Issue 42, 2013

A Pt(ii)–Dip complex stabilizes parallel c-myc G-quadruplex

Abstract

A new G-quadruplex (GQ) stabilizer, [Pt(Dip)2](PF6)2 (Dip: 4,7-diphenyl-1,10-phenanthroline), is prepared by the microwave irradiation method. The complex can highly stabilize G-quadruplex, but has negligible interactions with duplex DNA. Aromatic anchors on the polypyridyl ligands bestow the stabilizer with a high binding preference towards parallel GQ.

Graphical abstract: A Pt(ii)–Dip complex stabilizes parallel c-myc G-quadruplex

Supplementary files

Article information

Article type
Communication
Submitted
01 helmi 2013
Accepted
02 huhti 2013
First published
03 huhti 2013

Chem. Commun., 2013,49, 4758-4760

A Pt(II)–Dip complex stabilizes parallel c-myc G-quadruplex

J. Wang, K. Lu, S. Xuan, Z. Toh, D. Zhang and F. Shao, Chem. Commun., 2013, 49, 4758 DOI: 10.1039/C3CC40868J

To request permission to reproduce material from this article, please go to the Copyright Clearance Center request page.

If you are an author contributing to an RSC publication, you do not need to request permission provided correct acknowledgement is given.

If you are the author of this article, you do not need to request permission to reproduce figures and diagrams provided correct acknowledgement is given. If you want to reproduce the whole article in a third-party publication (excluding your thesis/dissertation for which permission is not required) please go to the Copyright Clearance Center request page.

Read more about how to correctly acknowledge RSC content.

Social activity

Spotlight

Advertisements