Peroxynitrite chemistry derived from nitric oxide reaction with a Cu(ii)–OOH species and a copper mediated NO reductive coupling reaction

Abstract

New peroxynitrite–copper chemistry ensues via addition of nitric oxide (˙NO_(g)) to a Cu^II–hydroperoxo species. In characterizing the system, the ligand–Cu(I) complex was shown to effect a seldom observed ˙NO_(g) reductive coupling reaction. Biological implications are discussed.