In situ photoacoustic imaging of cysteine to reveal the mechanism of limited GSH synthesis in pulmonary fibrosis

Hui Wang, Yixin Zhang, Yuyun Yang, Zixu He, Chuanchen Wu, Wei Zhang, Wen Zhang, Ju Liu, Ping Li and Bo Tang

Chem. Commun., 2019, 55, 9685
DOI: 10.1039/C9CC03814K

Lysosome-targeted two-photon fluorescent probes for rapid detection of H2S in live cells

Gongchun Li, Saige Ma, Jun Tang and Yong Ye

New J. Chem., 2019, 43, 1267
DOI: 10.1039/C8NJ05419C

A FRET-based ratiometric fluorescent probe to detect cysteine metabolism in mitochondria

Xiaojing Han, Zhiyao Zhai, Xiaopeng Yang, Di Zhang, Jun Tang, Jianming Zhu, Xiaofei Zhu and Yong Ye

Org. Biomol. Chem., 2020, 18, 1487
DOI: 10.1039/D0OB00002G

Rational design of a large Stokes shift xanthene–benzothiozolium dyad for probing cysteine in mitochondria

Songtao Cai, Qiuchen Liu, Chang Liu, Song He, Liancheng Zhao, Xianshun Zeng and Jin Gong

J. Mater. Chem. B, 2022, 10, 1265
DOI: 10.1039/D1TB02639A

Rational engineering of a recognition group to construct a two-photon reaction-based fluorescent probe for rapid and selective sensing of cysteine

Ziwei Zhang, Zhen Shi, Yumeng Yang, Junyong Sun and Feng Gao

Analyst, 2025, 150, 740
DOI: 10.1039/D4AN01468E

A lysosome-targetable fluorescent probe for the simultaneous sensing of Cys/Hcy and GSH from different emission channels

Hui Zhang, Lizhen Xu, Wenxiu Li, Wenqiang Chen, Qi Xiao, Jun Huang, Chusheng Huang, Jiarong Sheng and Xiangzhi Song

RSC Adv., 2019, 9, 7955
DOI: 10.1039/C9RA00210C

Endoplasmic reticulum targeted fluorescent probe for the detection of hydrogen sulfide based on a twist-blockage strategy

Yongru Zhang, Beibei Zhang, Zipeng Li, Lianbang Wang, Xueling Ren and Yong Ye

Org. Biomol. Chem., 2019, 17, 8778
DOI: 10.1039/C9OB01750J

Recent progress towards the development of fluorescent probes for the detection of disease-related enzymes

Lopamudra Mishra and Monalisa Mishra

J. Mater. Chem. B, 2025, 13, 763
DOI: 10.1039/D4TB01960A

A novel highly sensitive fluorescent probe for bioimaging biothiols and its applications in distinguishing cancer cells from normal cells

Hanchuang Zhu, Hanming Zhang, Changxu Liang, Caiyun Liu, Pan Jia, Zilu Li, Yamin Yu, Xue Zhang, Baocun Zhu and Wenlong Sheng

Analyst, 2019, 144, 7010
DOI: 10.1039/C9AN01760G

An ESIPT-induced NIR fluorescent probe to visualize mitochondrial sulfur dioxide during oxidative stress in vivo

Haixian Ren, Fangjun Huo, Xia Wu, Xiaogang Liu and Caixia Yin

Chem. Commun., 2021, 57, 655
DOI: 10.1039/D0CC07398A

Highly selective and sensitive fluorescent probe for the rapid detection of mercury ions

Zujun Xu, Wenxiu Shi, Chengjun Yang, Jing Xu, Huapeng Liu, Jing Xu and Baocun Zhu

RSC Adv., 2019, 9, 10554
DOI: 10.1039/C9RA00622B

The chronological evolution of small organic molecular fluorescent probes for thiols

Yongkang Yue, Fangjun Huo and Caixia Yin

Chem. Sci., 2021, 12, 1220
DOI: 10.1039/D0SC04960C

An efficient ruthenium(ii) tris(bipyridyl)-based chemosensor for the specific detection of cysteine and its luminescence imaging in living zebrafish

Yibin Li, Ningning Shi and Minna Li

New J. Chem., 2019, 43, 18517
DOI: 10.1039/C9NJ04426D

Dual-site functionalized NIR fluorescent material for a discriminative concentration-dependent response to SO2 in cells and mice

Weijie Zhang, Fangjun Huo, Yongbin Zhang and Caixia Yin

J. Mater. Chem. B, 2019, 7, 1945
DOI: 10.1039/C8TB03253J

A near-infrared fluorescent probe for the discrimination of cysteine in pure aqueous solution and imaging of cysteine in hepatocellular carcinoma cells with facile cell-compatible ability

Xin Yang and Ying Qian

New J. Chem., 2019, 43, 3725
DOI: 10.1039/C9NJ00129H

A paper-based chemosensor for highly specific, ultrasensitive, and instantaneous visual detection of toxic phosgene

Lintao Zeng, Hongyan Zeng, Shuangfei Wang, Shan Wang, Ji-Ting Hou and Juyoung Yoon

Chem. Commun., 2019, 55, 13753
DOI: 10.1039/C9CC07437F

A novel fluorescence probe for the selective detection of cysteine in aqueous solutions and imaging in living cells and mice

Huihui Mei, Dongmei Wang, Minghui Wang, Xin Gu, Xuejun Liu and Li Yang

Anal. Methods, 2021, 13, 1965
DOI: 10.1039/D1AY00178G

A novel NIR fluorescent probe for the double-site and ratiometric detection of SO2 derivatives and its applications

Jianming Zhu, Fengyun Qin, Di Zhang, Jun Tang, Wenya Liu, Wenbo Cao and Yong Ye

New J. Chem., 2019, 43, 16806
DOI: 10.1039/C9NJ03997J

A novel and effective benzo[d]thiazole-based fluorescent probe with dual recognition factors for highly sensitive and selective imaging of cysteine in vitro and in vivo

Meiqing Zhu, Xiaoqin Wu, Linfeng Sang, Fugang Fan, Lijun Wang, Xiangwei Wu, Rimao Hua, Yi Wang and Qing X. Li

New J. Chem., 2019, 43, 13463
DOI: 10.1039/C9NJ03202A

A mitochondria targetable near-infrared fluorescence probe for glutathione visual biological detection

Mingxuan Jia, Liangnian Wei, Yuxun Lu, Ruqiu Zhang, Qiuling Chen, Wenjiang Xia, Ye Liu, Fan Li and Ying Zhou

RSC Adv., 2022, 12, 2668
DOI: 10.1039/D1RA08917J

Functional synthetic probes for selective targeting and multi-analyte detection and imaging

Yongkang Yue, Fangjun Huo, Fangqin Cheng, Xijing Zhu, Tendai Mafireyi, Robert M. Strongin and Caixia Yin

Chem. Soc. Rev., 2019, 48, 4155
DOI: 10.1039/C8CS01006D

Imaging dynamic changes of an intracellular cysteine pool that responds to the stimulation of external oxidative stress

Kun Chen, Meng Zhang, Yalin Qi, Jing Fan, Xiang Ma, Hailiang Zhu and Yong Qian

Analyst, 2019, 144, 2320
DOI: 10.1039/C8AN02232A

Dual-channel red fluorescent probe for detection of Cys/Hcy and GSH in plants

Yongfei Huang, Yongbin Zhang, Fan gjun Huo, Yaoming Liu and Caixia Yin

Sensors and Actuators B: Chemical, 2019, 301, 127123
DOI: 10.1016/j.snb.2019.127123

A Single Fluorescent Chemosensor for Simultaneous Discriminative Detection of Gaseous Phosgene and a Nerve Agent Mimic

Lintao Zeng, Hongyan Zeng, Lirong Jiang, Shan Wang, Ji-Ting Hou and Juyoung Yoon

Anal. Chem., 2019, 91, 12070
DOI: 10.1021/acs.analchem.9b03230

Analyte-Induced Restriction of Intramolecular Rotation: Turn-On aza-BODIPY Sensor for Biothiol Detection in Aqueous Media

Bleda Can Sadikogullari and Ayse Daut Ozdemir

Org. Lett., 2025, 27, 9884
DOI: 10.1021/acs.orglett.5c02543

Recent advances in multifunctional fluorescent probes for viscosity and analytes

Xiaopeng Yang, Di Zhang, Yong Ye and Yufen Zhao

Coordination Chemistry Reviews, 2022, 453, 214336
DOI: 10.1016/j.ccr.2021.214336

A bifunctional fluorescent probe based on PET & ICT for simultaneously recognizing Cys and H2S in living cells

Huawei Niu, Yuhan Duan, Yuanyuan Zhang, Xinting Hua, Chuan Xu, Zhaozhou Li, Jinliang Ma, Fangyuan Qin, Yaping Zhai, Yong Ye and Yufen Zhao

Journal of Photochemistry and Photobiology B: Biology, 2022, 230, 112441
DOI: 10.1016/j.jphotobiol.2022.112441

A simple ratiometric fluorescent sensor selectively compatible of different combinations of characteristic groups for identification of glutathione, cysteine and homocysteine

Ying Wu, Yuhuan Zhang, Lan Wang, Yuchen Huyan, Hongjuan Li, Zhichao Pei, Yanfeng Tang, Shiguo Sun and Yongqian Xu

Sensors and Actuators B: Chemical, 2020, 302, 127181
DOI: 10.1016/j.snb.2019.127181

Recent advances in the development of responsive probes for selective detection of cysteine

Run Zhang, Jiaxi Yong, Jingli Yuan and Zhi Ping Xu

Coordination Chemistry Reviews, 2020, 408, 213182
DOI: 10.1016/j.ccr.2020.213182

A long-wavelength mitochondria-targeted fluorescent probe for imaging of peroxynitrite during dexamethasone treatment

Jun Tang, Ziyi Li, Chuchu Qiang, Yan Han, Lifang Yang, Li Zhu, Tan Dang, Gairong Chen and Yong Ye

Spectrochimica Acta Part A: Molecular and Biomolecular Spectroscopy, 2023, 292, 122429
DOI: 10.1016/j.saa.2023.122429

Mitochondria-targeted fluorescent probes for oxidative stress imaging

Huawei Niu, Keke Chen, Jiahui Xu, Xiaofei Zhu, Wenbo Cao, Zhenji Wang, Yong Ye and Yufen Zhao

Sensors and Actuators B: Chemical, 2019, 299, 126938
DOI: 10.1016/j.snb.2019.126938

Review on the recent progress in the development of fluorescent probes targeting enzymes

Asanka Amith Rajapaksha, Yi-Xuan Fu, Wu Yingzheng Guo, Shi-Yu Liu, Zhi-Wen Li, Cui-Qin Xiong, Wen-Chao Yang and Guang-Fu Yang

Methods Appl. Fluoresc., 2021, 9, 032001
DOI: 10.1088/2050-6120/abf988

A New Strategy: Distinguishable Multi-substance Detection, Multiple Pathway Tracing Based on a New Site Constructed by the Reaction Process and Its Tumor Targeting

Yongfei Huang, Yongbin Zhang, Fangjun Huo, Jianbin Chao, Fangqin Cheng and Caixia Yin

J. Am. Chem. Soc., 2020, 142, 18706
DOI: 10.1021/jacs.0c10210

A Bifunctional Fluorescent Probe for Imaging Lipid Droplets Polarity/So2 During Ferroptosis

peiyao xie, jianfei liu, xiaopeng yang, Weimin Zhu and Yong Ye

SSRN Journal, 2022
DOI: 10.2139/ssrn.4064682

A novel naphthalimide-based fluorescent probe for the colorimetric and ratiometric detection of SO2 derivatives in biological imaging

Linlin Yang, Nan Yang, Pengli Gu, Yihua Zhang, Xianyu Gong, Shichao Zhang, Junwan Li, Liguo Ji and Guangjie He

Bioorganic Chemistry, 2022, 123, 105801
DOI: 10.1016/j.bioorg.2022.105801

Developing a julolidine-fluorescein-based hybrid as a highly sensitive fluorescent probe for sensing and bioimaging cysteine in living cells

Yuan Ji, Fang Dai and Bo Zhou

Talanta, 2019, 197, 631
DOI: 10.1016/j.talanta.2019.01.084

Simultaneous detection of cysteine and glutathione in food with a two-channel near-infrared fluorescent probe

Xichao Hu, Ruizhe Duan, Jiali Wang, Mingchao Li, Hong Chen, Jin Zhang and Lintao Zeng

Spectrochimica Acta Part A: Molecular and Biomolecular Spectroscopy, 2025, 325, 125098
DOI: 10.1016/j.saa.2024.125098

A versatile aggregation-induced emission probe: Accurate quantification, on-site detection, and bioimaging of sulfur dioxide derivatives using a colorimetric and near-infrared fluorescent probe

Xiaoyan Su, Ruifeng Zeng, Xianxian Huang, Jinshuai Lan, Zhe Li, Zhiming Yan, Chunli Tang, Lin Jing, Yue Ding, Tong Zhang and Neng Jiang

Talanta, 2026, 298, 128953
DOI: 10.1016/j.talanta.2025.128953

Mitochondria-Anchored Colorimetric and Ratiometric Fluorescent Chemosensor for Visualizing Cysteine/Homocysteine in Living Cells and Daphnia magna Model

Mingwang Yang, Jiangli Fan, Wen Sun, Jianjun Du and Xiaojun Peng

Anal. Chem., 2019, 91, 12531
DOI: 10.1021/acs.analchem.9b03386

Ratiometric Nanoparticle Array-Based Near-Infrared Fluorescent Probes for Quantitative Protein Sensing

Xiaohan Wang, Xiaotao Zhao, Kai Zheng, Xuhong Guo, Yunfeng Yan and Yisheng Xu

Langmuir, 2019, 35, 5599
DOI: 10.1021/acs.langmuir.9b00788

A highly sensitive rapid-response fluorescent probe for specifically tracking endogenous labile Fe2+ in living cells and zebrafish

Xue Zhang, Yanan Chen, Xinyu Cai, Caiyun Liu, Pan Jia, Zilu Li, Hanchuang Zhu, Yamin Yu, Kun Wang, Xiwei Li, Wenlong Sheng and Baocun Zhu

Dyes and Pigments, 2020, 174, 108065
DOI: 10.1016/j.dyepig.2019.108065

Fluorescent Imaging for Cysteine Detection In Vivo with High Selectivity

Zhuwen Duan, Youming Zhu, Yuyun Yang, Zixu He, Ju Liu, Ping Li, Hui Wang and Bo Tang

ChemistryOpen, 2019, 8, 316
DOI: 10.1002/open.201900045

A novel fluorescent probe with dual-sites for simultaneously monitoring metabolisms of cysteine in living cells and zebrafishes

Guoxing Yin, Ting Yu, Yabing Gan, Li Zhou, Meiling Liu, Youyu Zhang, Haitao Li, Peng Yin and Shouzhuo Yao

Spectrochimica Acta Part A: Molecular and Biomolecular Spectroscopy, 2020, 241, 118602
DOI: 10.1016/j.saa.2020.118602

A FRET‐Based Near‐Infrared Fluorescent Probe for Ratiometric Detection of Cysteine in Mitochondria

Shuai Xia, Yibin Zhang, Mingxi Fang, Logan Mikesell, Tessa E. Steenwinkel, Shulin Wan, Tyler Phillips, Rudy L. Luck, Thomas Werner and Haiying Liu

ChemBioChem, 2019, 20, 1986
DOI: 10.1002/cbic.201900071

A highly sensitive and fast responsive fluorescent probe for SO2 derivatives and its application in living cell imaging

Mengsheng Xu, Le Wang, Man Li, Zhiwei Ma, Di Zhang and Jihong Liu

Phosphorus, Sulfur, and Silicon and the Related Elements, 2020, 195, 842
DOI: 10.1080/10426507.2020.1759061

Dual-Site Fluorescent Sensor as a Multiple Logic System for Studying the Dichotomous Function of Sulfur Dioxide under Oxidative Stress Induced by Peroxynitrite

Xuerui Song, Yanxuan Guo, Chunlin Jing, Yan Feng, Chen Cao, Manchang Kou, Weisheng Liu and Degui Wang

Anal. Chem., 2022, 94, 5744
DOI: 10.1021/acs.analchem.1c03792

Silica-embedded CdTe quantum dots functionalized with rhodamine derivative for instant visual detection of ferric ions in aqueous media

Yunsuo Kuang, Xiang Wang, Xike Tian, Chao Yang, Yong Li and Yulun Nie

Journal of Photochemistry and Photobiology A: Chemistry, 2019, 372, 140
DOI: 10.1016/j.jphotochem.2018.12.015

Recent advances in small molecule fluorescent probes for simultaneous imaging of two bioactive molecules in live cells and in vivo

Yongqing Zhou, Xin Wang, Wei Zhang, Bo Tang and Ping Li

Front. Chem. Sci. Eng., 2022, 16, 4
DOI: 10.1007/s11705-021-2041-2

A fluorescent probe with dual acrylate sites for discrimination of different concentration ranges of cysteine in living cells

Zhongyong Xu, Shufan Si, Zhijun Zhang, Huiya Tan, Tianyi Qin, Zhonglin Wang, Dong Wang, Lei Wang and Bin Liu

Analytica Chimica Acta, 2021, 1176, 338763
DOI: 10.1016/j.aca.2021.338763

A two-photon fluorescent probe for imaging of mitochondrial cysteine in λ-carrageenan induced arthritis

Hui Wang, Hongtong Wang, Xiaoting Zhang, Mingyan Dong, Fang Huang, Ping Li and Bo Tang

Sensors and Actuators B: Chemical, 2021, 338, 129749
DOI: 10.1016/j.snb.2021.129749

Recent progress in the development of fluorescent probes for detection of biothiols

Jianan Dai, Chenggong Ma, Ping Zhang, Yongqian Fu and Baoxing Shen

Dyes and Pigments, 2020, 177, 108321
DOI: 10.1016/j.dyepig.2020.108321

Development and applications of a coumarin-based “turn-on” fluorescent probe for effectively discriminating reduced glutathione from homocysteine and cysteine in living cells and organisms

Xiaoyi Qi, Lichao Shang, Sicheng Liang, Hao Li, Jing Chen, Chen Xin, Jing Zhao, Mingming Deng, Qingying Wang, Qing He, Muhan Lv, Alexander Tobias Teichmann, Zhongqiong Wang and Youzhe Yang

Dyes and Pigments, 2021, 194, 109625
DOI: 10.1016/j.dyepig.2021.109625

Regulation of mitochondrial function as a promising target in platelet activation-related diseases

Eduardo Fuentes, Ramiro Araya-Maturana and Félix A. Urra

Free Radical Biology and Medicine, 2019, 136, 172
DOI: 10.1016/j.freeradbiomed.2019.01.007

A highly specific Golgi-targetable fluorescent probe for tracking cysteine generation during the Golgi stress response

Xue Zhang, Caiyun Liu, Xinyu Cai, Bin Tian, Hanchuang Zhu, Yanan Chen, Wenlong Sheng, Pan Jia, Zilu Li, Yamin Yu, Shengyun Huang and Baocun Zhu

Sensors and Actuators B: Chemical, 2020, 310, 127820
DOI: 10.1016/j.snb.2020.127820

A lysosome-targetable multifunctional fluorescent probe based on intramolecular NH…NH2 hydrogen bonding for detection of hypochlorite and cyanides

Aoran Kan, Yingmei Cao, Qiunan She, Yicong Zhou, Yingming Tan, Jie Yang, Jinwu Yan, Zhenjiang Liu and Chuanxiang Liu

Spectrochimica Acta Part A: Molecular and Biomolecular Spectroscopy, 2025, 338, 126180
DOI: 10.1016/j.saa.2025.126180

A multifunctional near-infrared fluorescence probe with multi-reactive sites for real-time tracking Cys to SO2 and GSH to SO2 metabolism in vivo

Haibo Liu, Min You, Xuyu Feng, Jialiang Chen, Bin Li, Zhigang Gao, Haizhu Xing, Zhongjian Cong, Baojing Zhou, Jing Zhu and Mingjie Jin

Sensors and Actuators B: Chemical, 2024, 400, 134870
DOI: 10.1016/j.snb.2023.134870

Design and Screening of Fluorescent Probes Based upon Hemicyanine Dyes to Sensitively Respond to HSO3– in Living Cells

Bu-yue Zhang, Xiu-feng Zhang, Xiao-ying Ma, Da-wei Yang, Hong-xia Sun, Ya-lin Tang and Lei Shi

J. Org. Chem., 2023, 88, 9959
DOI: 10.1021/acs.joc.3c00715

Fluorescent Probes for Live Cell Thiol Detection

Shenggang Wang, Yue Huang and Xiangming Guan

Molecules, 2021, 26, 3575
DOI: 10.3390/molecules26123575

Cysteine triggered cascade reaction forming coumarin: Visualization of cysteine fluctuation in alcoholic liver disease by a NIR fluorescent probe

Lei Shen, Ming Ma, Keyan Zhou, Ming Jin, Shuxiang Wang, Hongmei Liu and Yutao Yang

Spectrochimica Acta Part A: Molecular and Biomolecular Spectroscopy, 2025, 324, 124974
DOI: 10.1016/j.saa.2024.124974

Diagnostic and Therapeutic Integration Prodrug: Dynamic Probe Engineering via Cys/GSH Depletion to Amplify Type I Photodynamic Therapy for Breast Cancer

Yongfei Huang, Junping Liang, Wenbo Lu, Chenzhong Li and Zhefeng Fan

Anal. Chem., 2025, 97, 17175
DOI: 10.1021/acs.analchem.5c03328

Rational Design of Near-Infrared Cyanine-Based Fluorescent Probes for Rapid In Vivo Sensing Cysteine

Hehe Zhang, Chenxu Yan, Hui Li, Lei Shi, Ruofei Wang, Zhiqian Guo and Wei-Hong Zhu

ACS Appl. Bio Mater., 2021, 4, 2001
DOI: 10.1021/acsabm.0c00260

A new isothiocyanate-based Golgi-targeting fluorescent probe for Cys and its bioimaging applications during the Golgi stress response

Hanchuang Zhu, Caiyun Liu, Xiaodi Rong, Yan Zhang, Meijun Su, Xin Wang, Mengyuan Liu, Xiaohui Zhang, Wenlong Sheng and Baocun Zhu

Bioorganic Chemistry, 2022, 122, 105741
DOI: 10.1016/j.bioorg.2022.105741

Biheterocyclic Coumarins: A Simple Yet Versatile Resource for Futuristic Design and Applications in Bio-molecular and Material Chemistry

Ashish Anand, Netravati Khanapurmath, Manohar V. Kulkarni and Tayur N. Guru Row

COC, 2022, 26, 444
DOI: 10.2174/1385272826666220301124149

Facile construction of imidazole functionalized polysiloxanes by thiol-ene “Click” reaction for the consecutive detection of Fe3+ and amino acids

Yujing Zuo, Yu Zhang, Zhiming Gou and Weiying Lin

Sensors and Actuators B: Chemical, 2019, 291, 235
DOI: 10.1016/j.snb.2019.04.021

Endoplasmic reticulum-targetable fluorescent probe for visualizing HClO in EC1 cells

Jianfei Liu, Zhiyao Zhai, Huawei Niu, Yongru Zhang, Xiangzhi Song, Panke Zhang and Yong Ye

Tetrahedron Letters, 2020, 61, 152301
DOI: 10.1016/j.tetlet.2020.152301

Coumarin-based near-infrared fluorogenic probes: Recent advances, challenges and future perspectives

Yufan Fan, Yue Wu, Jie Hou, Ping Wang, Xiaojun Peng and Guangbo Ge

Coordination Chemistry Reviews, 2023, 480, 215020
DOI: 10.1016/j.ccr.2023.215020

A mitochondrial targeted dual ratiometric near-infrared fluorescent probe based on ICT effect for the detection of SO2 derivative and its bioimaging

Kangshuo Xu, Na Tang, Furong Liu, Yin Ai, Haichang Ding, Congbin Fan, Gang Liu and Shouzhi Pu

Spectrochimica Acta Part A: Molecular and Biomolecular Spectroscopy, 2024, 317, 124415
DOI: 10.1016/j.saa.2024.124415

A dual-channel fluorescent nanoprobe for accurate cancer diagnosis by sequential detection of adenosine triphosphate and sulfur dioxide

Mei-Jia Hou, Zhi-Qing Wang, Jun-Tao Chen, Zhi-Ke Tan, Guo-Jiang Mao, Dong-Hua Chen, Yongfei Li and Chun-Yan Li

Talanta, 2023, 265, 124815
DOI: 10.1016/j.talanta.2023.124815

Development of a water-soluble near-infrared fluorescent probe for endogenous cysteine imaging

Yiling Li, Xu He, Yibing Huang, Longbin Xu, Lihe Zhao, Xiaolei Li, Ying Sun, Xinghua Wang, Pinyi Ma and Daqian Song

Spectrochimica Acta Part A: Molecular and Biomolecular Spectroscopy, 2020, 226, 117544
DOI: 10.1016/j.saa.2019.117544

A multi-signal mitochondria-targetable fluorescent probe for simultaneously discriminating Cys/Hcy/H2S, GSH, and SO2 and visualizing the endogenous generation of SO2 in living cells

Ya-Long Zheng, Zuo-Hu Chai, Wei Tang, Shuai Yan, Fang Dai and Bo Zhou

Sensors and Actuators B: Chemical, 2021, 330, 129343
DOI: 10.1016/j.snb.2020.129343

Mitochondria-Targeted New Blue Light-Emitting Fluorescent Molecular Probe

Saswat Mohapatra, Gaurav Das, Chirantan Kar, Masashi Nitani, Yutaka Ie, Yoshio Aso and Surajit Ghosh

ACS Omega, 2019, 4, 9361
DOI: 10.1021/acsomega.8b03331

Review of Hydrogen Sulfide Based on Its Activity Mechanism and Fluorescence Sensing

Jinlong Zhang, Quan Jing, Fei Gao, Fuxin Zhang, Dong Pei, Duolong Di and Jun Hai

Targets, 2024, 2, 202
DOI: 10.3390/targets2030012

Aggregation-disaggregation-switched sensing strategy for copper(II) ion and histidine in aqueous solution and living cell imaging

Qian Zhang, Peng Zhang, Shasha Li, Caixia Fu and Caifeng Ding

Dyes and Pigments, 2019, 171, 107697
DOI: 10.1016/j.dyepig.2019.107697

Hemicyanine-Based Fluorescent Probe for Distinguishing Cysteine in Living HeLa Cells

Linqiang Niu, Yang Luo, Haoran Zhao, Qijuan Cao, Jiamin Wang and Jianhong Wang

Analytical Letters, 2021, 54, 2666
DOI: 10.1080/00032719.2021.1881534

A bifunctional fluorescent probe for imaging lipid droplets polarity/SO2 during ferroptosis

Peiyao Xie, Jianfei Liu, Xiaopeng Yang, Weimin Zhu and Yong Ye

Sensors and Actuators B: Chemical, 2022, 365, 131937
DOI: 10.1016/j.snb.2022.131937

Deep-red/NIR emitting coumarin derivatives - Synthesis, photophysical properties, and biological applications

Suryapratap J. Sharma and Nagaiyan Sekar

Dyes and Pigments, 2022, 202, 110306
DOI: 10.1016/j.dyepig.2022.110306

The exquisite integration of ESIPT, PET and AIE for constructing fluorescent probe for Hg(II) detection and poisoning

Xiang Cheng, Shuai Huang, Qian Lei, Fei Chen, Fan Zheng, Shibo Zhong, Xueyan Huang, Bin Feng, Xueping Feng and Wenbin Zeng

Chinese Chemical Letters, 2022, 33, 1861
DOI: 10.1016/j.cclet.2021.10.024

Assessment of environmental and biological stress using mitochondria-targeted red-emitting and near-infrared fluorescent probes for biothiol analysis: a review

Wen-Yu Lu, Hui-Jing Li and Yan-Chao Wu

Environ Chem Lett, 2024, 22, 3135
DOI: 10.1007/s10311-024-01761-z

Hydro-soluble NIR fluorescent probe with multiple sites and multiple excitations for distinguishing visualization of endogenous Cys/Hcy, and GSH

Yang Yang, Yan Feng, Hao Li, Rong Shen, Yingzhe Wang, Xuerui Song, Chen Cao, Guolin Zhang and Weisheng Liu

Sensors and Actuators B: Chemical, 2021, 333, 129189
DOI: 10.1016/j.snb.2020.129189

A new ratiometric AIE fluorescent probe for detecting cysteine in food samples and imaging in the biological system

Shuai Gong, Ahui Qin, Yan Zhang, Mingxin Li, Xiaoyi Chen, Yueyin Liang, Xu Xu, Zhonglong Wang and Shifa Wang

Food Chemistry, 2023, 400, 134108
DOI: 10.1016/j.foodchem.2022.134108

A sequential dual-key-dual-lock fluorescent probe for detection of SO2 and H2O2 in cells and mice

Ying Fang, Jun Wang, Hui Yu, Qi Zhang, Shaojin Chen, Kun-Peng Wang and Zhi-Qiang Hu

Sensors and Actuators B: Chemical, 2022, 371, 132514
DOI: 10.1016/j.snb.2022.132514

An ICT-based fluorescent probe guided by theoretical calculation for selectively mapping endogenous GSH in living cells

Jiao Chen, Yiwei Li, Xukai Feng, Mengyao She, Wenxin Yao, Xin Leng, Ping Liu, Shengyong Zhang and Jianli Li

Spectrochimica Acta Part A: Molecular and Biomolecular Spectroscopy, 2021, 246, 119041
DOI: 10.1016/j.saa.2020.119041

Design and synthesis of a novel fluorescent probe for the detection of bisulfite in plant and zebrafish

Fei Luo, Yuhang Ji, Shiyi Zhang, Ziting Gao, Baoshun Jia, Zhixin Li, Jianbo Chang, Miao Lai, Xiaopeng Yang and Xiaoming Ji

Journal of Molecular Structure, 2024, 1297, 136971
DOI: 10.1016/j.molstruc.2023.136971

In vivo tracking cystine/glutamate antiporter-mediated cysteine/cystine pool under ferroptosis

Zhen Li, Yan Li, Yushun Yang, Zhiyuan Gong, Hailiang Zhu and Yong Qian

Analytica Chimica Acta, 2020, 1125, 66
DOI: 10.1016/j.aca.2020.05.049

A novel dual-channel fluorescent probe for nitroxyl detection and its application in HepG-2 cells

Zipeng Li, Jie Li, Di Zhang, Xiaofei Zhu, Yong Ye and Yufen Zhao

Sensors and Actuators B: Chemical, 2020, 312, 127944
DOI: 10.1016/j.snb.2020.127944

A Sequential Dual-Key-Dual-Lock Fluorescent Probe for Detection of So2 and H2o2 in Cell and Mice

Ying Fang, Jun Wang, Hui Yu, Qi Zhang, Shaojin Chen, Kun-Peng Wang and Zhi-Qiang Hu

SSRN Journal, 2022
DOI: 10.2139/ssrn.4072694

“Turn-on” fluorescent probe for selective Cys recognition and the related mechanism

Yulian Duan, Gao-zhang Gou, Jianbin Xu, Yubo Hu and Feixiang Cheng

Journal of Photochemistry and Photobiology A: Chemistry, 2019, 379, 1
DOI: 10.1016/j.jphotochem.2019.05.003

A dual-fluorophore and dual-site multifunctional fluorescent sensor for real-time visualization of mitochondrial ONOO-/GSH cross-talk in living cells

Chunlin Jing, Yingzhe Wang, Xuerui Song, Xinxin Li, Yan Feng, Manchang Kou, Guolin Zhang, Wei Dou and Weisheng Liu

Sensors and Actuators B: Chemical, 2022, 365, 131847
DOI: 10.1016/j.snb.2022.131847

Triple-Channel fluorescent probe for simultaneous detection of Cys, SO₂, and H₂S to discriminate Cancer cells via Transsulfuration pathway metabolic profiling

Xin Jiang, Bo Liu, Yang Li, Haoyu Jin, Tianpeng Zhong, Ting Yu, Han Tang, Xiaorui Liu, Danqing Xu, Yuquan Tang, Youyu Zhang, Haitao Li, Huijun Zhou and Peng Yin

Spectrochimica Acta Part A: Molecular and Biomolecular Spectroscopy, 2026, 347, 127025
DOI: 10.1016/j.saa.2025.127025

Mitochondria-targeted fluorescent probe for rapid detection of thiols and its application in bioimaging

Yuedong Zhu, Haiting Pan, Yanyan Song, Chao Jing, Jia-An Gan and Junji Zhang

Dyes and Pigments, 2021, 191, 109376
DOI: 10.1016/j.dyepig.2021.109376

Changes in Biothiol Levels Are Closely Associated with Alzheimer’s Disease

Hui Han, Feng Wang, Juanjuan Chen, Xingxing Li, Gaoqing Fu, Jiawei Zhou, Dongsheng Zhou, Wei Wu and Haimin Chen

JAD, 2021, 82, 527
DOI: 10.3233/JAD-210021

A novel 2,5-bis(benzo[d]thiazol-2-yl)phenol scaffold-based ratiometric fluorescent probe for sensing cysteine in aqueous solution and serum

Meng Li, Kaibo Zheng, Hui Chen, Xiang Liu, Shuzhang Xiao, Jiaying Yan, Xuecai Tan and Nuonuo Zhang

Spectrochimica Acta Part A: Molecular and Biomolecular Spectroscopy, 2019, 217, 1
DOI: 10.1016/j.saa.2019.03.033

Reaction-based small-molecule fluorescent probes for endoplasmic reticulum- and mitochondria-targeted biosensing and bioimaging

Abdul Hadi Mehmood, Faiz Ullah, Baoli Dong and Hong Liu

Sci. China Mater., 2024, 67, 3491
DOI: 10.1007/s40843-024-3097-4

A bond energy transfer based difunctional fluorescent sensor for Cys and bisulfite

Fangfang Zhao, Zhiyao Zhai, Jun Tang, Beibei Zhang, Xiaopeng Yang, Xiangzhi Song and Yong Ye

Talanta, 2020, 214, 120884
DOI: 10.1016/j.talanta.2020.120884

Developing an aurone-based colorimetric fluorescent probe for fast cysteine sensing in foods, test strips and biological imaging

Xiaoyan Cao, Yichi Zhang, Jialing Hu, Yifan Wei, Yingyue Ding, Yanfei Kang, Chuanqing Ren and Qin Wang

Spectrochimica Acta Part A: Molecular and Biomolecular Spectroscopy, 2025, 338, 126226
DOI: 10.1016/j.saa.2025.126226

A novel activatable AIEgen fluorescent probe for peroxynitrite detection and its application in EC1 cells

Xiaojing Han, Xiaopeng Yang, Yongru Zhang, Zipeng Li, Wenbo Cao, Di Zhang and Yong Ye

Sensors and Actuators B: Chemical, 2020, 321, 128510
DOI: 10.1016/j.snb.2020.128510

Dual-binding benzene and rhodamine B conjugate derivatives as fluorescent chemodosimeter for hypochlorite in living cell imaging

Di Zhang, Zhiwei Ma, Yanliang Wang, Haiyan Yin, Man Li, Yun Wang, Hongqi Wang, Bin Jia and Jihong Liu

Spectrochimica Acta Part A: Molecular and Biomolecular Spectroscopy, 2020, 229, 117908
DOI: 10.1016/j.saa.2019.117908

Lysosome-targeted near-infrared fluorescent dye and its application in designing of probe for sensitive detection of cysteine in living cells

Qiuchen Liu, Chang Liu, Xiaojie Jiao, Songtao Cai, Song He, Liancheng Zhao, Xianshun Zeng and Tianhui Wang

Dyes and Pigments, 2021, 190, 109293
DOI: 10.1016/j.dyepig.2021.109293

An innovative hypochlorite-sensing scaffold and its imaging application in vivo

Yongfei Huang, Yongbin Zhang, Fangjun Huo and Caixia Yin

Dyes and Pigments, 2021, 191, 109378
DOI: 10.1016/j.dyepig.2021.109378

Mitochondria-targeted NIR fluorescent probe for sensing Hg2+/HSO3− and its intracellular applications

Jianfei Liu, Jie Li, Jun Tang, Xiaopeng Yang, Di Zhang, Yong Ye and Yufen Zhao

Talanta, 2021, 234, 122606
DOI: 10.1016/j.talanta.2021.122606

Rapid detection of SO2 in living cells and zebrafish by using an efficient near-infrared ratiometric fluorescent probe with large emission shift

Linlin Wang, Linlu Zhao, Zhencai Xu, Yingying Ma, Xiaofeng Wang, Qi Sun and Heng Liu

Microchemical Journal, 2021, 160, 105703
DOI: 10.1016/j.microc.2020.105703

Highly Selective and Sensitive Detection of Biogenic Defense Phytohormone Salicylic Acid in Living Cells and Plants Using a Novel and Viable Rhodamine-Functionalized Fluorescent Probe

Lin-Lin Yang, Si-Yan Zou, Yi-Hong Fu, Wen Li, Xiao-Peng Wen, Pei-Yi Wang, Zhen-Chao Wang, Gui-Ping Ouyang, Zhong Li and Song Yang

J. Agric. Food Chem., 2020, 68, 4285
DOI: 10.1021/acs.jafc.9b06771

Simultaneous Visualization of Endogenous Homocysteine, Cysteine, Glutathione, and their Transformation through Different Fluorescence Channels

Guoxing Yin, Tingting Niu, Ting Yu, Yabing Gan, Xinyu Sun, Peng Yin, Haimin Chen, Youyu Zhang, Haitao Li and Shouzhuo Yao

Angewandte Chemie, 2019, 131, 4605
DOI: 10.1002/ange.201813935

Simple and Commercially Available 6-chloroimidazo[1,2-a]pyridine-2-carboxylic Acid-based Fluorescent Probe for Monitoring pH Changes

Yunlong Gao, Guangle Song, Guowei Shi, Jixiang Xiao, Chunhao Yuan and Yanqing Ge

J Fluoresc, 2023, 33, 305
DOI: 10.1007/s10895-022-03086-y

Insight into sulfur dioxide and its derivatives metabolism in living system with visualized evidences via ultra-sensitive fluorescent probe

Xia Zhang, Li Zhang, Shudi Liu, Xiaozhen Zhu, Panpan Zhou, Xinyan Cheng, Renjie Zhang, Liangwei Zhang and Lingxin Chen

Journal of Hazardous Materials, 2022, 423, 127179
DOI: 10.1016/j.jhazmat.2021.127179

Photostable Fluorescent Tracker for Imaging Mitochondria with Super Resolution

Qichao Yao, Liuju Li, Xiaoshuai Huang, Haidong Li, Yanyun Fang, Jing Xia, Jiangli Fan, Liangyi Chen, Jingyun Wang and Xiaojun Peng

Anal. Chem., 2019, 91, 15777
DOI: 10.1021/acs.analchem.9b04065

A fluorescent probe for the dual detection of mercury ions and thiols based on a simple coumarin derivative

Pei Tao, Dongling Chen, Zhenxiang Xu, Yanxi Song, Hongqi Li and Chunying Xian

Coloration Technology, 2020, 136, 75
DOI: 10.1111/cote.12447

A lysosome targeting probe based on fluorescent protein chromophore for selectively detecting GSH and Cys in living cells

Baoxing Shen, Wenyu Zhu, Xu Zhi and Ying Qian

Talanta, 2020, 208, 120461
DOI: 10.1016/j.talanta.2019.120461

Simultaneous Visualization of Endogenous Homocysteine, Cysteine, Glutathione, and their Transformation through Different Fluorescence Channels

Guoxing Yin, Tingting Niu, Ting Yu, Yabing Gan, Xinyu Sun, Peng Yin, Haimin Chen, Youyu Zhang, Haitao Li and Shouzhuo Yao

Angew Chem Int Ed, 2019, 58, 4557
DOI: 10.1002/anie.201813935

A mitochondria-targetable fluorescent probe for sulfur dioxide detection and visualisation in living cells

Yuting Du, Caixia Pan and Chunjuan Cao

Spectrochimica Acta Part A: Molecular and Biomolecular Spectroscopy, 2023, 290, 122275
DOI: 10.1016/j.saa.2022.122275

Imaging Hg2+-Induced Oxidative Stress by NIR Molecular Probe with “Dual-Key-and-Lock” Strategy

Xiaopeng Yang, Xiaojing Han, Yongru Zhang, Jianfei Liu, Jun Tang, Di Zhang, Yufen Zhao and Yong Ye

Anal. Chem., 2020, 92, 12002
DOI: 10.1021/acs.analchem.0c02509

A rhodol-derived probe for intracellular biothiols imaging and rapid labelling of sulfhydryl-containing proteins

Shiyue Zheng, Junqian Peng, Long Jiang, Hao Gu, Fang Wang, Chongqing Wang, Sheng Lu and Xiaoqiang Chen

Sensors and Actuators B: Chemical, 2022, 367, 132148
DOI: 10.1016/j.snb.2022.132148

Fluorescent probes for lighting up ferroptotic cell death: A review

Xiaopeng Yang, Shiyi Zhang, Miao Lai, Xiaoming Ji, Yong Ye, Jun Tang, Xinyuan Liu and Mingqin Zhao

Talanta, 2023, 260, 124628
DOI: 10.1016/j.talanta.2023.124628

Coumarin-Based Small-Molecule Fluorescent Chemosensors

Duxia Cao, Zhiqiang Liu, Peter Verwilst, Seyoung Koo, Paramesh Jangjili, Jong Seung Kim and Weiying Lin

Chem. Rev., 2019, 119, 10403
DOI: 10.1021/acs.chemrev.9b00145

A highly selective colorimetric and fluorescent probe for cysteine sensing: Application in live cell imaging and test strips

Xiaoxia Chen, Xiaoqin Huang, Gang Liu, Yayi Tu, Congbin Fan and Shouzhi Pu

Dyes and Pigments, 2021, 196, 109810
DOI: 10.1016/j.dyepig.2021.109810

Recent design strategies and applications of small molecule fluorescent probes for food detection

Peng Zhang, Jiali Su, Hui Zhen, Tong Yu, Liangchen Wei, Mingyue Zheng, Chaoyuan Zeng and Wei Shu

Coordination Chemistry Reviews, 2025, 522, 216232
DOI: 10.1016/j.ccr.2024.216232

Visualization of biothiols and HClO in cancer therapy via a multi-responsive fluorescent probe

Xiaopeng Yang, Jianfei Liu, Peiyao Xie, Xiaojing Han, Di Zhang, Yong Ye and Yufen Zhao

Sensors and Actuators B: Chemical, 2021, 347, 130620
DOI: 10.1016/j.snb.2021.130620