In this study, we synthesized and characterized ten chromenopyrimidine derivatives using analytical and spectroscopic methods.
Highly active α-glucosidase inhibitors (up to 41 times more potent than acarbose) were synthesised, mimicking ganocochlearines, tetracyclic Ganoderma alkaloids.
A novel synthesis method has been developed for the construction of 2,4-diarylpyridines. The reaction includes reduction, Michael addition, decarboxylation, intramolecular cyclization, oxidation, ring-opening and aromatization reaction.
Mechanochemical activation can significantly enhance the reactivity of otherwise inert C–H bonds, enabling the unprecedented benzannulation of 2-methylbenzaldehyde and 2-methylindole-3-carbaldehyde with 3-formylchromones.
A brief summary of several kinds of heterocyclic rings (spiro, fused/bridged, and simple), which have been synthesized using significant approaches involving DBU as a catalyst, solvent, base, or reactant, is systematically provided.