A sustainable palladium-catalyzed vinyl epoxide cross coupling with umpolung hydrazones has been developed. This platform provides access to branched homoallylic alcohols in a regioselective manner.
This review aims to collect advancements in enantioselective palladium-catalyzed cyclization reactions over the past eleven years, and it is organized into thirteen sections depending on the different types of transformations involved.
Enantioselective cascades involving the reaction of the π-allyl complex have been a viable strategy, and further replacement of the customary allyl acetates with contemporary synthons has opened many opportunities in this escalating field.
This review provides an overview of skipped dienes synthesis in the last five years. Metal-mediated, metal-free, synergistic/dual and metallaphotoredox catalysed reactions are analysed based on catalytic system, mechanism and stereoselectivity.
The details of our total synthesis of scabrolide F are described. The synthetic scabrolide F and its synthetic intermediates exhibited antifouling activity without toxicity.