Bacterial cell death to overcome drug resistance with multitargeting bis-naphthalimides as potent antibacterial agents against Enterococcus faecalis

Saurabh Gupta, Vijay Luxami and Kamaldeep Paul

J. Mater. Chem. B, 2024, 12, 5645
DOI: 10.1039/D3TB02804F

Aloe-emodin derived azoles as a new structural type of potential antibacterial agents: design, synthesis, and evaluation of the action on membrane, DNA, and MRSA DNA isomerase

Xin-Yuan Liang, Narsaiah Battini, Yan-Fei Sui, Mohammad Fawad Ansari, Lin-Ling Gan and Cheng-He Zhou

RSC Med. Chem., 2021, 12, 602
DOI: 10.1039/D0MD00429D

Harnessing the zinc(ii) bis-terpyridine complex to overcome drug resistance: mechanistic insights into antibacterial activity

Sourav Sutradhar, Saurabh Gupta, Parnashabari Sarkar, Dipankar Das, Kamaldeep Paul and Biswa Nath Ghosh

Mater. Adv., 2026, 7, 3627
DOI: 10.1039/D5MA00502G

A Potential Combination Therapy of Berberine Hydrochloride With Antibiotics Against Multidrug-Resistant Acinetobacter baumannii

Xiaobo Li, Yanqing Song, Lina Wang, Guangbo Kang, Ping Wang, Huabing Yin and He Huang

Front. Cell. Infect. Microbiol., 2021, 11
DOI: 10.3389/fcimb.2021.660431

Design and biological evaluation of a novel type of potential multi-targeting antimicrobial sulfanilamide hybrids in combination of pyrimidine and azoles

Yan-Fei Sui, Di Li, Juan Wang, Rammohan R. Yadav Bheemanaboina, Mohammad Fawad Ansari, Lin-Ling Gan and Cheng-He Zhou

Bioorganic & Medicinal Chemistry Letters, 2020, 30, 126982
DOI: 10.1016/j.bmcl.2020.126982

Exploring the binding mechanism of Ginsenoside Rd to Bovine Serum Albumin: Experimental studies and computational simulations

Jialiang Lin, Min Tang, Manjunath D. Meti, Yong Liu, Qingguo Han, Xu Xu, Yuan Zheng, Zhendan He, Zhangli Hu and Hong Xu

Journal of Dispersion Science and Technology, 2022, 43, 2037
DOI: 10.1080/01932691.2021.1915154

An unanticipated discovery of novel naphthalimidopropanediols as potential broad-spectrum antibacterial members

Peng-Li Zhang, Mouna Hind Laiche, Yan-Liang Li, Wei-Wei Gao, Jian-Mei Lin and Cheng-He Zhou

European Journal of Medicinal Chemistry, 2022, 241, 114657
DOI: 10.1016/j.ejmech.2022.114657

Identification of unique indolylcyanoethylenyl sulfonylanilines as novel structural scaffolds of potential antibacterial agents

Xue-Mei Zhou, Qian-Yue Li, Xing Lu, Rammohan R.Yadav Bheemanaboina, Bo Fang, Gui-Xin Cai and Cheng-He Zhou

European Journal of Medicinal Chemistry, 2023, 260, 115773
DOI: 10.1016/j.ejmech.2023.115773

Plant protoberberine alkaloids: structural diversity, biosynthesis, synthesis, biological activity, structure-activity relationships and clinical applications of berberine

Weiqi Jiang, Wen Zhang, Chenxin Jing, Han Zhou, Zhi-Jun Zhang, Rui Wang and Ying-Qian Liu

Phytochemistry, 2026, 242, 114690
DOI: 10.1016/j.phytochem.2025.114690

2‐Hydroxypropyl Group Linked Derivatives of Indole Azoles as Potential Multifunctional Antibacterial Candidates for Effectively Inhibiting the Activity of MRSA and Responding Inflammatory Factors

Yuanyuan Hu, Hao Zhou, Jinxu Huang, Guangxing Pan, Hao Wang, Tiansheng Wang, Congwei Yu, Ling Zhang, Deming Gou and Jiaheng Zhang

Chemistry An Asian Journal, 2023, 18
DOI: 10.1002/asia.202300054

Novel Schiff Base‐conjugated para‐Aminobenzenesulfonamide Indole Hybrids as Potentially Muti‐targeting Blockers against Staphylococcus aureus

Yuanyuan Hu, Ling Zhang, Jinxu Huang, Tiansheng Wang, Jichuan Zhang, Congwei Yu, Guangxing Pan, Ling Zhang, Zhenye Zhu and Jiaheng Zhang

Asian J Org Chem, 2022, 11
DOI: 10.1002/ajoc.202100737

Thiazolyl hydrazineylidenyl indolones as unique potential multitargeting broad-spectrum antimicrobial agents

Wen-Hao Zhao, Jia-He Xu, Vijai Kumar Reddy Tangadanchu and Cheng-He Zhou

European Journal of Medicinal Chemistry, 2023, 256, 115452
DOI: 10.1016/j.ejmech.2023.115452

Novel metronidazole-derived three-component hybrids as promising broad-spectrum agents to combat oppressive bacterial resistance

Fen-Fen Li, Peng-Li Zhang, Vijai Kumar Reddy Tangadanchu, Shuo Li and Cheng-He Zhou

Bioorganic Chemistry, 2022, 122, 105718
DOI: 10.1016/j.bioorg.2022.105718

Novel coumarin aminophosphonates as potential multitargeting antibacterial agents against Staphylococcus aureus

Xun-Cai Yang, Chun-Mei Zeng, Srinivasa Rao Avula, Xin-Mei Peng, Rong-Xia Geng and Cheng-He Zhou

European Journal of Medicinal Chemistry, 2023, 245, 114891
DOI: 10.1016/j.ejmech.2022.114891

Comprehensive Insights into Medicinal Research on Imidazole-Based Supramolecular Complexes

Shu-Rui Li, Yi-Min Tan, Ling Zhang and Cheng-He Zhou

Pharmaceutics, 2023, 15, 1348
DOI: 10.3390/pharmaceutics15051348

Coumarin thiazoles as unique structural skeleton of potential antimicrobial agents

Xun-Cai Yang, Chun-Fang Hu, Peng-Li Zhang, Shuo Li, Chun-Sheng Hu, Rong-Xia Geng and Cheng-He Zhou

Bioorganic Chemistry, 2022, 124, 105855
DOI: 10.1016/j.bioorg.2022.105855

A new exploration towards aminothiazolquinolone oximes as potentially multi-targeting antibacterial agents: Design, synthesis and evaluation acting on microbes, DNA, HSA and topoisomerase IV

Liang-Liang Wang, Narsaiah Battini, Rammohan R. Yadav Bheemanaboina, Mohammad Fawad Ansari, Jin-Ping Chen, Yun-Peng Xie, Gui-Xin Cai, Shao-Lin Zhang and Cheng-He Zhou

European Journal of Medicinal Chemistry, 2019, 179, 166
DOI: 10.1016/j.ejmech.2019.06.046

Discovery of unique thiazolidinone-conjugated coumarins as novel broad spectrum antibacterial agents

Xun-Cai Yang, Peng-Li Zhang, Kannekanti Vijaya Kumar, Shuo Li, Rong-Xia Geng and Cheng-He Zhou

European Journal of Medicinal Chemistry, 2022, 232, 114192
DOI: 10.1016/j.ejmech.2022.114192

New Efforts toward Aminothiazolylquinolones with Multitargeting Antibacterial Potential

Jing Zhang, Narsaiah Battini, Jia-Ming Ou, Shao-Lin Zhang, Ling Zhang and Cheng-He Zhou

J. Agric. Food Chem., 2023, 71, 2322
DOI: 10.1021/acs.jafc.2c08293

Natural Berberine-derived Azolyl Ethanols as New Structural Antibacterial Agents against Drug-Resistant Escherichia coli

Hang Sun, Shi-Yu Huang, Ponmani Jeyakkumar, Gui-Xin Cai, Bo Fang and Cheng-He Zhou

J. Med. Chem., 2022, 65, 436
DOI: 10.1021/acs.jmedchem.1c01592

Research progress on berberine and its derivatives

Jina Sun, Jinlin Wang, Xiong Xie, Jiang Wang, Yu Zhou and Hong Liu

Sci. Sin.-Chim, 2025, 55, 2331
DOI: 10.1360/SSC-2025-0104

Unlocking the Antibacterial Potential of Naphthalimide–Coumarins to Overcome Drug Resistance with Antibiofilm and Membrane Disruption Ability against Escherichia coli

Saurabh Gupta, Vijay Luxami and Kamaldeep Paul

ACS Appl. Mater. Interfaces, 2025, 17, 4380
DOI: 10.1021/acsami.4c13337

Indole-nitroimidazole conjugates as efficient manipulators to decrease the genes expression of methicillin-resistant Staphylococcus aureus

Zhen-Zhen Li, Vijai Kumar Reddy Tangadanchu, Narsaiah Battini, Rammohan R. Yadav Bheemanaboina, Zhong-Lin Zang, Shao-Lin Zhang and Cheng-He Zhou

European Journal of Medicinal Chemistry, 2019, 179, 723
DOI: 10.1016/j.ejmech.2019.06.093

Natural aloe emodin-hybridized sulfonamide aminophosphates as novel potential membrane-perturbing and DNA-intercalating agents against Enterococcus faecalis

Zhao Deng, Hang Sun, Rammohan R. Yadav Bheemanaboina, Yan Luo and Cheng-He Zhou

Bioorganic & Medicinal Chemistry Letters, 2022, 64, 128695
DOI: 10.1016/j.bmcl.2022.128695

An Unexpected Discovery Toward Novel Membrane Active Sulfonyl Thiazoles As Potential MRSA DNA Intercalators

Yuan-Yuan Hu, Juan Wang, Tie-Jun Li, Rammohan R Yadav Bheemanaboina, Mohammad Fawad Ansari, Yu Cheng and Cheng-He Zhou

Future Med. Chem., 2020, 12, 1709
DOI: 10.4155/fmc-2019-0303

Current development and structure–activity relationship study of berberine derivatives

Xiong-Fei Luo, Han Zhou, Peng Deng, Shao-Yong Zhang, Yi-Rong Wang, Yan-Yan Ding, Guang-Han Wang, Zhi-Jun Zhang, Zheng-Rong Wu and Ying-Qian Liu

Bioorganic & Medicinal Chemistry, 2024, 112, 117880
DOI: 10.1016/j.bmc.2024.117880

Unique Carbazole-Oxadiazole Derivatives as New Potential Antibiotics for Combating Gram-Positive and -Negative Bacteria

Yun-Peng Xie, Nagarajan Sangaraiah, Jiang-Ping Meng and Cheng-He Zhou

J. Med. Chem., 2022, 65, 6171
DOI: 10.1021/acs.jmedchem.2c00001

A New Discovery towards Novel Skeleton of Benzimidazole‐Conjugated Pyrimidinones as Unique Effective Antibacterial Agents

Xi Yang, Rasheed Syed, Bo Fang and Cheng‐He Zhou

Chin. J. Chem., 2022, 40, 2642
DOI: 10.1002/cjoc.202200326

Novel chalcone-conjugated, multi-flexible end-group coumarin thiazole hybrids as potential antibacterial repressors against methicillin-resistant Staphylococcus aureus

Yuanyuan Hu, Chunfang Hu, Guangxing Pan, Congwei Yu, Mohammad Fawad Ansari, Rammohan R. Yadav Bheemanaboina, Yu Cheng, Chenghe Zhou and Jiaheng Zhang

European Journal of Medicinal Chemistry, 2021, 222, 113628
DOI: 10.1016/j.ejmech.2021.113628

Research Progress in Chemical Synthesis and Biosynthesis of Bioactive Imidazole Alkaloids

Bing Liu, Jinhua Wu, Ting Zhu, Xue Tian, Ning Chen, Wenlan Li and Ting Li

MROC, 2025, 22, 427
DOI: 10.2174/0118756298313032240529094738

Unlocking the antibacterial potential of berberine–thioether derivatives against plant canker

Mei Zhu and Guiping Ouyang

Pest Management Science, 2026
DOI: 10.1002/ps.70715

Identification of Unique Quinazolone Thiazoles as Novel Structural Scaffolds for Potential Gram-Negative Bacterial Conquerors

Jie Wang, Mohammad Fawad Ansari and Cheng-He Zhou

J. Med. Chem., 2021, 64, 7630
DOI: 10.1021/acs.jmedchem.1c00334

Unique para-aminobenzenesulfonyl oxadiazoles as novel structural potential membrane active antibacterial agents towards drug-resistant methicillin resistant Staphylococcus aureus

Juan Wang, Mohammad Fawad Ansari and Cheng-He Zhou

Bioorganic & Medicinal Chemistry Letters, 2021, 41, 127995
DOI: 10.1016/j.bmcl.2021.127995

Synthesis and Biological Evaluation of Quinazolonethiazoles as New Potential Conquerors towards Pseudomonas Aeruginosa

Jie Wang, Narsaiah Battini, Mohammad Fawad Ansari and Cheng‐He Zhou

Chin. J. Chem., 2021, 39, 1093
DOI: 10.1002/cjoc.202000627

Novel berberine derivatives as adjuvants in the battle against Acinetobacter baumannii: A promising strategy for combating multi-drug resistance

Liping Zhao, Xixi Guo, Zhimeng Zhang, Xi Lu, Qingxuan Zeng, Tianyun Fan, Xintong Zhang, Fenbei Chen, Mengyi Xu, Min Yuan, Zhenjun Li, Jiandong Jiang, Jing Pang, Xuefu You, Yanxiang Wang and Danqing Song

Chinese Chemical Letters, 2024, 35, 109506
DOI: 10.1016/j.cclet.2024.109506

Discovery of novel phenylhydrazone-based oxindole-thiolazoles as potent antibacterial agents toward Pseudomonas aeruginosa

Fen-Fen Li, Wen-Hao Zhao, Vijai Kumar Reddy Tangadanchu, Jiang-Ping Meng and Cheng-He Zhou

European Journal of Medicinal Chemistry, 2022, 239, 114521
DOI: 10.1016/j.ejmech.2022.114521

Ethylenic conjugated coumarin thiazolidinediones as new efficient antimicrobial modulators against clinical methicillin-resistant Staphylococcus aureus

Chun-Fang Hu, Peng-Li Zhang, Yan-Fei Sui, Jing-Song Lv, Mohammad Fawad Ansari, Narsaiah Battini, Shuo Li, Cheng-He Zhou and Rong-Xia Geng

Bioorganic Chemistry, 2020, 94, 103434
DOI: 10.1016/j.bioorg.2019.103434

Identification of a Novel Antifungal Backbone of Naphthalimide Thiazoles with Synergistic Potential for Chemical and Dynamic Treatment

Peng-Li Zhang, Gopala Lavanya, Yang Yu, Bo Fang and Cheng-He Zhou

Future Med. Chem., 2021, 13, 2047
DOI: 10.4155/fmc-2021-0162

Investigation of ROS-mediated oxidative stress and membrane disruption caused by Cu(II)-isatin semicarbazone against S. aureus and A. calcoaceticus

Irtiqa Ashraf Mir, Iqubal Singh, Kamaldeep Paul, Saurabh Gupta, Ray J. Butcher, Rannan Carmieli and Rekha Sharma

Bioorganic Chemistry, 2026, 175, 109805
DOI: 10.1016/j.bioorg.2026.109805

Pyrimidinetrione‐imidazoles as a Unique Structural Type of Potential Agents towards Candida Albicans: Design, Synthesis and Biological Evaluation

Yan‐Fei Sui, Mohammad Fawad Ansari and Cheng‐He Zhou

Chemistry An Asian Journal, 2021, 16, 1417
DOI: 10.1002/asia.202100146

Dihydropyrimidinone imidazoles as unique structural antibacterial agents for drug-resistant gram-negative pathogens

Xi Yang, Hang Sun, Swetha Kameswari Maddili, Shuo Li, Ren-Guo Yang and Cheng-He Zhou

European Journal of Medicinal Chemistry, 2022, 232, 114188
DOI: 10.1016/j.ejmech.2022.114188

Novel aminothiazoximone-corbelled ethoxycarbonylpyrimidones with antibiofilm activity to conquer Gram-negative bacteria through potential multitargeting effects

Wei Li, Xi Yang, Nisar Ahmad, Shao-Lin Zhang and Cheng-He Zhou

European Journal of Medicinal Chemistry, 2024, 268, 116219
DOI: 10.1016/j.ejmech.2024.116219

Novel Schiff base-bridged multi-component sulfonamide imidazole hybrids as potentially highly selective DNA-targeting membrane active repressors against methicillin-resistant Staphylococcus aureus

Yuanyuan Hu, Guangxing Pan, Zhixiong Yang, Tiejun Li, Juan Wang, Mohammad Fawad Ansari, Chunfang Hu, Rammohan R. Yadav Bheemanaboina, Yu Cheng, Chenghe Zhou and Jiaheng Zhang

Bioorganic Chemistry, 2021, 107, 104575
DOI: 10.1016/j.bioorg.2020.104575

Potential antibacterial ethanol-bridged purine azole hybrids as dual-targeting inhibitors of MRSA

Yuanyuan Hu, Shunyou Hu, Guangxing Pan, Dong Wu, Tiansheng Wang, Congwei Yu, Mohammad Fawad Ansari, Rammohan R. Yadav Bheemanaboina, Yu Cheng, Ligang Bai, Chenghe Zhou and Jiaheng Zhang

Bioorganic Chemistry, 2021, 114, 105096
DOI: 10.1016/j.bioorg.2021.105096

An updated review of isoquinoline alkaloids: Biological activity and mode of action, structural modifications, and agricultural applications

Xiaorong Yang, Tong Bu, Yuchao Ma, Xiaoyan Yu, Zile Gong, Jing Wang, Xueyan Liu, Janar Jenis, Hongwei Hu, Xiaolou Miao and Xiaofei Shang

Industrial Crops and Products, 2025, 234, 121591
DOI: 10.1016/j.indcrop.2025.121591

Novel carbazole-oxadiazoles as potential Staphylococcus aureus germicides

Yun-Peng Xie, Mohammad Fawad Ansari, Shao-Lin Zhang and Cheng-He Zhou

Pesticide Biochemistry and Physiology, 2021, 175, 104849
DOI: 10.1016/j.pestbp.2021.104849

Discovery of novel purinylthiazolylethanone derivatives as anti-Candida albicans agents through possible multifaceted mechanisms

Yan-Fei Sui, Mohammad Fawad Ansari, Bo Fang, Shao-Lin Zhang and Cheng-He Zhou

European Journal of Medicinal Chemistry, 2021, 221, 113557
DOI: 10.1016/j.ejmech.2021.113557

An Efficient and Eco‐Friendly Synthesis of Protoberberine and 13‐Me Protoberberine Alkaloids via Electrochemical Acceptorless Dehydrogenation

Weijian Li, Shiqi Huang, Meifen Jiang, Yu Chen, Zhi Yang, Pei Tang and Fener Chen

ChemCatChem, 2023, 15
DOI: 10.1002/cctc.202201553

Acridinium‐conjugated aromatic heterocycles as highly potent FtsZ inhibitors: Design, synthesis, and biological evaluation

Di Song, Nan Zhang, Yangchun Ma, Shenyan Zhang, Weijin Chen, Ting Guo and Shutao Ma

Archiv der Pharmazie, 2022, 355
DOI: 10.1002/ardp.202100400

Natural product derived promising anti-MRSA drug leads: A review

Srikanth Gatadi, Jitendra Gour and Srinivas Nanduri

Bioorganic & Medicinal Chemistry, 2019, 27, 3760
DOI: 10.1016/j.bmc.2019.07.023

Developing Dual-State Emission Berberine Derivatives as Theranostic Agents by Reducing Nonradiative Transition Pathways

Fuquan Xie, Beibei Xu, Peng Chen, Yushan Qin, Wenbin Pei, Jiangquan Li, Tianhui Hu, Qi Gao, Siying Chen, Yandong Zhang, Defa Li and Zhongjian Xie

J. Med. Chem., 2025, 68, 11217
DOI: 10.1021/acs.jmedchem.5c00191

Benzenesulfonyl thiazoloimines as unique multitargeting antibacterial agents towards Enterococcus faecalis

Xue-Mei Zhou, Yuan-Yuan Hu, Bo Fang and Cheng-He Zhou

European Journal of Medicinal Chemistry, 2023, 248, 115088
DOI: 10.1016/j.ejmech.2023.115088

Design and Synthesis of Sulfanilamide Aminophosphonates as Novel Antibacterial Agents towards Escherichia coli

Juan Wang, Mohammad Fawad Ansari, Jian‐Mei Lin and Cheng‐He Zhou

Chin. J. Chem., 2021, 39, 2251
DOI: 10.1002/cjoc.202100165

An unanticipated discovery towards novel naphthalimide corbelled aminothiazoximes as potential anti-MRSA agents and allosteric modulators for PBP2a

Peng-Li Zhang, Lavanya Gopala, Shao-Lin Zhang, Gui-Xin Cai and Cheng-He Zhou

European Journal of Medicinal Chemistry, 2022, 229, 114050
DOI: 10.1016/j.ejmech.2021.114050

Membrane active 7-thiazoxime quinolones as novel DNA binding agents to decrease the genes expression and exert potent anti-methicillin-resistant Staphylococcus aureus activity

Jin-Ping Chen, Narsaiah Battini, Mohammad Fawad Ansari and Cheng-He Zhou

European Journal of Medicinal Chemistry, 2021, 217, 113340
DOI: 10.1016/j.ejmech.2021.113340

Aloe emodin-conjugated sulfonyl hydrazones as novel type of antibacterial modulators against S. aureus 25923 through multifaceted synergistic effects

Zhao Deng, Rammohan R. Yadav Bheemanaboina, Yan Luo and Cheng-He Zhou

Bioorganic Chemistry, 2022, 127, 106035
DOI: 10.1016/j.bioorg.2022.106035

Design and synthesis of aminothiazolyl norfloxacin analogues as potential antimicrobial agents and their biological evaluation

Liang-Liang Wang, Narsaiah Battini, Rammohan R.Yadav Bheemanaboina, Shao-Lin Zhang and Cheng-He Zhou

European Journal of Medicinal Chemistry, 2019, 167, 105
DOI: 10.1016/j.ejmech.2019.01.072

Natural Berberine-Hybridized Benzimidazoles as Novel Unique Bactericides against Staphylococcus aureus

Hang Sun, Mohammad Fawad Ansari, Bo Fang and Cheng-He Zhou

J. Agric. Food Chem., 2021, 69, 7831
DOI: 10.1021/acs.jafc.1c02545

Discovery of 3-indolylbenzoquinone derivatives with therapeutic potential for breast cancer

Mingli Hu, Lang Zheng, Ailing Li, Xiao Li, Wengxue Liang, Yuanhao Zhu, Aoxue Wang, Ling He, Xiuxiu Liu and Qiu Sun

Bioorganic & Medicinal Chemistry, 2025, 120, 118094
DOI: 10.1016/j.bmc.2025.118094

Identification of Novel Antifungal Skeleton of Hydroxyethyl Naphthalimides with Synergistic Potential for Chemical and Dynamic Treatments

Pengli Zhang, Vijai Kumar Reddy Tangadanchu and Chenghe Zhou

Molecules, 2022, 27, 8453
DOI: 10.3390/molecules27238453

Isatin-derived azoles as new potential antimicrobial agents: Design, synthesis and biological evaluation

Vijai Kumar Reddy Tangadanchu, Yan-Fei Sui and Cheng-He Zhou

Bioorganic & Medicinal Chemistry Letters, 2021, 41, 128030
DOI: 10.1016/j.bmcl.2021.128030

Novel aminophosphoryl hybridization of natural berberine and heterocyclic azoles with large potential to combat global increasing bacterial resistance

Yu Zhou, Ying Yang, Aisha Bibi, Wei-Wei Gao, Shao-Lin Zhang and Cheng-He Zhou

Bioorganic Chemistry, 2026, 174, 109725
DOI: 10.1016/j.bioorg.2026.109725

Synthetic strategies of phenazine derivatives: A review

Yu‐Xin Che, Xiao‐Ni Qi, Wen‐Juan Qu, Bing‐Bing Shi, Qi Lin, Hong Yao, You‐Ming Zhang and Tai‐Bao Wei

Journal of Heterocyclic Chem, 2022, 59, 969
DOI: 10.1002/jhet.4434

Discovery of indolylacryloyl-derived oxacins as novel potential broad-spectrum antibacterial candidates

Yue-Gao Hu, Narsaiah Battini, Bo Fang and Cheng-He Zhou

European Journal of Medicinal Chemistry, 2024, 270, 116392
DOI: 10.1016/j.ejmech.2024.116392

Comprehensive Insights Into Sulfanilamido‐Based Medicinal Design and Research

Yi‐Xin Wang, Juan Wang, Lin‐Li Mou, Hui‐Zhen Zhang, Guang‐Ying Chen and Cheng‐He Zhou

Medicinal Research Reviews, 2025, 45, 1700
DOI: 10.1002/med.22115

Identification of hydroxyphenyl cyanovinyl thiazoles as new structural scaffold of potential antibacterial agents

Xing Lu, Shao-Lin Zhang and Cheng-He Zhou

Bioorganic & Medicinal Chemistry Letters, 2025, 124, 130258
DOI: 10.1016/j.bmcl.2025.130258

An insight into the medicinal attributes of berberine derivatives: A review

Sobhi Gaba, Anjali Saini, Gurpreet Singh and Vikramdeep Monga

Bioorganic & Medicinal Chemistry, 2021, 38, 116143
DOI: 10.1016/j.bmc.2021.116143

Unique iminotetrahydroberberine-corbelled metronidazoles as potential membrane active broad-spectrum antibacterial agents

Mohammad Fawad Ansari, Yi-Min Tan, Hang Sun, Shuo Li and Cheng-He Zhou

Bioorganic & Medicinal Chemistry Letters, 2022, 76, 129012
DOI: 10.1016/j.bmcl.2022.129012