Three Stryker-type copper hydride nanoclusters ([CuH]6) were synthesized. Variations in the electron-donating properties of phosphine ligands affect the hydrogenation reaction and reduction process activity of [CuH]6.
A stable Cu(I)-carboxylate MOF is fabricated by ascorbic acid reduction, which breaks HSAB theory and achieves in situ phase transitions. The resultant Cu2H2DOBDC acting as a CuAAC catalyst exhibited superior catalytic performance.
A cryoEM structure of ammonia monooxygenase in native membranes reveals for the first time simultaneous occupancy of the active site CuC and CuD centers, facilitated by an endogenous lipid.
Noncovalent interactions override electronic effects on the regioselectivity of the SNAr step that cleaves a C–F bond of polyfluoroarenes in a CuH-catalyzed hydroarylation of alkenes.
This review summarizes key advances from 2018 to 2025 that demonstrate how selectivity in carbonylation can be effectively controlled not by the inherent reactivity of the substrate, but by the catalytic system itself.