Issue 58, 2016

A highly selective fluorogenic probe for the detection and in vivo imaging of Cu/Zn superoxide dismutase

Abstract

Copper/zinc superoxide dismutase (Cu/Zn SOD) is an essential enzyme that protects tissue from oxidative damage. Herein we report the first fluorogenic probe (SODO) for the detection and in vivo imaging of Cu/Zn SOD. SODO represents a unique chemical probe for translational imaging studies of Cu/Zn SOD in inflammatory disorders.

Graphical abstract: A highly selective fluorogenic probe for the detection and in vivo imaging of Cu/Zn superoxide dismutase

Supplementary files

Article information

Article type
Communication
Submitted
05 janv. 2016
Accepted
25 févr. 2016
First published
25 févr. 2016
This article is Open Access
Creative Commons BY license

Chem. Commun., 2016,52, 9093-9096

Author version available

A highly selective fluorogenic probe for the detection and in vivo imaging of Cu/Zn superoxide dismutase

L. Zhang, J. C. Er, H. Jiang, X. Li, Z. Luo, T. Ramezani, Y. Feng, M. K. Tang, Y. Chang and M. Vendrell, Chem. Commun., 2016, 52, 9093 DOI: 10.1039/C6CC00095A

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