The Wieland–Miescher ketone (WMK) has cemented its position as a cornerstone in the field of total synthesis, enabling the efficient construction of complex and bioactive natural products.
Euphorlactone A (1), a rearranged ent-atisane norditerpenoid with an undescribed 3-nor-2,4-olide-ent-atisane scaffold, and euphorlactone B (2), a new ent-atisane diterpenoid with an unprecedented seven-membered lactone ring C, were isolated from the roots of Euphorbia fischeriana.
Atisine-type C20-diterpenoid alkaloids are a very important class of diterpenoid alkaloids, which possess high chemical and biological diversity.
Lasiodiplodia is a prominent genus within the Botryosphaeriaceae family which is known as a plant pathogen. Species of Lasiodiplodia are prolific sources of bioactive secondary metabolites.