Issue 22, 2023

Commercial and novel anticoagulant ECMO coatings: a review

Abstract

Extracorporeal membrane oxygenation (ECMO) is an invasive and last-resort treatment for circulatory and respiratory failure. Prolonged ECMO support can disrupt the coagulation and anticoagulation systems in a patient, leading to adverse consequences, such as bleeding and thrombosis. To address this problem, anticoagulation coatings have been developed for use in ECMO circuits. This article reviews commonly used commercial and novel anticoagulant coatings developed in recent years and proposes a new classification of coatings based on the current state. While commercial coatings have been used clinically for decades, this review focuses on comparing the effectiveness and stability of coatings to support clinical selections. Furthermore, novel anticoagulation coatings often involve complex mechanisms and elaborate design strategies, and this review summarises representative studies on mainstream anticoagulation coatings to provide a point of reference for future studies.

Graphical abstract: Commercial and novel anticoagulant ECMO coatings: a review

Article information

Article type
Review Article
Submitted
14 اسفند 1401
Accepted
18 اردیبهشت 1402
First published
19 اردیبهشت 1402

J. Mater. Chem. B, 2023,11, 4832-4841

Commercial and novel anticoagulant ECMO coatings: a review

C. Zhao, K. Sheng, T. Bao, T. Shi, P. Liu, Y. Yan and X. Zheng, J. Mater. Chem. B, 2023, 11, 4832 DOI: 10.1039/D3TB00471F

To request permission to reproduce material from this article, please go to the Copyright Clearance Center request page.

If you are an author contributing to an RSC publication, you do not need to request permission provided correct acknowledgement is given.

If you are the author of this article, you do not need to request permission to reproduce figures and diagrams provided correct acknowledgement is given. If you want to reproduce the whole article in a third-party publication (excluding your thesis/dissertation for which permission is not required) please go to the Copyright Clearance Center request page.

Read more about how to correctly acknowledge RSC content.

Social activity

Spotlight

Advertisements