Does addition of 1-octanol as a phase modifier provide radical scavenging radioprotection for N,N,N′,N′-tetraoctyldiglycolamide (TODGA)?

Gregory P. Horne, Christopher A. Zarzana, Cathy Rae, Andrew R. Cook, Stephen P. Mezyk, Peter R. Zalupski, Andreas Wilden and Bruce J. Mincher

Phys. Chem. Chem. Phys., 2020, 22, 24978
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Effect off-element complexation on the radiolysis of 2-ethylhexylphosphonic acid mono-2-ethylhexyl ester (HEH[EHP])

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Gamma radiolysis of hydrophilic diglycolamide ligands in concentrated aqueous nitrate solution

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Dalton Trans., 2019, 48, 17005
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An experimental and computational look at the radiolytic degradation of TODGA and the effect on metal complexation

Ashleigh Kimberlin, Dominique Guillaumont, Sylvie Arpigny, Béatrice Camès, Philippe Guilbaud, Georges Saint-Louis, Hitos Galán and Laurence Berthon

New J. Chem., 2021, 45, 12479
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31P NMR study of the activated radioprotection mechanism of octylphenyl-N,N-diisobutylcarbamoylmethyl phosphine oxide (CMPO) and analogues

Gregory P. Horne, James J. Kiddle, Christopher A. Zarzana, Cathy Rae, Julie R. Peller, Andrew R. Cook, Stephen P. Mezyk and Bruce J. Mincher

Dalton Trans., 2019, 48, 11547
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A search of a quantitative quantum-chemical approach for radiolytic stability prediction

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Phys. Chem. Chem. Phys., 2020, 22, 14992
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Impact of lanthanide ion complexation and temperature on the chemical reactivity of N,N,N′,N′-tetraoctyl diglycolamide (TODGA) with the dodecane radical cation

Gregory P. Horne, Cristian Celis-Barros, Jacy K. Conrad, Travis S. Grimes, Jeffrey R. McLachlan, Brian M. Rotermund, Andrew R. Cook and Stephen P. Mezyk

Phys. Chem. Chem. Phys., 2023, 25, 16404
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Testing a simple approach for theoretical evaluation of radiolysis products in extraction systems. A case of N,O-donor ligands for Am/Eu separation

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RSC Adv., 2017, 7, 55441
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Effect of metal complexation on diglycolamide radiolysis: a comparison between ex situ gamma and in situ alpha irradiation

Ashleigh Kimberlin, Georges Saint-Louis, Dominique Guillaumont, Béatrice Camès, Philippe Guilbaud and Laurence Berthon

Phys. Chem. Chem. Phys., 2022, 24, 9213
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Ligands for f-element extraction used in the nuclear fuel cycle

Andrea Leoncini, Jurriaan Huskens and Willem Verboom

Chem. Soc. Rev., 2017, 46, 7229
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Synthesis and evaluation of new modified diglycolamides with different stereochemistry for extraction of tri- and tetravalent metal ions

Laura Diaz Gomez, Andreas Wilden, Dimitri Schneider, Zaina Paparigas, Giuseppe Modolo, Maria Chiara Gullo, Jurriaan Huskens and Willem Verboom

New J. Chem., 2023, 47, 4619
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Evaluation of the Arrhenius behavior of n-dodecane radical cation (RH˙+) reactivity with lanthanide ion-complexed N,N,N′,N′-tetraoctyl diglycolamide (TODGA)

Maya H. Rogalski, Anh N. Dang and Stephen P. Mezyk

Phys. Chem. Chem. Phys., 2025, 27, 1960
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γ-Radiation effect on Th4+ extraction behaviour of TODGA/[C2mim][NTf2]: identification and extractability study of radiolytic products

Weijin Yuan, Congzhi Wang, Yinyong Ao, Long Zhao, Weiqun Shi and Maolin Zhai

RSC Adv., 2016, 6, 7626
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Ultrafast pre-solvated dodecane hole capture and subsequent damage of used nuclear fuel extraction ligands DEHBA, DEHiBA, HONTA, CMPO, HEH[EHP] and TBP

Rupali G. Deokar and Andrew R. Cook

Phys. Chem. Chem. Phys., 2025, 27, 8110
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Behaviour of the extractant Me-TODGA upon gamma irradiation: quantification of degradation compounds and individual influences on complexation and extraction

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New J. Chem., 2017, 41, 13700
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Gamma radiolytic stability of the novel modified diglycolamide 2,2′-oxybis(N,N-didecylpropanamide) (mTDDGA) for grouped actinide extraction

Bart Verlinden, Karen Van Hecke, Andreas Wilden, Michelle Hupert, Beatrix Santiago-Schübel, Richard J. M. Egberink, Willem Verboom, Piotr M. Kowalski, Giuseppe Modolo, Marc Verwerft, Koen Binnemans and Thomas Cardinaels

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Early-stage oxidation and subsequent damage of the used nuclear fuel extractant TODGA; electron pulse radiolysis and theoretical insights

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Phys. Chem. Chem. Phys., 2024, 26, 29060
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Impacts of molecular architecture on the radiation-induced degradation and reaction kinetics of hydrophobic diglycolamides with the solvated electron and the dodecane radical cation

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Phys. Chem. Chem. Phys., 2025, 27, 16254
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Radiolytic stability and effects on metal extraction of N,N,N′-trioctyldiglycolamide, an important TODGA degradation product

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New J. Chem., 2024, 48, 2087
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First-principles study of the radiolytic degradation of diglycolamides

Bart Verlinden, Karen Van Hecke, Andreas Wilden, Giuseppe Modolo, Koen Binnemans, Thomas Cardinaels and Piotr M. Kowalski

Radiochimica Acta, 2023, 111, 741
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Low and High LET Degradation Studies of Metal-Loaded Organic Phase Ligands in the ALSEP Process

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Solvent Extraction and Ion Exchange, 2023, 41, 449
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Synthesis, investigation of the structure and physico-chemical properties of modified solid-phase extractants (SPE) based on N,N,N’,N’-tetraoctyldiglycolamide (TODGA)

Aleksandr A. Savelev and Valeriy I. Rachkov

NUCET, 2025, 11, 105
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Preparation of pyrrolidinyl diglycolamide bonded silica particles and its rare earth separation properties

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Journal of Chromatography A, 2022, 1681, 463396
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Dosimetry and methodology of gamma irradiation for degradation studies on solvent extraction systems

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Radiochimica Acta, 2021, 109, 61
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Radiolytic stability of pillar[5]arene-based diglycolamides

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Radiochimica Acta, 2020, 108, 889
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Radiation chemistry of the branched-chain monoamide di-2-ethylhexyl-isobutyramide

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Solvent Extraction and Ion Exchange, 2017, 35, 480
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Solvent Optimization Studies for a New EURO-GANEX Process with 2,2’-Oxybis(N,N-di-n-decylpropanamide) (mTDDGA) and Its Radiolysis Products

Bart Verlinden, Andreas Wilden, Karen Van Hecke, Richard J. M. Egberink, Jurriaan Huskens, Willem Verboom, Michelle Hupert, Patrik Weßling, Andreas Geist, Petra J. Panak, Rainier Hermans, Marc Verwerft, Giuseppe Modolo, Koen Binnemans and Thomas Cardinaels

Solvent Extraction and Ion Exchange, 2023, 41, 59
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Actinide–lanthanide co-extraction by rigidified diglycolamides

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Solvent Extraction and Ion Exchange, 2018, 36, 41
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Radical degradation stability of ether linkage in N,N,N′,N′ -tetraoctyldiglycolamide and related organic extractants: A density functional study

Tomáš Koubský, Jaroslava Fojtíková and Ladislav Kalvoda

Progress in Nuclear Energy, 2017, 94, 208
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The SACSESS Hydrometallurgy Domain — An Overview

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Procedia Chemistry, 2016, 21, 218
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Interinstitutional Study of the New EURO-GANEX Process Resistance by Gamma Irradiation Test Loops

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Ind. Eng. Chem. Res., 2023, 62, 20326
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DFT Prediction of Radiolytic Stability of Conformationally Flexible Ligands

Anastasiia Smirnova, Maksim Yablonskiy, Vladimir Petrov and Artem Mitrofanov

Energies, 2022, 16, 257
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Application of diglycolamide extractant in rare-earth extraction

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Australian Journal of Chemistry, 2024, 77
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Gamma radiolysis studies of N,N-dioctyl-2-hydroxyacetamide: Complexation effect on the stability and implications on the hydrometallurgical extraction performance

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Radiation Physics and Chemistry, 2024, 214, 111299
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Radiation stability of diglycolamide functionalized calix[4]arenes in ionic liquid: Solvent extraction, EPR and GC–MS studies

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Separation and Purification Technology, 2016, 162, 77
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Radiolysis of diamide phenanthroline extractant: exploring the mechanism of HNO3 enhancing the extraction and An/Ln separation performance after irradiation

Yizhi Chen, Peng Zhang, Xiaofan Yang, Qiqi Guo, Hanqin Weng, Hanbao Chong, Weiqun Shi and Mingzhang Lin

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Effect of radiolysis of TODGA on the extraction of TODGA/n-dodecane toward Eu(III): an experimental and DFT study

Hang Zhang, Yin-Yong Ao, Yue Wang, Shang-Jie Zhao, Jia-Yang Sun, Mao-Lin Zhai, Jiu-Qiang Li, Jing Peng and Hui-Bo Li

NUCL SCI TECH, 2023, 34
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A Study of the γ-Radiolysis ofN,N-Didodecyl-N′,N′-Dioctyldiglycolamide Using UHPLC-ESI-MS Analysis

Kristyn M. Roscioli-Johnson, Christopher A. Zarzana, Gary S. Groenewold, Bruce J. Mincher, Andreas Wilden, Holger Schmidt, Giuseppe Modolo and Beatrix Santiago-Schübel

Solvent Extraction and Ion Exchange, 2016, 34, 439
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Performance of an i-SANEX System Based on a Water-Soluble BTP under Continuous Irradiation in a γ-Radiolysis Test Loop

Dean Peterman, Andreas Geist, Bruce Mincher, Giuseppe Modolo, Maria Hitos Galán, Lonnie Olson and Rocklan McDowell

Ind. Eng. Chem. Res., 2016, 55, 10427
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Application of quantum mechanical simulations for studying the radiolytic stability of prospective extractants in the nuclear fuel cycle

Tomáš Koubský and Jakub Luštinec

J Radioanal Nucl Chem, 2018, 318, 2407
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Ab-initio evaluation of acid influence on chemical stability of hydrophilic diglycolamides

Jakub Luštinec, Tomáš Koubský and Ladislav Kalvoda

Front. Mol. Biosci., 2022, 9
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The effects of radiation chemistry on radiochemistry: when unpaired electrons defy great expectations

Bruce J. Mincher

J Radioanal Nucl Chem, 2018, 316, 799
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Effect of Europium Complexation on N,N,N′,N′-Tetraoctyldiglycolamide Degradation Against Gamma Radiation

Iván Sánchez-García and Hitos Galán

Arab J Sci Eng, 2025, 50, 3145
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Hydrophilic Clicked 2,6-Bis-triazolyl-pyridines Endowed with High Actinide Selectivity and Radiochemical Stability: Toward a Closed Nuclear Fuel Cycle

Elena Macerata, Eros Mossini, Stefano Scaravaggi, Mario Mariani, Andrea Mele, Walter Panzeri, Nathalie Boubals, Laurence Berthon, Marie-Christine Charbonnel, Francesco Sansone, Arturo Arduini and Alessandro Casnati

J. Am. Chem. Soc., 2016, 138, 7232
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Gamma Radiolysis of TODGA and CyMe4BTPhen in the Ionic Liquid Tri-n-Octylmethylammonium Nitrate

Peter Zsabka, Karen Van Hecke, Andreas Wilden, Giuseppe Modolo, Michelle Hupert, Vincent Jespers, Stefan Voorspoels, Marc Verwerft, Koen Binnemans and Thomas Cardinaels

Solvent Extraction and Ion Exchange, 2020, 38, 212
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An overview of solvent extraction processes developed in Europe for advanced nuclear fuel recycling, Part 2 — homogeneous recycling

Thea Lyseid Authen, Jean-Marc Adnet, Stéphane Bourg, Michael Carrott, Christian Ekberg, Hitos Galán, Andreas Geist, Philippe Guilbaud, Manuel Miguirditchian, Giuseppe Modolo, Chris Rhodes, Andreas Wilden and Robin Taylor

Separation Science and Technology, 2022, 57, 1724
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Gamma Radiolysis of Phenyl-Substituted TODGAs: Part II

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Solvent Extraction and Ion Exchange, 2023, 41, 582
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Selective actinide(III) separation using 2,6-bis[1-(propan-1-ol)-1,2,3-triazol-4-yl]pyridine (PyTri-Diol) in the innovative-SANEX process: laboratory scale counter current centrifugal contactor demonstration

Andreas Wilden, Dimitri Schneider, Zaina Paparigas, Maximilian Henkes, Fabian Kreft, Andreas Geist, Eros Mossini, Elena Macerata, Mario Mariani, Maria Chiara Gullo, Alessandro Casnati and Giuseppe Modolo

Radiochimica Acta, 2022, 110, 515
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The α-radiolysis behavior and mechanism of tri-isoamyl phosphate (TiAP): New insights from 4He2+ beam irradiation experiments and theoretical calculations

Shilong Shi, Yaoshuang Wan, Guofeng Qu, Runyu Zhang, Jiajian Song, Xuanhao Huang, Jijun Yang, Zhihui Li, Tu Lan, Songdong Ding, Yuanyou Yang, Jiali Liao, Wen Feng, Jing Peng and Ning Liu

Progress in Nuclear Energy, 2026, 193, 106233
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Hydrophilic Sulfonated 2,9-Diamide-1,10-phenanthroline Endowed with a Highly Effective Ligand for Separation of Americium(III) from Europium(III): Extraction, Spectroscopy, and Density Functional Theory Calculations

Peng Ren, Pin-wen Huang, Xiao-fan Yang, Yao Zou, Wu-qing Tao, Su-liang Yang, Yun-hai Liu, Qun-yan Wu, Li-yong Yuan, Zhi-fang Chai and Wei-qun Shi

Inorg. Chem., 2021, 60, 357
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Radiolytic and hydrolytic degradation of the hydrophilic diglycolamides

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Gamma Radiolysis of Phenyl-Substituted TODGAs: Part I

Christopher A. Zarzana, Jack McAlpine, Andreas Wilden, Michelle Hupert, Andrea Stärk, Mudassir Iqbal, Willem Verboom, Bruce J. Mincher, Gary S. Groenewold and Giuseppe Modolo

Solvent Extraction and Ion Exchange, 2023, 41, 564
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Dioctyl ether radiolysis under used nuclear fuel reprocessing conditions: Foundational knowledge for the development of sacrificial ligand grafts

Gregory P. Horne, Ryan P. Morco, Andrew R. Cook and Stephen P. Mezyk

Radiation Physics and Chemistry, 2023, 213, 111217
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Solvent Extraction Systems for Separation of An(III) and Ln(III): Overview of Static and Dynamic Tests

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Moscow Univ. Chem. Bull., 2021, 76, 287
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Unprecedented Inversion of Selectivity and Extraordinary Difference in the Complexation of Trivalent f Elements by Diastereomers of a Methylated Diglycolamide

Andreas Wilden, Piotr M. Kowalski, Larissa Klaß, Benjamin Kraus, Fabian Kreft, Giuseppe Modolo, Yan Li, Jörg Rothe, Kathy Dardenne, Andreas Geist, Andrea Leoncini, Jurriaan Huskens and Willem Verboom

Chemistry A European J, 2019, 25, 5507
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Radiolytic degradation of hydrophilic PyTri ligands for minor actinide recycling

Eros Mossini, Elena Macerata, Luigi Brambilla, Walter Panzeri, Andrea Mele, Chiara Castiglioni and Mario Mariani

J Radioanal Nucl Chem, 2019, 322, 1663
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Influence of the gamma source on the radiolytic stability of N,N,N′,N′-tetra-n-octyl-diglycolamide (TODGA)

Ken Verguts, Karen Van Hecke, Jan Jordens, Stefan Voorspoels and Thomas Cardinaels

Radiochimica Acta, 2025, 113, 125
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