Oral nanomedicine biointeractions in the gastrointestinal tract in health and disease

Cheng Chen, Ana Beloqui and Yining Xu

Advanced Drug Delivery Reviews, 2023, 203, 115117
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Applications of smart responsive nanomaterials in the theranostics of gastrointestinal malignancies: Current status and future perspectives

Wenpeng Huang, Jingwei Zhou, Yutong Liang, Rachel J. Saladin, Liming Li, Lei Kang, Chen Hua and Weibo Cai

Coordination Chemistry Reviews, 2025, 535, 216641
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Hybrid crystalline bioparticles with nanochannels encapsulating acemannan from Aloe vera: Structure and interaction with lipid membranes

Rafael R.M. Madrid, Patrick D. Mathews, Shreya Pramanik, Agustín Mangiarotti, Rodrigo Fernandes, Rosangela Itri, Rumiana Dimova and Omar Mertins

Journal of Colloid and Interface Science, 2024, 673, 373
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Nanoparticles, a promising treatment for gastric cancer

Di Hua, Xiexing Wu, Zebin Wu, Chunyang Fan, Jiale Wang, Wei He, Yongkang Deng, Yao Zhang, Hengxiang Shu, Meng Shen, Dechun Geng and Kai Chen

Smart Materials in Medicine, 2025, 6, 23
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Ternary lipids-based novel thermoresponsive lipid nanoparticles for targeting doxorubicin to breast cancer cells

Maryam Anwar, Mubashar Rehman, Tofeeq Ur-Rehman, Muhammad Imran Khan, Naveed Ahmed, Asadullah Madni and Muhammad Tayyab

Journal of Pharmaceutical Sciences, 2025, 114, 103723
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Antibacterial polypeptide-bioparticle for oral administration: Powder formulation, palatability and in vivo toxicity approach

Carlos A.B. Ramirez, Patrick D. Mathews, Rafael R.M. Madrid, Irene T.S. Garcia, Vera L.S. Rigoni and Omar Mertins

Biomaterials Advances, 2023, 153, 213525
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Layer-by-layer hybrid hexosomes with enhanced oxidative stability and bioaccessibility of omega-3 polyunsaturated fatty acids

Zahra Eskandari, Seyed Fakhreddin Hosseini, Gokce Dicle Kalaycioglu and Anan Yaghmur

Food Chemistry, 2025, 489, 145050
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Flavonoid-Labeled Biopolymer in the Structure of Lipid Membranes to Improve the Applicability of Antioxidant Nanovesicles

Patrick D. Mathews, Gabriella S. Gama, Hector M. Megiati, Rafael R. M. Madrid, Bianca B. M. Garcia, Sang W. Han, Rosangela Itri and Omar Mertins

Pharmaceutics, 2024, 16, 141
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Structural Effects of Multivalent Counterions in the Self-Assembly of Polyelectrolyte Copolymers

Liyan Liu, Fujia Wang, Boyi Zhang, Ting Zhang, Ying Wang and Bing Han

ACS Omega, 2025, 10, 17694
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Vitexin‐loaded poly(ethylene glycol) methyl ether‐grafted chitosan/alginate nanoparticles: preparation, physicochemical properties and in vitro release behaviors

Rangrong Yoksan and Pawika Towongphaichayonte

J Sci Food Agric, 2024, 104, 956
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Lubricated Interfaces Enabling Simultaneous Pulsatile and Continuous Chemical Release Modes

Angana Borbora, Yang Xu, Souradeep Dey, Xin Wang, Yuxing Yao, Biman B. Mandal, Xiaoguang Wang and Uttam Manna

Advanced Materials, 2023, 35
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Amphiphilic lipids for food functionality

Rafael V.M. Freire and Stefan Salentinig

Current Opinion in Colloid & Interface Science, 2024, 72, 101817
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Novel bioactive cationic cubosomes enhance the cytotoxic effect of paclitaxel against a paclitaxel resistant prostate cancer cell-line

S. Pushpa Ragini, Jacinta White, Nigel Kirby, Rajkumar Banerjee, Surendar Reddy Bathula, Calum J. Drummond and Charlotte E. Conn

Journal of Colloid and Interface Science, 2023, 649, 966
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A short review on the applicability and use of cubosomes as nanocarriers

Amanda Santos Palma, Bruna Renata Casadei, Mayra Cristina Lotierzo, Raphael Dias de Castro and Leandro Ramos Souza Barbosa

Biophys Rev, 2023, 15, 553
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Structural characterization of the lipid exchange between lipidic cubic phase nanoparticles and lipid monolayers using neutron reflectometry.

Ewa Nazaruk, Richard A. Campbell, Glenn J. Coope, M. Jayne Lawrence, Maximilian W.A. Skoda, Renata Bilewicz and Dorota Matyszewska

Journal of Colloid and Interface Science, 2026, 703, 139190
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Recent developments with pH-responsive lyotropic liquid crystalline lipid nanoparticles for targeted bioactive agent delivery

Natinael Koyra, Haitao Yu, Calum J. Drummond, Jiali Zhai and Brendan Dyett

Expert Opinion on Drug Delivery, 2025, 22, 1303
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Polyphosphoester-stabilized cubosomes encapsulating a Ru(II) complex for the photodynamic treatment of lung adenocarcinoma

Luca Casula, Gina Elena Giacomazzo, Luca Conti, Marco Fornasier, Benedetto Manca, Michele Schlich, Chiara Sinico, Timo Rheinberger, Frederik R. Wurm, Claudia Giorgi and Sergio Murgia

Journal of Colloid and Interface Science, 2024, 670, 234
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Exploring pH-Triggered Lamellar to Cubic Phase Transition in 2-Hydroxyoleic Acid/Monoolein Nanodispersions: Insights into Membrane Physicochemical Properties

Xuehui Rui, Nozomi Morishita Watanabe, Yukihiro Okamoto, Ward Wakileh and Hiroshi Umakoshi

J. Phys. Chem. B, 2024, 128, 9151
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Thermodynamic and Conformational Study on the Interaction between pH-Responsive Polymer-Shell Cubosome and Mucin for Drug Delivery Applications

Rafael R. M. Madrid, Patrick D. Mathews and Omar Mertins

ACS Appl. Polym. Mater., 2026, 8, 2846
DOI: 10.1021/acsapm.5c04369

Dynamic Self-Assembly and Stimuli-Responsive Disassembly of Bioactive-Loaded Cubosomes in Biomimetic Media Traced by Real-Time Small-Angle X-ray Scattering and Cryogenic Transmission Electron Microscopy

Rafael R.M. Madrid, Angelina Angelova, Borislav Angelov, Gouranga Manna, Patrick D. Mathews and Omar Mertins

ACS Appl. Mater. Interfaces, 2025, 17, 69118
DOI: 10.1021/acsami.5c18735