A comprehensive and systematic review on potential anticancer activities of eugenol: From pre-clinical evidence to molecular mechanisms of action

Syeda Nurunnesa Begum, Anindya Sundar Ray and Chowdhury Habibur Rahaman

Phytomedicine, 2022, 107, 154456
DOI: 10.1016/j.phymed.2022.154456

The Nexus of Inflammation-Induced Epithelial-Mesenchymal Transition and Lung Cancer Progression: A Roadmap to Pentacyclic Triterpenoid-Based Therapies

Kirill V. Odarenko, Marina A. Zenkova and Andrey V. Markov

IJMS, 2023, 24, 17325
DOI: 10.3390/ijms242417325

Molecular Mechanisms of Action of Eugenol in Cancer: Recent Trends and Advancement

Ipsa Padhy, Paramita Paul, Tripti Sharma, Sabyasachi Banerjee and Arijit Mondal

Life, 2022, 12, 1795
DOI: 10.3390/life12111795

Cetuximab-conjugated PLGA nanoparticles as a prospective targeting therapeutics for non-small cell lung cancer

Leena Kumari, Iman Ehsan, Arunima Mondal, Ashique Al Hoque, Biswajit Mukherjee, Pritha Choudhury, Arunima Sengupta, Ramkrishna Sen and Prasanta Ghosh

Journal of Drug Targeting, 2023, 31, 521
DOI: 10.1080/1061186X.2023.2199350

Eugenol suppresses VEGF-dependent angiogenesis by JAK2/STAT3 pathway in non-small cell lung cancer

Yifan Su, Yurong Wang, Qian Yu, Zhijian Wu, Dawei Zhang and Chunyan Yan

Guidelines and Standards of Chinese Medicine, 2024, 2, 80
DOI: 10.1097/gscm.0000000000000021

The Effect of Aerobic Exercise Training and Eugenol Supplementation on the Wnt, TGF-β, and Beta-Catenin gene Expression in Myocardial Tissue of Poisoned Rats Induced by Chlorpyrifos

Fatemeh Parsa-Lisar, Hasan Matinhomaei and Mohammad Ali Azarbayjani

Thrita, 2022, 11
DOI: 10.5812/thrita-118263

Anticancer Properties of Eugenol: A Review

Ali T. Zari, Talal A. Zari and Khalid Rehman Hakeem

Molecules, 2021, 26, 7407
DOI: 10.3390/molecules26237407

Targeting Cancer Stem Cells by Natural Compounds in Combination with Conventional Chemotherapy: An Ideal Strategy for Combating Cancer Recurrence

Rituparna Ghosh, Souradeep Biswas, Priya Samanta, Rupali Sarkar, Shampa Pakhira, Mrinmoyee Mondal, Arijit Bhowmik, Subhadip Hajra and Prosenjit Saha

Journal of Current Oncological Trends, 2024, 1, 14
DOI: 10.4103/JCOT.JCOT_9_23

Natural compounds: Wnt pathway inhibitors with therapeutic potential in lung cancer

Xuetong Shen, Chundi Gao, Huayao Li, Cun Liu, Longyun Wang, Ye Li, Ruijuan Liu, Changgang Sun and Jing Zhuang

Front. Pharmacol., 2023, 14
DOI: 10.3389/fphar.2023.1250893

Molecular mechanisms of eugenol as an antitumour bioactive compound: A comprehensive review

Shukrya Alwan, Tamara Hatem, Hussein Abid, X. Feng and M. Khondker

BIO Web Conf., 2024, 125, 03007
DOI: 10.1051/bioconf/202412503007

CK1α deficiency impairs mouse uterine adenogenesis by inducing epithelial cell apoptosis through GSK3β pathway and inhibiting Foxa2 expression through p53 pathway

Di Zhang, Chenyang Lu, Yewen Zhou, Xuan Luo, Hongzhou Guo, Jinglin Zhang, Qiao Gao, Hui Liu, Chongxing Shang and Sheng Cui

Biology of Reproduction, 2024, 110, 246
DOI: 10.1093/biolre/ioad144

From Natural Sources to Synthetic Derivatives: The Allyl Motif as a Powerful Tool for Fragment-Based Design in Cancer Treatment

Nora Astrain-Redin, Carmen Sanmartin, Arun K. Sharma and Daniel Plano

J. Med. Chem., 2023, 66, 3703
DOI: 10.1021/acs.jmedchem.2c01406

The anticarcinogenic effect of eugenol on lung cancer induced by diethylnitrosamine/2-acetylaminofluorene in Wistar rats: insight on the mechanisms of action

Hadeer M. Morsy, Osama M. Ahmed, Khairy M. A. Zoheir and Adel Abdel-Moneim

Apoptosis, 2023, 28, 1184
DOI: 10.1007/s10495-023-01852-2

The recent update and advancements of natural products in targeting the Wnt/β-Catenin pathway for cancer prevention and therapeutics

Lunasmrita Saikia, Bhaskarjyoti Gogoi, Saikat Sen, Rajiv K. Tonk, Deepak Kumar and Partha Pratim Dutta

Med Oncol, 2024, 41
DOI: 10.1007/s12032-024-02387-5

An Update on the Therapeutic Anticancer Potential of Ocimum sanctum L.: “Elixir of Life”

Mohammad Raghibul Hasan, Bader Saud Alotaibi, Ziyad Mohammed Althafar, Ahmed Hussain Mujamammi and Jafar Jameela

Molecules, 2023, 28, 1193
DOI: 10.3390/molecules28031193

Eugenol’s anti-cancer properties, its modulation of signalling pathways, and cascades across various cancers: A review

Anirban Debnath, Yi-Hao Lo, Manojit Bhattacharya, Zhi-Hong Wen, Chiranjib Chakraborty and Arpita Das

Current Research in Biotechnology, 2025, 10, 100330
DOI: 10.1016/j.crbiot.2025.100330

Anticancer potentials of bioactive compounds in some locally available spices in Nigeria

Emmanuel Saviour Saheed

Discov. Plants, 2024, 1
DOI: 10.1007/s44372-024-00059-2

Natural Products, Alone or in Combination with FDA-Approved Drugs, to Treat COVID-19 and Lung Cancer

Liyan Yang and Zhonglei Wang

Biomedicines, 2021, 9, 689
DOI: 10.3390/biomedicines9060689

Molecular Insights on Coffee Components as Chemical Antioxidants

Luis Felipe Hernández-Ayala, Eduardo Gabriel Guzmán-López, Adriana Pérez-González, Miguel Reina and Annia Galano

J. Mex. Chem. Soc., 2024, 68, 888
DOI: 10.29356/jmcs.v68i4.2238

Eugenol: An Insight Into the Anticancer Perspective and Pharmacological Aspects

Ahmad Mujtaba Noman, Muhammad Tauseef Sultan, Aimen Mazhar, Waqas Ahmad Khan, Muhammad Imran, Muzzamal Hussain, Ehab M. Mostafa, Ahmed H. El‐Ghorab, Mohammed M. Ghoneim, Samy Selim, Mohamed A. Abdelgawad, Entessar Al Jbawi, Suliman A. Alsagaby and Waleed Al Abdulmonem

Food Science & Nutrition, 2025, 13
DOI: 10.1002/fsn3.70727

Research Progress on Antitumor Effects of Active Components of Clove

振伟秦

ACM, 2023, 13, 6826
DOI: 10.12677/ACM.2023.134955

Research on the mechanism of eugenol in the treatment of liver cancer based on network pharmacology, molecular docking technology, and in vitro experiments

Kaiping Liu, Jiuliang Jiang, Zhenyu Yu, Yunhao Wang, Min Wang and Haitao Zhu

Anti-Cancer Drugs, 2025, 36, 177
DOI: 10.1097/CAD.0000000000001675

In silico molecular docking and dynamic simulation of eugenol compounds against breast cancer

Hezha O. Rasul, Bakhtyar K. Aziz, Dlzar D. Ghafour and Arif Kivrak

J Mol Model, 2022, 28
DOI: 10.1007/s00894-021-05010-w

Targeting cancer stem cell pathways for lung cancer therapy

Mingxin Liu, Hong Wu and Chuan Xu

Current Opinion in Oncology, 2023, 35, 78
DOI: 10.1097/CCO.0000000000000912