Issue 16, 2024

Biomaterials as a new option for treating sensorineural hearing loss

Abstract

Sensorineural hearing loss (SNHL) usually involves damage to complex auditory pathways such as inner ear cells and auditory nerves. The highly intricate and nuanced characteristics of these cells render their repair and regeneration extremely challenging, making it difficult to restore hearing to normal levels once it has been compromised. The effectiveness of traditional drugs is so minimal that they provide little help with the treatment. Fortunately, extensive experiments have demonstrated that combining biomaterials with conventional techniques significantly enhances drug effectiveness. This article reviews the research progress of biomaterials in protecting hair cells and the auditory nerve, repairing genes related to hearing, and developing artificial cochlear materials. By organizing the knowledge presented in this article, perhaps new insights can be provided for the clinical management of SNHL.

Graphical abstract: Biomaterials as a new option for treating sensorineural hearing loss

Article information

Article type
Review Article
Submitted
28 فروردین 1403
Accepted
10 تیر 1403
First published
15 تیر 1403

Biomater. Sci., 2024,12, 4006-4023

Biomaterials as a new option for treating sensorineural hearing loss

L. Wang, R. Zhang, L. Jiang, S. Gao, J. Wu and Y. Jiao, Biomater. Sci., 2024, 12, 4006 DOI: 10.1039/D4BM00518J

To request permission to reproduce material from this article, please go to the Copyright Clearance Center request page.

If you are an author contributing to an RSC publication, you do not need to request permission provided correct acknowledgement is given.

If you are the author of this article, you do not need to request permission to reproduce figures and diagrams provided correct acknowledgement is given. If you want to reproduce the whole article in a third-party publication (excluding your thesis/dissertation for which permission is not required) please go to the Copyright Clearance Center request page.

Read more about how to correctly acknowledge RSC content.

Social activity

Spotlight

Advertisements