Yunan Zhang, Dajun Zhang, Yu Zhang, Lixin Liu, Xuesong Zhang, Lei Zhang, Yunjie Zhang, Liang Chang, Qiushuang Fan, Yongbiao Zhang, Jiaming Xi and Qiang Zhang

New J. Chem., 2017, 41, 13268
DOI: 10.1039/C7NJ02423A

Synthesis of functionalized 1-aminoisoquinolines through cascade three-component reaction of ortho-alkynylbenzaldoximes, 2H-azirines, and electrophiles

Reyhaneh Hosseinijei, Hossein Zahedian Tejeneki, Ali Nikbakht, Frank Rominger and Saeed Balalaie

Org. Biomol. Chem., 2022, 20, 3076
DOI: 10.1039/D2OB00275B

Redox-neutral functionalization of α-Csp3–H bonds of secondary cyclic amines: a highly atom-economical strategy forN-arylation/formal cross-dehydrogenative couplings

Priyankar Jha, Saddam Husen and Ravindra Kumar

Green Chem., 2021, 23, 2950
DOI: 10.1039/D0GC04258G

Haber-independent, diversity-oriented synthesis of nitrogen compounds from biorenewable chitin

Thuy Trang Pham, Xi Chen, Tilo Söhnel, Ning Yan and Jonathan Sperry

Green Chem., 2020, 22, 1978
DOI: 10.1039/D0GC00208A

Synthesis and fluorescent properties of boroisoquinolines, a new family of fluorophores

Dénes Sóvári, Attila Kormos, Orsolya Demeter, András Dancsó, György Miklós Keserű, Mátyás Milen and Péter Ábrányi-Balogh

RSC Adv., 2018, 8, 38598
DOI: 10.1039/C8RA08241C

Lauraceae alkaloids

Dayana Lacerda Custódio and Valdir Florêncio da Veiga Junior

RSC Adv., 2014, 4, 21864
DOI: 10.1039/C4RA01904K

Hybrid isoquinolines from Thalictrum foetidum: a new type of aporphine inhibiting Staphylococcus aureus by combined mechanisms

Cai-Feng Ding, Rong-Ping Zhang, Hao-Fei Yu, Jing Yang, Xu-Jie Qin, Zhi Dai, Ya-Ping Liu, Qiu-Min Lu, Ren Lai and Xiao-Dong Luo

Org. Chem. Front., 2019, 6, 3428
DOI: 10.1039/C9QO00737G

Cross-dehydrogenative C(sp3)–C(sp3) coupling via C–H activation using magnetically retrievable ruthenium-based photoredox nanocatalyst under aerobic conditions

Pooja Rana, Rashmi Gaur, Radhika Gupta, Gunjan Arora, A. Jayashree and Rakesh Kumar Sharma

Chem. Commun., 2019, 55, 7402
DOI: 10.1039/C9CC02386K

Phosphine catalysed (5 + 1) annulation of ynone/cinnamates with primary amines

Jhi Ametovski, Uttam Dutta, Laura Burchill, Debabrata Maiti, David W. Lupton and Joel F. Hooper

Chem. Commun., 2017, 53, 13071
DOI: 10.1039/C7CC08252E

Assembly of multicyclic isoquinoline scaffolds from pyridines: formal total synthesis of fredericamycin A

Fang-Xin Wang, Jia-Lei Yan, Zhixin Liu, Tingshun Zhu, Yingguo Liu, Shi-Chao Ren, Wen-Xin Lv, Zhichao Jin and Yonggui Robin Chi

Chem. Sci., 2021, 12, 10259
DOI: 10.1039/D1SC02442F

One-pot assembly of functionalized (m-terphenyl-4'-yl)isoquinolines from 1-methylisoquinoline and electrophilic acylacetylenes

Kseniya Vasil'evna Belyaeva, Lina P Nikitina, Veronika S Saliy, Andrei Valer'evich Afonin, Igor Alekseevich Ushakov, Alexander Valentinovich Vashchenko and Boris Aleksandrovich Trofimov

Mendeleev Communications, 2025, 35, 457
DOI: 10.71267/mencom.7695

Diastereoselective Synthesis of Coumarin‐Based Fused Heterocycles via Intramolecular Diels‐Alder and 1,3‐Dipolar Cycloaddition Reactions

Abdolali Alizadeh, Behnaz Farajpour, Kaveh Amir Ashjaee Asalemi and Sajad Taghipour

ChemistrySelect, 2020, 5, 9834
DOI: 10.1002/slct.202002747

Investigation of fragmentation behaviours of isoquinoline alkaloids by mass spectrometry combined with computational chemistry

Zhixing Qing, Yuqin Xu, Liuyi Yu, Jinghong Liu, Xiuqiong Huang, Zhaoshan Tang, Pi Cheng and Jianguo Zeng

Sci Rep, 2020, 10
DOI: 10.1038/s41598-019-57406-7

Can Isoquinoline Alkaloids Affect Platelet Aggregation in Whole Human Blood?

Mst Shamima Parvin, Marcel Hrubša, Jaka Fadraersada, Alejandro Carazo, Jana Karlíčková, Lucie Cahlíková, Jakub Chlebek, Kateřina Macáková and Přemysl Mladěnka

Toxins, 2022, 14, 491
DOI: 10.3390/toxins14070491

Cholinesterase inhibitory alkaloids from the rhizomes of Coptis chinensis

Thao Quyen Cao, Quynh-Mai Thi Ngo, Su Hui Seong, Ui Joung Youn, Jeong Ah Kim, Junheon Kim, Jin-Cheol Kim, Mi Hee Woo, Jae Sue Choi and Byung Sun Min

Bioorganic Chemistry, 2018, 77, 625
DOI: 10.1016/j.bioorg.2018.01.038

DNA Duplex Engineering for Enantioselective Fluorescent Sensor

Yuehua Hu, Fan Lin, Tao Wu, Yufeng Zhou, Qiusha Li, Yong Shao and Zhiai Xu

Anal. Chem., 2017, 89, 2181
DOI: 10.1021/acs.analchem.6b04709

Identification of protoberberine alkaloids as novel histone methyltransferase G9a inhibitors by structure-based virtual screening

Jie Chen, Xiao Lin, Kyoung Jin Park, Kang Ro Lee and Hyun-Ju Park

J Comput Aided Mol Des, 2018, 32, 917
DOI: 10.1007/s10822-018-0156-4

Organocatalytic Atroposelective Synthesis of Isoquinolines via Dynamic Kinetic Resolution

Ahreum Kim, Junsoo Moon, Chanhee Lee, Jayoung Song, Jongchan Kim and Yongseok Kwon

Org. Lett., 2022, 24, 1077
DOI: 10.1021/acs.orglett.1c04330

Amaryllidaceae Alkaloids of Belladine-Type from Narcissus pseudonarcissus cv. Carlton as New Selective Inhibitors of Butyrylcholinesterase

Abdullah Al Mamun, Jana Maříková, Daniela Hulcová, Jiří Janoušek, Marcela Šafratová, Lucie Nováková, Tomáš Kučera, Martina Hrabinová, Jiří Kuneš, Jan Korábečný and Lucie Cahlíková

Biomolecules, 2020, 10, 800
DOI: 10.3390/biom10050800

Anti-cholinergic activities of Turkish Corydalis DC. species

Mehtap Kilic, Bilge Sener and Erdal Kaya

Phytochemistry Letters, 2021, 45, 142
DOI: 10.1016/j.phytol.2021.08.006

Total synthesis of penipanoid C, 2-(4-hydroxybenzyl)quinazolin-4(3H)-one and NU1025

Suman Kr Ghosh and Rajagopal Nagarajan

Tetrahedron Letters, 2016, 57, 4277
DOI: 10.1016/j.tetlet.2016.08.018

Investigation on the Stereoselective Construction of Fused-Ring Frameworks by Using Photochemical Properties of N-Heteroaromatic Compounds

Noriyoshi Arai

J. Synth. Org. Chem. Jpn., 2024, 82, 234
DOI: 10.5059/yukigoseikyokaishi.82.234

Adlumiceine methyl ester, a new alkaloid from Fumaria vaillantii

Milad Iranshahy, Hamideh Javidi-Shirazi, Ngoc B. Pham, Ronald J. Quinn, Hamid Sadeghian and Mehrdad Iranshahi

Journal of Asian Natural Products Research, 2014, 16, 1148
DOI: 10.1080/10286020.2014.969717

Biologically active isoquinoline alkaloids covering 2014–2018

Xiao‐Fei Shang, Cheng‐Jie Yang, Susan L. Morris‐Natschke, Jun‐Cai Li, Xiao‐Dan Yin, Ying‐Qian Liu, Xiao Guo, Jing‐Wen Peng, Masuo Goto, Ji‐Yu Zhang and Kuo‐Hsiung Lee

Medicinal Research Reviews, 2020, 40, 2212
DOI: 10.1002/med.21703

Different structures of berberine and five other protoberberine alkaloids that affect P-glycoprotein-mediated efflux capacity

Yi-ting Zhang, Yu-qi Yu, Xiao-xia Yan, Wen-jie Wang, Xiao-ting Tian, Le Wang, Wei-liang Zhu, Li-kun Gong and Guo-yu Pan

Acta Pharmacol Sin, 2019, 40, 133
DOI: 10.1038/s41401-018-0183-7

Natural isoquinoline alkaloids: Pharmacological features and multi-target potential for complex diseases

Erika Plazas, Mónica C. Avila M, Diego R. Muñoz and Luis E. Cuca S

Pharmacological Research, 2022, 177, 106126
DOI: 10.1016/j.phrs.2022.106126

Coralyne induced self-structure in polyadenylic acid: Thermodynamics of the structural reorganization

Anirban Basu and Gopinatha Suresh Kumar

The Journal of Chemical Thermodynamics, 2016, 101, 221
DOI: 10.1016/j.jct.2016.06.002

Anti-inflammatory, Anti-bacterial and Anti-acetylcholinesterase Activities of two Isoquinoline Alkaloids–Scoulerine and Cheilanthifoline

Phurpa Wangchuk, Thanapat Sastraruji, Malai Taweechotipatr, Paul A Keller and Stephen G Pyne

Natural Product Communications, 2016, 11
DOI: 10.1177/1934578X1601101207

Hypepontine, a new quaternary alkaloid with antimicrobial properties

Tsvetelina Doncheva, Nadezhda Kostova, Violeta Valcheva, Radostina Toshkovska, Vassil Vutov and Stefan Philipov

Natural Product Research, 2020, 34, 668
DOI: 10.1080/14786419.2018.1495640

Alkaloids from Corydalis decumbens modulate neuronal excitability

Chun-Lei Zhang, Qi-Long Huang, Qian Zhu, Jing He, Juan Chen, Fan Zhang and Zheng-Yu Cao

Bioorganic Chemistry, 2020, 99, 103795
DOI: 10.1016/j.bioorg.2020.103795

Comprehensive analysis of the phytochemicals, antioxidant, antibacterial and mosquitocidal activities in Canthium coromandelicum (Burm.f.) Alston

Murugaiyan Annathurai, Sabapathy Vijayakumar, Palanivel Vanishree and Shanmugasundaram Somu

Pharmacological Research - Natural Products, 2025, 8, 100309
DOI: 10.1016/j.prenap.2025.100309

Cu(OAc)2.H2O Catalyzed C − H/C − N Bond Functionalization for the Synthesis of Isoquinoline Derivatives as Potential Antifungal Agent

Vikas B. Suryawanshi, Abhay S. Bondge, Jairaj K. Dawle and Sushil R. Mathapati

Polycyclic Aromatic Compounds, 2022, 42, 4404
DOI: 10.1080/10406638.2021.1892777

The antithrombotic, anticoagulant activity and toxicity research of ambinine, an alkaloid from the tuber of Corydalis ambigua var. amurensis

Sheng Chang, Zhiyou Yang, Na Han, Zhihui Liu and Jun Yin

Regulatory Toxicology and Pharmacology, 2018, 95, 175
DOI: 10.1016/j.yrtph.2018.03.004

tert-Butyl Nitrite Mediated Synthesis of 1,2,4-Oxadiazol-5(4H)-ones from Terminal Aryl Alkenes

Prasenjit Sau, Amitava Rakshit, Tipu Alam, Hemant Kumar Srivastava and Bhisma K. Patel

Org. Lett., 2019, 21, 4966
DOI: 10.1021/acs.orglett.9b01430

Mucroniferanines A–G, Isoquinoline Alkaloids from Corydalis mucronifera

Jun Zhang, Qing-Ying Zhang, Peng-Fei Tu, Fu-Chun Xu and Hong Liang

J. Nat. Prod., 2018, 81, 364
DOI: 10.1021/acs.jnatprod.7b00847

Isoquinolines from Corydalis tomentella from Tibet, China, possess hepatoprotective activities

Yingjiao Wang, Dandan Wang, Jianhua Zhang, Dan Liu, Zihao Wang and Dali Meng

Phytochemistry, 2018, 155, 93
DOI: 10.1016/j.phytochem.2018.07.010

Corydalis hendersonii Hemsl. protects against myocardial injury by attenuating inflammation and fibrosis via NF-κB and JAK2-STAT3 signaling pathways

Ruifeng Bai, Xu Yin, Xiao Feng, Yuan Cao, Yan Wu, Zhixiang Zhu, Chun Li, Pengfei Tu and Xingyun Chai

Journal of Ethnopharmacology, 2017, 207, 174
DOI: 10.1016/j.jep.2017.06.020

Bioactive Alkaloids from Nepalese Corydalis chaerophylla D.C. Acting on the Regulation of PCSK9 and LDL‐R In Vitro

Binita Maharjan, Ilaria Rossi, Stefania Sut, Timila Shrestha, Lok Kumar Shrestha, Jonathan P. Hill, Katsuhiko Ariga, Veronica Benetazzo, Maria Pia Adorni, Bianca Papotti, Shyam Sharan Shrestha, Ram Lal Swagat Shrestha, Nicola Ferri and Stefano Dall'Acqua

Chemistry & Biodiversity, 2024, 21
DOI: 10.1002/cbdv.202401388

Thioalkynes in Ring Forming Reactions

Lifen Peng, Zhiwen Yuan, Zilong Tang, Chunling Zeng and Xinhua Xu

The Chemical Record, 2023, 23
DOI: 10.1002/tcr.202300242

Rhodium-Catalyzed Annulation of Primary Benzylamine with α-Diazo Ketone toward Isoquinoline

Haoke Chu, Peiran Xue, Jin-Tao Yu and Jiang Cheng

J. Org. Chem., 2016, 81, 8009
DOI: 10.1021/acs.joc.6b01378

Pharmaceutical salt of tetrahydroberberine with sulfamic acid prepared via CAHBs

Yu-nan Zhang, Yan-fei Zhang, Li-xin Liu, Da-jun Zhang, Zhe Wang, Yu Zhang, Yan-ru Feng, Li-li Wu, Lei Zhang, Ying-li Liu, Yun-jie Zhang, Dong-yu Zou, Liang Chang, Xin Su, Guang-dong Cheng and Xue-song Zhang

Journal of Molecular Structure, 2020, 1221, 128816
DOI: 10.1016/j.molstruc.2020.128816

Phenolic contents and biological activities of two endemic plants in Turkey

Tuba Acet, Cengiz Çorbacı and Kadriye Özcan

South African Journal of Botany, 2021, 143, 457
DOI: 10.1016/j.sajb.2021.09.028

Electrochemically Driven Chalcogenative Cyclization of 2-Alkynyl Aryl Oxime: Access to Functionalized Isoquinolines

Jiajun Hu, Bo Li, Feng Xiong, Yue Xu, Zheyu Li, Linghui Gu, Wenbo Ma and Ruhuai Mei

J. Org. Chem., 2025, 90, 2626
DOI: 10.1021/acs.joc.4c02655

Pattern Recognition of Alkaloids by Inhibiting the Catalytic Activity of Dopzymes for Dopamine

Jing Zhu, Qing Hong Zhang and Wen Wu Wang

Anal. Chem., 2024
DOI: 10.1021/acs.analchem.4c01920

Plant isoquinoline alkaloids: Advances in the chemistry and biology of berberine

Sneha Singh, Nandini Pathak, Eram Fatima and Arvind Singh Negi

European Journal of Medicinal Chemistry, 2021, 226, 113839
DOI: 10.1016/j.ejmech.2021.113839

Dehydrocorydaline Accounts the Majority of Anti‐Inflammatory Property of Corydalis Rhizoma in Cultured Macrophage

Xiangpeng Kong, Zhicong Chen, Yingjie Xia, Etta Y. L. Liu, Haiqin Ren, Cheng Wang, Winnie W. H. Hu, Tina T. X. Dong, Rongbiao Pi, Karl W. K. Tsim and Roberto K. N. Cuman

Evidence-Based Complementary and Alternative Medicine, 2020, 2020
DOI: 10.1155/2020/4181696

The Use of Spectroscopic Methods for Structural Elucidation of Individual Secondary Metabolites Isolated from the Aerial Parts of Corydalis bracteata

V. I. Toporkova, A. O. Ponkratova, A. K. Whaley, V. G. Luzhanin and M. U. Goncharov

Vedomosti Nauchnogo tsentra ekspertizy sredstv meditsinskogo primeneniya, 2022, 12, 56
DOI: 10.30895/1991-2919-2022-12-1-56-64

Plant-Derived Alkaloids: The Promising Disease-Modifying Agents for Inflammatory Bowel Disease

Jiao Peng, Ting-Ting Zheng, Xi Li, Yue Liang, Li-Jun Wang, Yong-Can Huang and Hai-Tao Xiao

Front. Pharmacol., 2019, 10
DOI: 10.3389/fphar.2019.00351

Advancing in vitro elicitation of berberine: techniques and trends (2014–2024)

Arpita Kusha and Rajasekaran Chandrasekaran

Plant Cell Tiss Organ Cult, 2025, 162
DOI: 10.1007/s11240-025-03094-3

Enantioselective Syntheses of Strychnos and Chelidonium Alkaloids through Regio‐ and Stereocontrolled Cooperative Catalysis

Luke S. Hutchings‐Goetz, Chao Yang, James W. B. Fyfe and Thomas N. Snaddon

Angewandte Chemie, 2020, 132, 17709
DOI: 10.1002/ange.202005151

Synthesis of C3/C1-Substituted Tetrahydroisoquinolines

Mohamed Mihoubi, Nicola Micale, Angela Scala, Raoudha Jarraya, Amira Bouaziz, Tanja Schirmeister, Francesco Risitano, Anna Piperno and Giovanni Grassi

Molecules, 2015, 20, 14902
DOI: 10.3390/molecules200814902

Design and Synthesis of Cryptostyline I Derivatives: Cytotoxic Activity and Molecular Docking Insights

Sherzod N. Zhurakulov, Nilufar Z. Mamadalieva, Valentina I. Vinogradova, Adriano Mollica, Eleonora Procino, Kambarali K. Turgunov, Mukaddas R. Umarova, Ekaterina O. Terenteva and Shakhnoz S. Azimova

ChemistrySelect, 2025, 10
DOI: 10.1002/slct.202501526

Diet and Host Genetics Drive the Bacterial and Fungal Intestinal Metatranscriptome of Gilthead Sea Bream

Fernando Naya-Català, M. Carla Piazzon, Josep A. Calduch-Giner, Ariadna Sitjà-Bobadilla and Jaume Pérez-Sánchez

Front. Microbiol., 2022, 13
DOI: 10.3389/fmicb.2022.883738

Neuroprotective mechanism of corydaline in glutamate-induced neurotoxicity in HT22 cells

Baskar Selvaraj, Dae Won Kim, Ki-Yeon Yoo, Keunwan Park, Thi Thu Thuy Tran, Jae Wook Lee and Heesu Lee

Intern. J. Oral Biol., 2024, 49, 10
DOI: 10.11620/IJOB.2024.49.1.10

Tetrahydroberberine pharmaceutical salts/cocrystals with dicarboxylic acids: Charge-assisted hydrogen bond recognitions and solubility regulation

Yu-nan Zhang, Ying-li Liu, Li-xin Liu, Yan-ru Feng, Da-jun Zhang, Li-li Wu, Lei Zhang, Yun-jie Zhang, Dong-yu Zou, Liang Chang and Xin Su

Journal of Molecular Structure, 2019, 1197, 377
DOI: 10.1016/j.molstruc.2019.07.075

Gut microbiome composition and diversity of wild-caught and hatchery-bred milkfish (Chanos chanos) fry

Gardel Xyza L. Silvederio, Therese F. Javellana, Ande Bryle N. Genciana, Maria Alexandra G. Fontanilla, Rex Ferdinand M. Traifalgar, Fredson H. Huervana and Carmelo S. del Castillo

Journal of Genetic Engineering and Biotechnology, 2025, 23, 100520
DOI: 10.1016/j.jgeb.2025.100520

Antinociceptive effects of dehydrocorydaline in mouse models of inflammatory pain involve the opioid receptor and inflammatory cytokines

Zhi-Yu Yin, Lu Li, Shuai-Shuai Chu, Qing Sun, Zheng-Liang Ma and Xiao-Ping Gu

Sci Rep, 2016, 6
DOI: 10.1038/srep27129

Transcriptome analysis of 20 taxonomically related benzylisoquinoline alkaloid-producing plants

Jillian M. Hagel, Jeremy S. Morris, Eun-Jeong Lee, Isabel Desgagné-Penix, Crystal D. Bross, Limei Chang, Xue Chen, Scott C. Farrow, Ye Zhang, Jung Soh, Christoph W. Sensen and Peter J. Facchini

BMC Plant Biol, 2015, 15
DOI: 10.1186/s12870-015-0596-0

Recent advances in the synthesis of benzimidazolo[2,1-a]isoquinoline-6(5H)-one derivatives from N-methylacryloyl-2-arylbenzimidazoles

Qing-Gang Mei and Qing-Han Li

Tetrahedron, 2024, 160, 134050
DOI: 10.1016/j.tet.2024.134050

Two new isoquinoline alkaloids from the seeds of Nandina domestica

Juan Qin, Sheng-Yuan Zhang, Yu-Bo Zhang, Li-Feng Chen, Neng-Hua Chen, Zhong-Nan Wu, Ding Luo, Guo-Cai Wang and Yao-Lan Li

Natural Product Research, 2021, 35, 3254
DOI: 10.1080/14786419.2019.1696334

A medicinal plant compound, capnoidine, prevents the onset of inflammation in a mouse model of colitis

Catherine Shepherd, Paul Giacomin, Severine Navarro, Catherine Miller, Alex Loukas and Phurpa Wangchuk

Journal of Ethnopharmacology, 2018, 211, 17
DOI: 10.1016/j.jep.2017.09.024

Analyses of Total Alkaloid Extract ofCorydalis yanhusuoby Comprehensive RP × RP Liquid Chromatography with pH Difference

Xiaodong Wei, Hongling Shen, Lijun Wang, Qingyan Meng and Wenjie Liu

Journal of Analytical Methods in Chemistry, 2016, 2016, 1
DOI: 10.1155/2016/9752735

Isoquinolines from national herb Corydalis tomentella and neuroprotective effect against lipopolysaccharide-induced BV2 microglia cells

Yu-Meng Wang, Wen-Zhuo Ming, Hui Liang, Ying-Jiao Wang, Yun-Hong Zhang and Da-Li Meng

Bioorganic Chemistry, 2020, 95, 103489
DOI: 10.1016/j.bioorg.2019.103489

Intramolecular [2 + 2] Cycloaddition of Isocarbostyrils Catalyzed by an Iridium Visible-Light Photocatalyst

Noriyoshi Arai

J. Org. Chem., 2023, 88, 4848
DOI: 10.1021/acs.joc.3c00059

Asymmetric Synthesis of Tetrahydroisoquinoline Derivatives through 1,3-Dipolar Cycloaddition of C,N-Cyclic Azomethine Imines with Allyl Alkyl Ketones

Guipeng Feng, Guoyang Ma, Wenyan Chen, Shaohong Xu, Kaikai Wang and Shaoyan Wang

Molecules, 2021, 26, 2969
DOI: 10.3390/molecules26102969

DPD-Inspired Discovery of Novel LsrK Kinase Inhibitors: An Opportunity To Fight Antimicrobial Resistance

Silvia Stotani, Viviana Gatta, Prasanthi Medarametla, Mohan Padmanaban, Anna Karawajczyk, Fabrizio Giordanetto, Päivi Tammela, Tuomo Laitinen, Antti Poso, Dimitros Tzalis and Simona Collina

J. Med. Chem., 2019, 62, 2720
DOI: 10.1021/acs.jmedchem.9b00025

Dereplication of antioxidant compounds in Bene ( Pistacia atlantica subsp. mutica ) hull using a multiplex approach of HPLC–DAD, LC–MS and 1 H NMR techniques

Mitra Rezaie, Reza Farhoosh, Ngoc Pham, Ronald J. Quinn and Mehrdad Iranshahi

Journal of Pharmaceutical and Biomedical Analysis, 2016, 117, 352
DOI: 10.1016/j.jpba.2015.09.005

Simultaneous determination and pharmacokinetics of five alkaloids in rat plasma by ultra high performance liquid chromatography with tandem mass spectrometry after the oral administration of Corydalis bungeana Turcz extract

Lu Liu, Xueli Yu, Zhibin Wang, Jiahui Sun, Rong Pan, Chunjuan Yang and Lijun Wu

J of Separation Science, 2016, 39, 296
DOI: 10.1002/jssc.201500889

Screening of plants used in the European traditional medicine to treat memory disorders for acetylcholinesterase inhibitory activity and anti amyloidogenic activity

Eva S.B. Lobbens, Karina J. Vissing, Lene Jorgensen, Marco van de Weert and Anna K. Jäger

Journal of Ethnopharmacology, 2017, 200, 66
DOI: 10.1016/j.jep.2017.02.020

Development of Pd(OAc)2-catalyzed tandem oxidation of C N, C C, and C(sp3)–H bonds: Concise synthesis of 1-aroylisoquinoline, oxoaporphine, and 8-oxyprotoberberine alkaloids

Saeko Nishimoto, Hiromichi Nakahashi and Masahiro Toyota

Tetrahedron Letters, 2020, 61, 152599
DOI: 10.1016/j.tetlet.2020.152599

Total Synthesis of (±)-Impatien A via Aza-Heck Cyclization

Katerina M. Korch and Donald A. Watson

Org. Lett., 2021, 23, 7285
DOI: 10.1021/acs.orglett.1c02767

Cholinesterase inhibitors assessment of aporphine alkaloids from Annona crassiflora and molecular docking studies

Marília Fontes Barbosa, Allisson Benatti Justino, Mário Machado Martins, Kátia Roberta Anacleto Belaz, Francis Barbosa Ferreira, Ronaldo Junio de Oliveira, Amanda Danuello, Foued Salmen Espindola and Marcos Pivatto

Bioorganic Chemistry, 2022, 120, 105593
DOI: 10.1016/j.bioorg.2021.105593

Copper(II) Complexes with 1-(Isoquinolin-3-yl)heteroalkyl-2-ones: Synthesis, Structure and Evaluation of Anticancer, Antimicrobial and Antioxidant Potential

Łukasz Balewski, Tomasz Plech, Izabela Korona-Głowniak, Anna Hering, Małgorzata Szczesio, Andrzej Olczak, Patrick J. Bednarski, Jakub Kokoszka and Anita Kornicka

IJMS, 2023, 25, 8
DOI: 10.3390/ijms25010008

Ruthenium‐Catalyzed Oxidative Coupling of Primary Amines with Internal Alkynes through CH Bond Activation: Scope and Mechanistic Studies

Sara Ruiz, Pedro Villuendas, Manuel A. Ortuño, Agustí Lledós and Esteban P. Urriolabeitia

Chemistry A European J, 2015, 21, 8626
DOI: 10.1002/chem.201500338

The Phytochemical Scoulerine Inhibits Aurora Kinase Activity to Induce Mitotic and Cytokinetic Defects

Jinhua Li, Ziqi Yan, Hongmei Li, Qiong Shi, Vidhula Ahire, Shenqiu Zhang, Naganna Nimishetti, Dun Yang, Thaddeus D. Allen and Jing Zhang

J. Nat. Prod., 2021, 84, 2312
DOI: 10.1021/acs.jnatprod.1c00429

Metabolomic and Pharmacologic Insights of Aerial and Underground Parts of Glycyrrhiza uralensis Fisch. ex DC. for Maximum Utilization of Medicinal Resources

Liang Jiang, Waheed Akram, Biaobiao Luo, Sheng Hu, Mohammad Omar Faruque, Shakeel Ahmad, Nasim Ahmad Yasin, Waheed Ullah Khan, Aqeel Ahmad, Alexander N. Shikov, Jian Chen and Xuebo Hu

Front. Pharmacol., 2021, 12
DOI: 10.3389/fphar.2021.658670

Structures, biomimetic synthesis, and anti-SARS-CoV-2 activity of two pairs of enantiomeric phenylpropanoid-conjugated protoberberine alkaloids from the rhizomes of Corydalis decumbens

Jing-Guang Lu, Yingwei Wang, Ming-Rong Yang, Cai-Yun Wang, Jieru Meng, Jiazheng Liu, Zifeng Yang, Kongsong Wu, Li-Ping Bai, Guo-Yuan Zhu and Zhi-Hong Jiang

Arch. Pharm. Res., 2022, 45, 631
DOI: 10.1007/s12272-022-01401-6

DFT study on the Stereoselectivity of Asymmetric Synthesis of C, N‐Cyclic Azomethine Imines with Allyl Alkyl Ketones

Guipeng Feng, Jie Meng, Shaohong Xu, Shujing Wang and Xubin Yao

ChemistrySelect, 2024, 9
DOI: 10.1002/slct.202400150

Rupestrines A-D, alkaloids from the aerial parts of Corydalis rupestris

Maryam Naseri, Seyyed Ahmad Emami, Javad Asili, Zahra Tayarani-Najaran, Gholamreza Dehghan, Bernd Schneider and Mehrdad Iranshahi

Bioorganic Chemistry, 2018, 77, 651
DOI: 10.1016/j.bioorg.2018.02.019

Catalyst-free regio- and chemoselective addition of secondary phosphine oxides to isoquinolines

P. A. Volkov, N. K. Gusarova, A. A. Telezhkin, K. O. Khrapova, N. I. Ivanova, A. I. Albanov, T. I. Vakul’skaya, S. S. Khutsishvili and B. A. Trofimov

Russ Chem Bull, 2020, 69, 1102
DOI: 10.1007/s11172-020-2874-8

ChemInform Abstract: Biologically Active Isoquinoline Alkaloids with Drug‐Like Properties from the Genus Corydalis

M. Iranshahy, R. J. Quinn and M. Iranshahi

ChemInform, 2014, 45
DOI: 10.1002/chin.201435252

Metal-free intermolecular formal cycloadditions enable an orthogonal access to nitrogen heterocycles

Lan-Gui Xie, Supaporn Niyomchon, Antonio J. Mota, Leticia González and Nuno Maulide

Nat Commun, 2016, 7
DOI: 10.1038/ncomms10914

Isoquinoline alkaloids as prolyl oligopeptidase inhibitors

Lucie Cahlíková, Lucie Hulová, Martina Hrabinová, Jakub Chlebek, Anna Hošťálková, Markéta Adamcová, Marcela Šafratová, Daniel Jun, Lubomír Opletal, Miroslav Ločárek and Kateřina Macáková

Fitoterapia, 2015, 103, 192
DOI: 10.1016/j.fitote.2015.04.004

A simple and efficient metal free, additive, or base free dehydrogenation of tetrahydroisoquinolines using oxygen as a clean oxidant

Shanmugam Ramu and Baburaj Baskar

Can. J. Chem., 2021, 99, 311
DOI: 10.1139/cjc-2020-0295

Three Sequential C–N Bond Formations: tert-Butyl Nitrite as a N1 Synthon in a Three Component Reaction Leading to Imidazo[1,2-a]quinolines and Imidazo[2,1-a]isoquinolines

Prasenjit Sau, Amitava Rakshit, Anju Modi, Ahalya Behera and Bhisma K. Patel

J. Org. Chem., 2018, 83, 1056
DOI: 10.1021/acs.joc.7b02815

Enantioselective Syntheses of Strychnos and Chelidonium Alkaloids through Regio‐ and Stereocontrolled Cooperative Catalysis

Luke S. Hutchings‐Goetz, Chao Yang, James W. B. Fyfe and Thomas N. Snaddon

Angew Chem Int Ed, 2020, 59, 17556
DOI: 10.1002/anie.202005151

Therapeutic Potential of Benzimidazoisoquinoline Derivatives in Alleviating Murine Hepatic Fibrosis

Sowmya Mekala, Genji Sukumar, Shilpa Chawla, Ramasatyaveni Geesala, Jupally Prashanth, B. Jagan Mohan Reddy, Prathama Mainkar and Amitava Das

Chemistry & Biodiversity, 2024, 21
DOI: 10.1002/cbdv.202301429

Harnessing the chemical composition and anti-oxidant, anti-enzymatic, and anti-cancer activities of two Corydalis species (C. erdelii and C. solida) by using in vitro and in silico analysis

Tugce Duran, Gregorio Peron, Mirella Zancato, Gokhan Zengin, Mehmet Veysi Cetiz, Abdelhakim Bouyahya, Shakel Ahmed, Evren Yildiztugay, Stefano Dall’Acqua, Aleksandra Cvetanović Kljakić and Carlos L. Cespedes-Acuña

Food Bioscience, 2024, 61, 104762
DOI: 10.1016/j.fbio.2024.104762

Fluorescence Properties of a Novel Isoquinoline Derivative Tested in an Invertebrate Chordate, Ciona intestinalis

Silvia Mercurio, Lisa Moni, Giorgio Scarì, Raoul Manenti, Renata Riva and Roberta Pennati

ChemBioChem, 2021, 22, 2140
DOI: 10.1002/cbic.202100058

Bracteatinine and isogroenlandicine, two new isoquinoline alkaloids isolated from Corydalis bracteata and their effect on platelet function

Anastasiia O. Whaley, Andrei K. Whaley, Valeria Toporkova, Ekaterina Fock, Natalia Rukoyatkina, Sergey N. Smirnov, Gayrat B. Satimov, Baxtiyar A. Abduraxmanov and Stepan Gambaryan

Fitoterapia, 2023, 171, 105697
DOI: 10.1016/j.fitote.2023.105697

Actividad larvicida de extractos y fracciones proteicas de Annona muricata L. en Culex quinquefasciatus (Diptera: Culicidae)

Magaly Alejandra Brousett-Minaya, Juan Reyes-Larico, Edgar Chaparro and Miguel Bobadilla Álvarez

Rev. Acad. Colomb. Cienc. Ex. Fis. Nat., 2024, 48, 623
DOI: 10.18257/raccefyn.2649

A bird's eye view on a therapeutically ‘wonder molecule’: Berberine

Parth Patel

Phytomedicine Plus, 2021, 1, 100070
DOI: 10.1016/j.phyplu.2021.100070

First Report of Alternate Hosts of Willow Rust Disease Caused by Melampsora ferrinii in China

Zi-jia Peng, Chao-wei Xiong, Ze-yu Luo, Xiang-yun Hu, Zhong-dong Yu, Tian-xiang Chen, Yong Xu and Bin Wang

Plant Disease, 2022, 106, 324
DOI: 10.1094/PDIS-05-21-0958-PDN

Assembly of Pyran-Fused Isoquinolines via Rhodium-Catalyzed Double Annulations of Methyl Benzimidates with Diazo Compounds

Yinsong Wu, Enshen Zhang, Jiahui Duan, Keke Xu, Xinwei He and Yongjia Shang

Synthesis, 2022, 54, 4583
DOI: 10.1055/a-1844-5837

Copper-Catalyzed Benign and Efficient Oxidation of Tetrahydroisoquinolines and Dihydroisoquinolines Using Air as a Clean Oxidant

Bo Zheng, Tien Ha Trieu, Feng-Lei Li, Xing-Liang Zhu, Yun-Gang He, Qi-Qi Fan and Xiao-Xin Shi

ACS Omega, 2018, 3, 8243
DOI: 10.1021/acsomega.8b00855

Rh-Catalyzed Enantioselective Desymmetric Hydrogenation of α-Acetamido-1,3-indanediones Using Ether-Bridged Biphenyl Diphosphine Ligands

Yunnan Xu, Yicong Luo, Jianxun Ye, Delong Liu and Wanbin Zhang

J. Am. Chem. Soc., 2023, 145, 21176
DOI: 10.1021/jacs.3c07509

Copper-catalyzed radical cascade cyclization: Synthesis of benzylated benzimidazo [2,1-a]isoquinoline-6(5H)-ones

Zhenhua Li, Yingyan Cao, Lijun Chen, Dayou Rong, Guoqing Huang and Yuanyuan Xie

Tetrahedron, 2022, 122, 132952
DOI: 10.1016/j.tet.2022.132952

Introduction of Diverse Functional Groups to Isoquinolines by Microwave‐assisted Transition Metal‐catalyzed Coupling Reactions

A. Reum Park and Eul Kgun Yum

Bulletin Korean Chem Soc, 2018, 39, 1259
DOI: 10.1002/bkcs.11585

Corydalis cashmeriana var. longicalcarata (Papaveraceae), an addition to the flora of Western Himalaya, India

Tajamul Islam, Anzar Ahmad Khuroo, Sameer A. Sofi, Shabir A. Zargar, Aijaz Hassan Ganie and Irshad A. Nawchoo

Discov. Plants, 2025, 2
DOI: 10.1007/s44372-025-00260-x

Annulation of 1-methylisoquinoline with ethyl esters of 1-aryl-2-oxalylacetylenes: synthesis of functionalized oxazinoisoquinolines

K. V. Belyaeva, L. P. Nikitina, V. S. Gen’, A. V. Afonin and B. A. Trofimov

Russ Chem Bull, 2023, 72, 2687
DOI: 10.1007/s11172-023-4073-x

The Absolute Configuration and Cytotoxic Properties of Roehybridine β-N-oxide

Samad Nejad Ebrahimi, Zahra Bagheri-Zomorrodi, Abolfazl Shakeri, Milad Iranshahy, Milena Masullo, Sonia Piacente and Mehrdad Iranshahi

Natural Product Communications, 2016, 11
DOI: 10.1177/1934578X1601101210

Organic Cation Transporter 1 and 3 Contribute to the High Accumulation of Dehydrocorydaline in the Heart

Yingchun Chen, Cui Li, Yaodong Yi, Weijuan Du, Huidi Jiang, Su Zeng and Hui Zhou

Drug Metabolism and Disposition, 2020, 48, 1074
DOI: 10.1124/dmd.120.000025

Role of the Benzodioxole Group in the Interactions between the Natural Alkaloids Chelerythrine and Coptisine and the Human Telomeric G-Quadruplex DNA. A Multiapproach Investigation

F. Papi, M. Ferraroni, R. Rigo, S. Da Ros, C. Bazzicalupi, C. Sissi and P. Gratteri

J. Nat. Prod., 2017, 80, 3128
DOI: 10.1021/acs.jnatprod.7b00350

Metabolome analysis of 20 taxonomically related benzylisoquinoline alkaloid-producing plants

Jillian M. Hagel, Rupasri Mandal, Beomsoo Han, Jun Han, Donald R. Dinsmore, Christoph H. Borchers, David S. Wishart and Peter J. Facchini

BMC Plant Biol, 2015, 15
DOI: 10.1186/s12870-015-0594-2

Synthesis and Biological Activity of Aminoisoquinoline Schiff Bases

Runlai Li, Zhenming Zhang, He Li, Jiangyu Ji, Chi Liu, Change Dong, Yapeng Zhang and Jinghan Hong

HETEROCYCLES, 2023, 106, 174
DOI: 10.3987/COM-22-14776

Naturally Available Nitrogen-Containing Fused Heterocyclics as Prospective Lead Molecules in Medicinal Chemistry

Nivedita Bhardwaj, Akashdeep Pathania and Pradeep Kumar

CTM, 2021, 7, 5
DOI: 10.2174/2215083805666190613125700

Synthesis, Spectral Characterization, and Biological Evaluation of Novel [1,2,4]Triazolo[3,4‐a]isoquinolines and 5,6‐Dihydropyrrolo[2,1‐a]isoquinolines: Insights From Molecular Docking, ADMET, and Antibacterial Studies

Yara N. Laboud, Mohamed A. Mohamed Teleb, Doaa Zahran, Hamdi M. Hassaneen and Fatma M. Saleh

Chemistry & Biodiversity, 2025
DOI: 10.1002/cbdv.202500703