Aoife M. Kearney, Stuart G. Collins and Anita R. Maguire
React. Chem. Eng., 2024,9, 990-1013
From themed collection:
In Celebration of Klavs Jensen’s 70th Birthday
Abstract
This review highlights the advantages of incorporating Process Analytical Technologies into continuous flow processes, especially in the context of telescoped multistep flow sequences.
George Lyall-Brookes, Alex C. Padgham and Anna G. Slater
Digital Discovery, 2025,4, 2364-2400
Abstract
Combining high throughput experimentation with continuous flow techniques opens new opportunities across a range of chemical fields.
Ricardo Labes, Julio C. Pastre, Richard J. Ingham, Claudio Battilocchio, Henrique M. Marçon, Mariana C. F. C. B. Damião, Duc N. Tran and Steven V. Ley
React. Chem. Eng., 2024,9, 558-565
From themed collection:
In Celebration of Klavs Jensen’s 70th Birthday
Abstract
The synthesis of 2-pyrazolines from aldehydes via cycloaddition of unstabilised diazo species and alkenes is reported, including automated library generation and graphical interface for reaction control.
Stanisław Michałek, Anna M. Maj, Lidia Gurba-Bryśkiewicz, Wioleta Maruszak, Krzysztof Wiśniewski, Marcin Zagozda, Mariola Stypik, Krzysztof Dubiel and Maciej Wieczorek
RSC Adv., 2024,14, 28516-28523
Abstract
Development of a telescopic sequence for the last two steps in the CPL302415 synthesis (71.6% total yield). The procedure was generalized into the synthesis of other biologically active PI3Kδ inhibitors based on the pyrazolo[1,5-a]pyrimidine core.
Alireza Nazari Khodadadi, Ejdi Cela, Dario Marchionni, Fan Huang, Francesco Ferlin and Luigi Vaccaro
Green Chem., 2024,26, 7059-7066
From themed collection:
2024 Green Chemistry Hot Articles
Abstract
Green inspired synthesis of hexaaryl-substituted borazines.