Issue 31, 2011
From the journal:

Chemical Communications

New insight on 2-naphthylmethyl (NAP) ether as a protecting group in carbohydrate synthesis: a divergent approach towards a high-mannose type oligosaccharide library†‡

Yao Li,a   Bimalendu Roya  and  Xinyu Liu*a  

* Corresponding authors

a Department of Chemistry, University of Pittsburgh, 219 Parkman Avenue, Pittsburgh, USA
E-mail: xinyuliu@pitt.edu
Fax: +1-412-624-8611
Tel: +1-412-624-6932

Abstract

A new method for selective cleavage of 2-naphthylmethyl (NAP) ether utilizing 10–20 molar excess of HF/pyridine in toluene was revealed and strategically applied to a divergent approach towards generation of a high-mannose type oligosaccharide library.

Graphical abstract: New insight on 2-naphthylmethyl (NAP) ether as a protecting group in carbohydrate synthesis: a divergent approach towards a high-mannose type oligosaccharide library

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Article information

DOI
https://doi.org/10.1039/C1CC13264D
Article type
Communication
Submitted
02 kesä 2011
Accepted
22 kesä 2011
First published
07 heinä 2011

Chem. Commun., 2011,47, 8952-8954

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New insight on 2-naphthylmethyl (NAP) ether as a protecting group in carbohydrate synthesis: a divergent approach towards a high-mannose type oligosaccharide library

Y. Li, B. Roy and X. Liu, Chem. Commun., 2011, 47, 8952 DOI: 10.1039/C1CC13264D

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