Issue 25, 2011
From the journal:

Chemical Communications

A rigid lanthanide binding tag for NMR structural analysis of carbohydrates†‡

Alvaro Mallagaray,a   Angeles Canales,b   Gema Domínguez,a   Jesús Jiménez-Barbero*c  and  Javier Pérez-Castells*a  

* Corresponding authors

a Facultad de Farmacia, Dpto. Química, Universidad San Pablo CEU, Urb. Montepríncipe, ctra. Boadilla km 5,300 Boadilla del Monte, 28668 Madrid, Spain
E-mail: jpercas@ceu.es

b Dpto. Química Organica I, Facultad de Ciencias Quimícas, Universidad Complutense de Madrid, Avd. Complutense s/n, Madrid, Spain

c Departamento de Biología Físico-Química, Centro de Investigaciones Biológicas, CSIC E-28040 Madrid, Spain
E-mail: jjbarbero@cib.csic.es

Abstract

The first synthesis of a carbohydrate molecule covalently bound to a rigid lanthanide binding tag is reported. This derivative has been designed as a new tool to provide long-range restraints for structural elucidation and molecular recognition studies of carbohydrates, thus extending the methodology already developed for proteins.

Graphical abstract: A rigid lanthanide binding tag for NMR structural analysis of carbohydrates

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Article information

DOI
https://doi.org/10.1039/C1CC11860A
Article type
Communication
Submitted
01 huhti 2011
Accepted
28 huhti 2011
First published
23 touko 2011

Chem. Commun., 2011,47, 7179-7181

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A rigid lanthanide binding tag for NMR structural analysis of carbohydrates

A. Mallagaray, A. Canales, G. Domínguez, J. Jiménez-Barbero and J. Pérez-Castells, Chem. Commun., 2011, 47, 7179 DOI: 10.1039/C1CC11860A

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