams provided correct acknowledgement is given. If you want to reproduce the whole article in a third-party publication (excluding your thesis/dissertation for which permission is not required) please go to the Copyright Clearance Center request page.

Read more about how to correctly acknowledge RSC content.

Social activity

Spotlight

Advertisements