Development of a microfluidic cell transfection device into gene-edited CAR T cell manufacturing workflow

Tong Yu, Navdeep Jhita, Peter Shankles, Andrew Fedanov, Noah Kramer, Sunil S. Raikar and Todd Sulchek

Lab Chip, 2023, 23, 4804
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Efficient electroporation in primary cells with PEDOT:PSS electrodes

Asmaysinh A. Gharia, Clinton J. Bradfield, Elise P. W. Jenkins, Iain D. C. Fraser and George G. Malliaras

Sci. Adv., 2024, 10
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Developing CAR-immune cell therapy against SARS-CoV-2: Current status, challenges and prospects

Yizhao Chen, Chong Liu, Yilong Fang, Weile Chen, Jiaqi Qiu, Mengjuan Zhu, Wei Wei and Jiajie Tu

Biochemical Pharmacology, 2024, 222, 116066
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A Digital Microfluidic Platform for the Microscale Production of Functional Immune Cell Therapies

Samuel R. Little, Niloufar Rahbari, Mehri Hajiaghayi, Fatemeh Gholizadeh, Fanny-Mei Cloarec-Ung, Joel Phillips, Hugo Sinha, Alison Hirukawa, David J.H.F. Knapp, Peter J. Darlington and Steve C. C. Shih

Anal. Chem., 2025, 97, 11026
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Chimeric antigen receptor therapy meets mRNA technology

Jiacai Wu, Weigang Wu, Boping Zhou and Bin Li

Trends in Biotechnology, 2024, 42, 228
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Targeted CD7 CAR T-cells for treatment of T-Lymphocyte leukemia and lymphoma and acute myeloid leukemia: recent advances

Jile Liu, Yi Zhang, Ruiting Guo, Yifan Zhao, Rui Sun, Shujing Guo, Wenyi Lu and Mingfeng Zhao

Front. Immunol., 2023, 14
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Beyond Conventional Treatments: Exploring CAR-T Cell Therapy for Cancer Stem Cell Eradication

Lobna E. Rabie, Ahmed A. Mohran, Kholoud A. Gaber, Nour M. Ali, Asmaa M. Abd El Naby, Eman A. Ghoniem, Basmala A. Abd Elmaksod and Ahmed N. Abdallah

Stem Cell Rev and Rep, 2024, 20, 2001
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Chimeric antigen receptor-engineered (CAR)-T cell therapy for metastatic prostate cancer

Leah Tharian, Shiv Verma, Daniel Feinberg, Reshmi Parameswaran and Sanjay Gupta

Cancer Letters, 2025, 632, 217986
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Tumor buster - where will the CAR-T cell therapy ‘missile’ go?

Chunrun Qu, Hao Zhang, Hui Cao, Lanhua Tang, Haoyang Mo, Fangkun Liu, Liyang Zhang, Zhenjie Yi, Lifu Long, Luzhe Yan, Zeyu Wang, Nan Zhang, Peng Luo, Jian Zhang, Zaoqu Liu, Weijie Ye, Zhixiong Liu and Quan Cheng

Mol Cancer, 2022, 21
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A Tri‐Droplet Liquid Structure for Highly Efficient Intracellular Delivery in Primary Mammalian Cells Using Digital Microfluidics

Samuel R. Little, Ziuwin Leung, Angela B.V. Quach, Alison Hirukawa, Fatemeh Gholizadeh, Mehri Hajiaghayi, Peter J. Darlington and Steve C.C. Shih

Adv Materials Technologies, 2023, 8
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Technologies for chimeric antigen receptor transgene delivery

Yudian Xiao, Bowen Wu, Qiuping Zhou, Fan Wu, Nei Li, Chenqi Xu and Xuexiang Han

Trends in Molecular Medicine, 2025
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Research advances of nanoparticles for CAR-T therapy in solid tumors

Bohan Chen, Liming Gong, Jing Feng, Mingji Jin, Liqing Chen, Zhonggao Gao and Wei Huang

Chinese Chemical Letters, 2024, 35, 109432
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Opportunities and obstacles for the melanoma immunotherapy using T cell and chimeric antigen receptor T (CAR-T) applications: a literature review

Maryam Bahmanyar, Mohammad Kazem Vakil, Ghaidaa Raheem Lateef Al-Awsi, Seyed Amin Kouhpayeh, Hosein Mansoori, Yaser Mansoori, Afsaneh Salahi, Ghasem Nikfar, Alireza Tavassoli, Esmaeil Behmard, Ali Moravej and Abdolmajid Ghasemian

Mol Biol Rep, 2022, 49, 10627
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The Pre-Polarization and Concentration of Cells near Micro-Electrodes Using AC Electric Fields Enhances the Electrical Cell Lysis in a Sessile Drop

Kishor Kaphle and Dharmakeerthi Nawarathna

Biosensors, 2025, 15, 22
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Biomaterials for chimeric antigen receptor T cell engineering

Huanqing Niu, Penghui Zhao and Wujin Sun

Acta Biomaterialia, 2023, 166, 1
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Cancer immunotherapies: advances and bottlenecks

Rui Rui, Liqun Zhou and Shiming He

Front. Immunol., 2023, 14
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Synthetic circRNA therapeutics: innovations, strategies, and future horizons

Jingsheng Cai, Zonghao Qiu, William Chi‐Shing Cho, Zheng Liu, Shaoyi Chen, Haoran Li, Kezhong Chen, Yun Li, Chijian Zuo and Mantang Qiu

MedComm, 2024, 5
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Recent Advances in Microscale Electroporation

Sung-Eun Choi, Harrison Khoo and Soojung Claire Hur

Chem. Rev., 2022, 122, 11247
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