Issue 93, 2014

Antibacterial polymeric nanostructures for biomedical applications

Abstract

The high incidence of bacterial infection and the growing resistance of bacteria to conventional antibiotics have resulted in the strong need for the development of new generation of antibiotics. Nano-sized particles have been considered as novel antibacterial agents with high surface area and high reactivity. The overall antibacterial properties of antimicrobial nanostructures can be significantly enhanced compared with conventional antibacterial agents not in a regular nanostructure, showing a better effect in inhibiting the growth and reproduction of microbials such as bacteria and fungi, etc. In this review, recent advances in the research and applications of antimicrobial polymeric nanostructures have been highlighted, including silver-decorated polymer micelles and vesicles, antimicrobial polymer micelles and vesicles, and antimicrobial peptide-based vesicles, etc. Furthermore, we proposed the current challenges and future research directions in the field of antibacterial polymeric nanostructures for the real-world biomedical applications.

Graphical abstract: Antibacterial polymeric nanostructures for biomedical applications

Article information

Article type
Feature Article
Submitted
23 avr. 2014
Accepted
31 juil. 2014
First published
31 juil. 2014

Chem. Commun., 2014,50, 14482-14493

Author version available

Antibacterial polymeric nanostructures for biomedical applications

J. Chen, F. Wang, Q. Liu and J. Du, Chem. Commun., 2014, 50, 14482 DOI: 10.1039/C4CC03001J

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