Issue 6, 2015

Enzyme-responsive polymer assemblies constructed through covalent synthesis and supramolecular strategy

Abstract

Enzyme-responsive polymer assemblies have proved to be promising candidates for biomaterials, biomedicine and biosensing. Traditionally, these assemblies are prepared by the self-assembly of polymer building blocks which are covalently conjugated with enzyme-responsive moieties. Moreover, a supramolecular strategy has recently been developed for the preparation of enzyme-responsive polymer assemblies where the enzyme-responsive moieties are non-covalently complexed with the polymer building blocks. In addition, kinetic studies have been conducted on the enzyme-responsive behaviour of the polymer assemblies, which paves the way for tuning the response rate of the assemblies in a controlled manner.

Graphical abstract: Enzyme-responsive polymer assemblies constructed through covalent synthesis and supramolecular strategy

Article information

Article type
Feature Article
Submitted
29 juil. 2014
Accepted
21 oct. 2014
First published
23 oct. 2014

Chem. Commun., 2015,51, 996-1003

Enzyme-responsive polymer assemblies constructed through covalent synthesis and supramolecular strategy

Y. Ding, Y. Kang and X. Zhang, Chem. Commun., 2015, 51, 996 DOI: 10.1039/C4CC05878J

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