The interrupted Pummerer reaction of alkynyl sulfoxides with phenols is disclosed. The good availability of alkynyl sulfoxides and phenols enabled us to prepare various functionalized benzo[b]furans.
A one-pot, 2-step process involving the first DABSO-facilitated Pummerer reaction enables access to the 3H-pyrrolo-[2,3-c] quinolines and eventually to the marine natural products marinoquinolines A, K, and H, possessing antimalarial activity.
We report an efficient sulfoxide deoxygenation protocol that utilizes Et3N as an electron-donating reductant in combination with the activating agent SOCl2.
A novel approach for synthesizing the A-B-C-D ring system of anislactone-type sesquiterpenoids was enabled by a H2O2-mediated oxidative ring contraction reaction.
This feature article elucidates the development and notable progress of glycosyl sulfoxide-based glycosylation reactions, with a specific emphasis on cases where sulfinyl groups are situated either directly at the anomeric position or more distally.