Chemically heparinized PEEK via a green method to immobilize bone morphogenetic protein-2 (BMP-2) for enhanced osteogenic activity

MeeiChyn Goh, Kiyoon Min, Young Ha Kim and Giyoong Tae

RSC Adv., 2024, 14, 1866
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Strategies to improve the performance of polyetheretherketone (PEEK) as orthopedic implants: from surface modification to addition of bioactive materials

Huagui Huang, Xin Liu, Jinzuo Wang, Moran Suo, Jing Zhang, Tianze Sun, Honghua Wang, Chengde Liu and Zhonghai Li

J. Mater. Chem. B, 2024, 12, 4533
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Mussel-inspired “built-up” surface chemistry coating on polyetheretherketone enhances osteogenic, angiogenic, and antibacterial properties for improved osseointegration

Lvhua Liu, Yongheng Zhang, Mengqi Li, Mingyuan Yang, Liping Zhou, Caiwei Zeng, Huang Zhou, Xiaoyu Zheng, Penghui Li, Huaiyu Wang and Yanyan Zheng

Colloids and Surfaces A: Physicochemical and Engineering Aspects, 2025, 726, 137760
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Using dynamic biomaterials to study the temporal role of bioactive peptides during osteogenesis

Fallon M. Fumasi, Tara MacCulloch, Julio Bernal-Chanchavac, Nicholas Stephanopoulos and Julianne L. Holloway

Biomaterials Advances, 2024, 157, 213726
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Current treatment methods to improve the bioactivity and bonding strength of PEEK for dental application: A systematic review

Tongtong Ma, Jiajia Zhang, Shuoyao Sun, Wenqing Meng, Yan Zhang and Junling Wu

European Polymer Journal, 2023, 183, 111757
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Peptidic biofunctionalization of laser patterned dental zirconia: A biochemical-topographical approach

J. Minguela, D.W. Müller, F. Mücklich, L. Llanes, M.P. Ginebra, J.J. Roa and C. Mas-Moruno

Materials Science and Engineering: C, 2021, 125, 112096
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Covalent binding modes between BMP-2-derived peptides and graphene in 3D scaffolds determine their osteoinductivity and capacity for calvarial defect repair in vivo

Zhiwei Xu, Cunyang Wang, Guiqin Song, Yan Wang, Xiaoyun Zhang and Xiaoming Li

International Journal of Biological Macromolecules, 2023, 237, 124077
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Surface chemistry on PEEK surfaces: From enhanced biofunctionality to improved surface modifiability

Peng Qiu, Vincent Bennani, Paul Cooper, George Dias and Jithendra Ratnayake

Applied Materials Today, 2024, 41, 102523
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Multifunctional surface coating using chitosan and its chemical functionalization

Sangwon Ko

Bulletin Korean Chem Soc, 2022, 43, 1207
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Reduction of mesoporous poly(ether ether ketone) materials, preserving pore size

Sagiv Weintraub, Gary Gellerman, Andrii Bazylevich and Ben Bikson

Polymer International, 2024, 73, 471
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Polyetheretherketone Double Functionalization with Bioactive Peptides Improves Human Osteoblast Response

Leonardo Cassari, Cristian Balducci, Grazia M. L. Messina, Giovanna Iucci, Chiara Battocchio, Federica Bertelà, Giovanni Lucchetta, Trevor Coward, Lucy Di Silvio, Giovanni Marletta, Annj Zamuner, Paola Brun and Monica Dettin

Biomimetics, 2024, 9, 767
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Multifunctional surface of the nano-morphic PEEK implant with enhanced angiogenic, osteogenic and antibacterial properties

Jiajia Zhang, Tongtong Ma, Xueye Liu, Xiaoran Zhang, Wenqing Meng and Junling Wu

Regenerative Biomaterials, 2024, 11
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Alendronate as Bioactive Coating on Titanium Surfaces: An Investigation of CaP–Alendronate Interactions

Ines Despotović, Željka Petrović, Jozefina Katić and Dajana Mikić

Materials, 2024, 17, 2703
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Application of biomolecules modification strategies on PEEK and its composites for osteogenesis and antibacterial properties

Xiao Han, Weijia Gao, Zhe Zhou, Shihui Yang, Junyan Wang, Ruining Shi, Yongli Li, Junjie Jiao, Yuanzheng Qi and Jinghui Zhao

Colloids and Surfaces B: Biointerfaces, 2022, 215, 112492
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Selected Spectroscopic Techniques for Surface Analysis of Dental Materials: A Narrative Review

Katarzyna Kaczmarek, Andrzej Leniart, Barbara Lapinska, Slawomira Skrzypek and Monika Lukomska-Szymanska

Materials, 2021, 14, 2624
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State-of-the-art polyetheretherketone three-dimensional printing and multifunctional modification for dental implants

Meiqing Chen, Mei Ren, Yingqi Shi, Xiuyu Liu and Hongtao Wei

Front. Bioeng. Biotechnol., 2023, 11
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Endowing implants surface with enhanced vascularization and osseointegration via presenting triple-functional peptides

Wenjie Liu, Qing Wang, Hao Liu, Suqin He, Hongxiang Wang, Chengwei Xu, Chaofan Jin, Na Li and Lianxin Li

Journal of Orthopaedic Translation, 2025, 52, 150
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Reconstruction of Surface Porous PEEK Decorated with Strontium-doped Calcium Phosphate Coatings for Enhancing Osteogenic Activity

Chengcheng Liang, Xiong Xiong, Rongwei Cui, Yuanxiao Hong, Xin Liu, Guoru Zhao, Lizi Ye and Shuxin Qu

J Bionic Eng, 2021, 18, 927
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Self-Adaptive Antibacterial Scaffold with Programmed Delivery of Osteogenic Peptide and Lysozyme for Infected Bone Defect Treatment

Luxuan Shen, Shuqin Cao, Yuemin Wang, Pei Zhou, Shuaibing Wang, Yao Zhao, Lingzhuang Meng, Quan Zhang, Yanyan Li, Xinyuan Xu, Quan Yuan and Jianshu Li

ACS Appl. Mater. Interfaces, 2023, 15, 626
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Biomechanical performance of Ti-PEEK dental implants in bone: An in-silico analysis

Abdelhak Ouldyerou, Ali Merdji, Laid Aminallah, Sandipan Roy, Hassan Mehboob and Mutlu Özcan

Journal of the Mechanical Behavior of Biomedical Materials, 2022, 134, 105422
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Peptide-Functionalized Nanomedicine: Advancements in Drug Delivery, Diagnostics, and Biomedical Applications

Hossein Omidian, Luigi X. Cubeddu and Renae L. Wilson

Molecules, 2025, 30, 1572
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Construction of multifunctional coating with cationic amino acid-coupled peptides for osseointegration of implants

Bingyang Zhao, Yilong Dong, Xinkun Shen, Wei He, Hairu Jin, Lili yao, Sheng wu Zheng, Xingjie Zan and Jiming Liu

Materials Today Bio, 2023, 23, 100848
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Engineered sonosensitive probiotics extracellular vesicles coating for ultrasound-driven anti-infection and immunoregulation in implant infection treatment

Mingyue Han, Shuoyuan Li, Wenqi Wang, Jianshu Li, Jun Luo, Zongke Zhou, Jiyao Li, Duan Wang and Jiaojiao Yang

Chemical Engineering Journal, 2025, 504, 158946
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Strategies for the Covalent Anchoring of a BMP-2-Mimetic Peptide to PEEK Surface for Bone Tissue Engineering

Leonardo Cassari, Annj Zamuner, Grazia Maria Lucia Messina, Martina Marsotto, Hao-chen Chang, Trevor Coward, Chiara Battocchio, Giovanna Iucci, Giovanni Marletta, Lucy Di Silvio and Monica Dettin

Materials, 2023, 16, 3869
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Enhancing antibacterial capability and osseointegration of polyetheretherketone (PEEK) implants by dual-functional surface modification

Chengzhe Gao, Zongliang Wang, Zixue Jiao, Zhenxu Wu, Min Guo, Yu Wang, Jianguo Liu and Peibiao Zhang

Materials & Design, 2021, 205, 109733
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Multifunctional bioactive metal phenolic networks (MPN) with copper ion retardation and dual-peptides for enhanced osteointegration

Wenjie Liu, Qing Wang, Hao Liu, Suqin He, Hongxiang Wang, Chengwei Xu, Bingyang Zhao, Chaofan Jin, Na Li and Siwang Hu

Biomaterials Advances, 2025, 177, 214388
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Bioactive PEEK: Surface Enrichment of Vitronectin-Derived Adhesive Peptides

Leonardo Cassari, Annj Zamuner, Grazia M. L. Messina, Martina Marsotto, Hongyi Chen, Giovanni Gonnella, Trevor Coward, Chiara Battocchio, Jie Huang, Giovanna Iucci, Giovanni Marletta, Lucy Di Silvio and Monica Dettin

Biomolecules, 2023, 13, 246
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Engineering tunable dual peptide hybrid coatings promote osseointegration of implants

Zeyu Shou, Zhibiao Bai, Han Zhou, Yizhe Shen, Xiaojing Huang, Hongming Meng, Chenwei Xu, Shaohao Wu, Na Li and Chun Chen

Materials Today Bio, 2024, 24, 100921
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Formation of a robust Cu adhesive layer on poly(ether ether ketone) via self UV-initiated surface polymerization

Joon Hur, Joonbum Lee, Bo-Young Kim, Myong Jae Yoo and Ji-Hun Seo

Journal of Industrial and Engineering Chemistry, 2022, 112, 307
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Porous polyetheretherketone microcarriers fabricated via hydroxylation together with cell-derived mineralized extracellular matrix coatings promote cell expansion and bone regeneration

Shuo Sun, Zixue Jiao, Yu Wang, Zhenxu Wu, Haowei Wang, Qingming Ji, Yi Liu, Zongliang Wang and Peibiao Zhang

Regenerative Biomaterials, 2021, 8
DOI: 10.1093/rb/rbab013

Solubility of N, N′-Disuccinimidyl Carbonate and its relevance to polysaccharide functionalization

Tingyu Li and David Vanderah

Analytical Biochemistry, 2021, 626, 114250
DOI: 10.1016/j.ab.2021.114250

Effect of covalent-binding modes of osteogenic-related peptides with artificial carriers on their biological activities in vivo

Cunyang Wang, Suxiang Yu, Qi Guo, Ke Zhang, Yuntao Di and Xiaoming Li

Journal of Materials Science & Technology, 2023, 140, 163
DOI: 10.1016/j.jmst.2022.08.027

Applications, modifications, and manufacturing of polyetheretherketone (PEEK) in dental implantology: A comprehensive critical review

Ahmed Yaseen Alqutaibi, Mohammed Ahmed Alghauli, Radhwan Saleh Algabri, Hatem Hazzaa Hamadallah, Afaf Noman Aboalrejal, Muhammad Sohail Zafar and Muhammad Amber Fareed

International Materials Reviews, 2025, 70, 103
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Rational integration of defense and repair synergy on PEEK osteoimplants via biomimetic peptide clicking strategy

Meng Li, Jiaxiang Bai, Huaqiang Tao, Li Hao, Weiling Yin, Xiaoxue Ren, Ang Gao, Ning Li, Miao Wang, Shiyuan Fang, Yaozeng Xu, Liang Chen, Huilin Yang, Huaiyu Wang, Guoqing Pan and Dechun Geng

Bioactive Materials, 2022, 8, 309
DOI: 10.1016/j.bioactmat.2021.07.002

Enhanced vascularization and osseointegration under osteoporotic conditions through functional peptide coating on implant surfaces

Jiming Liu, Bingyang Zhao, Xinkun Shen, Dandan Lu, Wei he, Xingjie Zan, Lianxin Li and Yihuai Pan

Materials Today Bio, 2024, 27, 101150
DOI: 10.1016/j.mtbio.2024.101150

A pH-Responsive Polyetheretherketone Implant Modified with a Core–Shell Metal–Organic Framework to Promote Antibacterial and Osseointegration Abilities

Shiqing Ma, Shiyu Yao, Yumeng Li, Yilin Yang, Tianyi Tong, Hong Zheng, Beibei Ma, Pengfei Wei, Zhengyi Di, Bo Zhao and Jiayin Deng

Biomater Res, 2025, 29
DOI: 10.34133/bmr.0188