In this review, we provide a brief yet comprehensive account of the metal-catalysed syntheses of four isomeric carbolines (α/β/γ/δ) along with the mechanistic pathways involved in the aforesaid strategies.
This review presents a detailed analysis of β-carbolines as promising multi-target antimalarial agents.
A highly efficient enantioselective direct C–H functionalization of β-carbolines via a Minisci-type radical process under a photo-redox and chiral phosphoric acid cooperative catalytic system has been disclosed.
β-Carbolines norharman and harman, belonging to the class of heterocyclic aromatic amines (HAAs), are typical hazardous substances produced during the thermal processing of food.
The first palladium-catalyzed cascade reaction combining Pd(II)-catalyzed nucleophilic cyclization of alkynes and intramolecular redox-relay Heck arylation of alkenols has been developed.