Issue 41, 2009
From the journal:

Chemical Communications

NeoPHOX—an easily accessible P,N-ligand for iridium-catalyzed asymmetric hydrogenation: preparation, scope and application in the synthesis of demethyl methoxycalamenene†

Marcus G. Schremsa  and  Andreas Pfaltz*a  

* Corresponding authors

a Department of Chemistry, University of Basel, St. Johanns-Ring 19, CH-4056 Basel, Switzerland
E-mail: andreas.pfaltz@unibas.ch
Fax: +41 61-267-1103

Abstract

Using a new class of chiral iridium hydrogenation catalysts, the antitumor natural product demethyl calamenene was synthesized in four steps in >20% overall yield and high enantiomeric purity.

Graphical abstract: NeoPHOX—an easily accessible P,N-ligand for iridium-catalyzed asymmetric hydrogenation: preparation, scope and application in the synthesis of demethyl methoxycalamenene

About
Cited by
Related
Download options Please wait...

Supplementary files

Article information

DOI
https://doi.org/10.1039/B912680E
Article type
Communication
Submitted
05 تیر 1388
Accepted
23 مرداد 1388
First published
05 شهریور 1388

Chem. Commun., 2009, 6210-6212

Permissions

Request permissions

NeoPHOX—an easily accessible P,N-ligand for iridium-catalyzed asymmetric hydrogenation: preparation, scope and application in the synthesis of demethyl methoxycalamenene

M. G. Schrems and A. Pfaltz, Chem. Commun., 2009, 6210 DOI: 10.1039/B912680E

To request permission to reproduce material from this article, please go to the Copyright Clearance Center request page.

If you are an author contributing to an RSC publication, you do not need to request permission provided correct acknowledgement is given.

If you are the author of this article, you do not need to request permission to reproduce figures and diagrams provided correct acknowledgement is given. If you want to reproduce the whole article in a third-party publication (excluding your thesis/dissertation for which permission is not required) please go to the Copyright Clearance Center request page.

Read more about how to correctly acknowledge RSC content.

Social activity

Spotlight

Advertisements