2,5-Diazabicyclo[2.2.1]heptane (2,5-DBH) is a conformationally rigid bicyclic diamine and a privileged scaffold in medicinal chemistry, enabling diverse synthetic modifications and broad therapeutic applications across multiple disease areas.
Herein, we report on the influence of size- and shape-dependent molecular affinity on the supramolecular self-assembly in the solid state of prism[n]arene-alkyl dibromide (n = 5, 6) systems.
A new container-less droplet merging method in combination with high-speed imaging and spectroscopy were employed to explore the chemistry in the initial stages of ignition in a hyperogolic ionic liquid – oxidizer reaction.
1,4-Thiazine frameworks bearing a halide X (X = I, Br or Cl) at the α-position of their sulfur atom were prepared in domino Morin-Rearrangement end/or Halogenation in one or two steps, followed by their arylation based on Suzuki-Miyaura coupling.
The PA-coordinated injectable hydrogel exhibits a high swelling ratio, stable adhesiveness, a low hemolysis rate, and good cytocompatibility, holding promising potential for rapid hemostasis of internal organs under minimally invasive conditions.