Development of a xanthene-based NIR fluorescent probe for accurate and sensitive detection of γ-glutamyl transpeptidase in cancer diagnosis and treatment

Chia-Kai Lai, Kuppan Magesh, Sivan Velmathi and Shu-Pao Wu

J. Mater. Chem. B, 2025, 13, 201
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Highly emissive dibenzofuranfluorophores with aggregation-induced emission for bioimaging in HeLa cell lines

Nikita Kush Durgi and Prasad Pralhad Pujar

RSC Adv., 2025, 15, 35253
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Debut of enzyme-responsive anionic cyanine for overlap-free NIR-II-to-I dual-channel tumour imaging

Feiyi Chu, Bin Feng, Yiyang Zhou, Min Liu, Hailiang Zhang, Meihui Liu, Qian Chen, Shengwang Zhang, Yeshuo Ma, Jie Dong, Fei Chen and Wenbin Zeng

Chem. Sci., 2025, 16, 4490
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Chemistry of 2-(2′-Aminophenyl)benzothiazole Derivatives: Syntheses, Photophysical Properties and Applications

Ekaterina K. Pylova, Taisiya S. Sukhikh, Alexis Prieto, Florian Jaroschik and Sergey N. Konchenko

Molecules, 2025, 30, 1659
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ESIPT‐based AIE luminogens: Design strategies, applications, and mechanisms

Panwang Zhou and Keli Han

Aggregate, 2022, 3
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Research Advances in Excited State Intramolecular Proton Transfer Fluorescent Probes Based on Combined Fluorescence Mechanism

Xian-Lin LU and Wei HE

Chinese Journal of Analytical Chemistry, 2021, 49, 184
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Constructing a novel fluorescence detection method for γ-glutamyltranspeptidase and application on visualizing liver injury

Kai Wang, Wei Wang, Xu-Yang Chen, Yu-Shun Yang and Hai-Liang Zhu

Biosensors and Bioelectronics, 2023, 219, 114767
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Constructing a Novel Fluorescence Detection Method for Γ-Glutamyltranspeptidase and Application on Visualizing Liver Injury

Kai Wang, Yu-Shun Yang and Hai-Liang Zhu

SSRN Journal, 2022
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Tumour‐targeted fluorescence‐guided surgery in gastrointestinal cancer: A systematic review of preclinical and clinical research

Aaya Darai, Evie H. M. Graus, Femke J. A. van der Stroom, Mark Rijpkema, Alexander Vahrmeijer, Denise E. Hilling, Johannes H. W. De Wilt and Merlijn Hutteman

Clinical & Translational Med, 2026, 16
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In Vivo Imaging of γ-Glutamyl Transferase in Cardiovascular Diseases with a Photoacoustic Probe

Kai Wang, Ying Yue, Xu-Yang Chen, Xiao-Lin Wen, Bing Yang, Shen-Zhen Ren, Yu-Shun Yang and Hao-Xiang Jiang

ACS Sens., 2024, 9, 962
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Monitoring intracellular pH fluctuation with an excited-state intramolecular proton transfer-based ratiometric fluorescent sensor

Bin Feng, Yingli Zhu, Jiaxin Wu, Xueyan Huang, Rong Song, Liu Huang, Xueping Feng and Wenbin Zeng

Chinese Chemical Letters, 2021, 32, 3057
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A ratiometric fluorescent probe for detection of γ-glutamyl transpeptidase in blood serum and living cells

Shuai Wang, Weimin Liu, Xiuli Zheng, Haohui Ren, Jiasheng Wu, Fan Li and Pengfei Wang

Spectrochimica Acta Part A: Molecular and Biomolecular Spectroscopy, 2022, 278, 121325
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Fidelity-oriented fluorescence imaging probes for beta-galactosidase: From accurate diagnosis to precise treatment

Bin Feng, Feiyi Chu, Anyao Bi, Xueyan Huang, Yanpeng Fang, Meihui Liu, Fei Chen, Yanbing Li and Wenbin Zeng

Biotechnology Advances, 2023, 68, 108244
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Debut of a NIR ESIPT-based fluorescent probe with synergistic effects for boosting high-contrast imaging of β-galactosidase in ovarian cancer

Bin Feng, Feiyi Chu, Xueyan Huang, Yanpeng Fang, Min Liu, Meihui Liu, Fei Chen and Wenbin Zeng

Sensors and Actuators B: Chemical, 2023, 396, 134541
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Investigating the efficacy of a photoacoustic probe in liver function assessment for diabetic mellitus

Dake Wen, Ru Yan, Jian He, Ling Gu, Xu-Yang Chen and Kai Wang

Spectrochimica Acta Part A: Molecular and Biomolecular Spectroscopy, 2025, 342, 126490
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Biosensors for the Detection of Enzymes Based on Aggregation-Induced Emission

Fengli Gao, Gang Liu, Mingyi Qiao, Yingying Li and Xinyao Yi

Biosensors, 2022, 12, 953
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Heteroaryl‐Substituted Bis‐Anils: Aggregation‐Induced Emission (AIE) Derivatives with Tunable ESIPT Emission Color and pH Sensitivity

Timothée Stoerkler, Pascal Retailleau, Denis Jacquemin, Gilles Ulrich and Julien Massue

Chemistry A European J, 2023, 29
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Assembly fluorescent probe-based detection of gamma-glutamyl transferase activity in tumor

Weiwang Zheng, Jing Wu, Nannan Song, Baonan Zhang, Chunhui Jin, Weibo Zhao, Kai Wang, Shenghua Wang, Xiaodan Zhu and Cui Sun

Spectrochimica Acta Part A: Molecular and Biomolecular Spectroscopy, 2025, 340, 126381
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Precise probe design based ESIPT coupled AIE mechanism toward endogenous cyanide in food detection and bioimaging

Cuibing Bai, Jie Zhang, Yuxin Qin, Huanan Huang, Zhenni Xia, Qijun Zheng, Hongliang Dai, Pengkai Lu, Hui Miao, Changqing Qu and Rui Qiao

Chemical Engineering Journal, 2022, 443, 136445
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Near-infrared imaging of hepatocellular carcinoma and its medicinal treatment with a γ-glutamyl transpeptidase-monitoring fluorescence probe

Kai Wang, Xu-Yang Chen, Bo Zhang, Ying Yue, Xiao-Lin Wen, Yang Yang, Yu-Shun Yang, Hai-Liang Zhu, Hong-Ji Liu and Ai-Guo Zhang

Biosensors and Bioelectronics, 2023, 241, 115721
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Advances and Perspectives of Responsive Probes for Measuring γ-Glutamyl Transpeptidase

Yiming Zhang, Zexi Zhang, Miaomiao Wu and Run Zhang

ACS Meas. Sci. Au, 2024, 4, 54
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Using Cu2+ to regulate the emission feature of near-infrared fluorescent sensor with AIE: To detect ascorbic acid in food samples and its application in bioimaging

Qian Meng, Junxiong Yao, Mengyu Chen, Yajie Dong, Xinyi Liu, Shuyang Zhao, Rui Qiao, Cuibing Bai, Changqing Qu and Hui Miao

Analytica Chimica Acta, 2023, 1276, 341602
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Efficient red fluorescent OLEDs based on aggregation-induced emission combined with hybridized local and charge transfer state

Yuan Yu, Miao Cang, Wei Cui, Lei Xu, Runze Wang, Mizhen Sun, Huayi Zhou, Wenjun Yang and Shanfeng Xue

Dyes and Pigments, 2021, 184, 108770
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Tetraphenylethene derivatives with AIE-ESIPT characteristics: Synthesis, crystal structures, photophysical properties and application for ClO− detection and pH sensing

Siqin Yi, Hongliang Liu, Xue Li, Zhao Chen, Congbin Fan and Shouzhi Pu

Dyes and Pigments, 2023, 219, 111598
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A simple “spraying” fluorescence‐guided surgery by AIE probes for liver tumor resection through configuration‐induced cross‐identification

Didi Chen, Tian Xiao, Liangjie Wang, Sijie Chen, Chuen Kam, Guoping Zeng, Li Peng, Jinxiang Zhang, Min Li and Yuping Dong

Aggregate, 2024, 5
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Research Progress in Near-Infrared Small-Molecule Fluorescent Probes Responsive to γ-Glutamyl Transferase

Mengyao Luo, Changqing Ye and Hongli Bao

Synthesis, 2026, 58, 845
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Aggregation-induced emission: Application in diagnosis and therapy of hepatocellular carcinoma

Wenjing Xu, Danfeng Jian, Huang Yang, Weili Wang and Yuan Ding

Biosensors and Bioelectronics, 2024, 266, 116722
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Recent advances in the development of fluorescent probes for γ‐glutamyltranspeptidase

Ze-Yang Hu, Xu-Yang Chen, Yu-Shun Yang, Sheng-Jun Wang, Zhi-Gang Hu and Kai Wang

Coordination Chemistry Reviews, 2024, 501, 215562
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γ-Glutamyltranspeptidase (GGT) Sensitive Fluorescence Probes for Cancer Diagnosis; Brief Review

Muhammad Saleem, Muhammad Hanif, Muhammad Rafiq, Hussain Raza, Kim Song Ja and Changrui Lu

J Fluoresc, 2024, 34, 977
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Imaging Investigation of Hepatocellular Carcinoma Progress via Monitoring γ-Glutamyltranspeptidase Level with a Near-Infrared Fluorescence/Photoacoustic Bimodal Probe

Kai Wang, Xu-Yang Chen, Wen-Dong Liu, Ying Yue, Xiao-Lin Wen, Yu-Shun Yang, Ai-Guo Zhang and Hai-Liang Zhu

Anal. Chem., 2023, 95, 14235
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Simple isomeric pyridine-based fluorescence-off probes for in vitro monitoring γ-glutamyltranspeptidase activity: Design, synthesis and application

Chen He, Hua Wang, Li Fu, Qi Wang, Yingfang Zhong, Mimi Zeng, Xiaofeng Lin, Junyun Huang, Jun Xie, Qitong Huang and Min Yang

Dyes and Pigments, 2024, 228, 112252
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A facile AIEgen-based fluorescent probe design strategy and its application in hypochlorite probe construction

Chenggong Xu, Yanmei Zhou, Yali Cui, Xiaoqiang Liu and Xiaojun Peng

Sensors and Actuators B: Chemical, 2020, 314, 128083
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Extensive optical and DFT studies on novel AIE active fluorescent sensor for Colorimetric and fluorometric detection of nitrobenzene in Solid, solution and vapor phase

Aqsa Pervaiz, Sohail Anjum Shahzad, Mohammed A. Assiri, Tayyeba Javid, Hasher Irshad and Khanzadi Omama Khan

Spectrochimica Acta Part A: Molecular and Biomolecular Spectroscopy, 2024, 313, 124121
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AIE luminogens as fluorescent bioprobes

Guangle Niu, Ruoyao Zhang, Xiujuan Shi, Hojeong Park, Sheng Xie, Ryan T.K. Kwok, Jacky W.Y. Lam and Ben Zhong Tang

TrAC Trends in Analytical Chemistry, 2020, 123, 115769
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Highly selective discrimination of cysteine from glutathione and homo-cysteine with a novel AIE-ESIPT fluorescent probe

Bin Feng, Yi Liu, Shuai Huang, Xueyan Huang, Liu Huang, Min Liu, Jiaxin Wu, Tao Du, Shuanglian Wang, Xueping Feng and Wenbin Zeng

Sensors and Actuators B: Chemical, 2020, 325, 128786
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Recent advances in organic fluorescent probes for tumor related enzyme detection

Huiqi Han, Yingfang Zhong, Chen He, Li Fu, Qitong Huang, Ying Kuang, Xiaoqing Yi, Weijia Zeng, Hongfa Zhong and Min Yang

Dyes and Pigments, 2022, 204, 110386
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Synthesis of a polymerizable aggregation-induced emission (AIE) dye with A-D structure based on benzothiadiazole for fluorescent nanoparticles and its application in bioimaging

Zengfang Huang, Chaoyue Zhou, Yang Yu, Siyi Wang, Rao Fu, Xiaobo Liu, Liucheng Mao, Jinying Yuan, Lei Tao and Yen Wei

European Polymer Journal, 2022, 181, 111705
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