One-pot synthesis of efficient multifunctional nitrogen-doped carbon dots with efficient yellow fluorescence emission for detection of hypochlorite and thiosulfate

Yifang Gao, Yang Liu, Huilin Zhang, Wenjing Lu, Yuan Jiao, Shaomin Shuang and Chuan Dong

J. Mater. Chem. B, 2022, 10, 8910
DOI: 10.1039/D2TB01695H

Triphenylphosphonium-based mitochondrial targeting in cancer therapy: mechanisms, progress, and perspectives

Min Yang, Jiaming Ou, Haibo Yan, Yun He, Linling Gan and Shao-Lin Zhang

Chem. Commun., 2025, 61, 18937
DOI: 10.1039/D5CC05709D

Recent advances in small-molecule fluorescent probes with the function of targeting cancer receptors

Xinke Li, Caiyun Liu, Hanchuang Zhu, Kun Wang, Xiaohua Ren, Lixue Ma, Xiaohui Zhang, Mengyuan Liu and Baocun Zhu

Anal. Methods, 2023, 15, 5947
DOI: 10.1039/D3AY01387A

The reduction performance of double bonds regulated by the competition of push–pull electron groups to realize the colorimetric and fluorescence recognition of hypochlorous acid

Yan Shi, Fangjun Huo, Yongbin Zhang and Caixia Yin

Analyst, 2020, 145, 7297
DOI: 10.1039/D0AN01551B

Highly efficient approach for hypochlorous acid sensing in water samples and living cells based on acylhydrazone Schiff base functionalized fluorescent probes

Zheng Yang, Yuanlong He, Xiangrong Liu, Shunsheng Zhao, Zaiwen Yang and Shuilan Yang

New J. Chem., 2017, 41, 12250
DOI: 10.1039/C7NJ01383C

A highly selective fluorescence turn-on detection of ClO−with 1-methyl-1,2-dihydropyridine-2-thione unit modified tetraphenylethylene

Xiaobiao Dong, Guanxin Zhang, Jinbiao Shi, Yuancheng Wang, Ming Wang, Qian Peng and Deqing Zhang

Chem. Commun., 2017, 53, 11654
DOI: 10.1039/C7CC07092F

Si-rhodamine fluorescent probe for monitoring of hypochlorous acid in the brains of mice afflicted with neuroinflammation

Fanghui Liang, Jian Jiang, Xinyue Yang, Guoyang Zhang, Jiaying Zhou, Jiahao Han, Yujie Geng and Zhuo Wang

Chem. Commun., 2023, 59, 1357
DOI: 10.1039/D2CC06475H

A fast response fluorescence probe specific for hypochlorous acid detection and its applications in bioimaging

Hongmin Jia, Shuhe Xia, Huan Feng, Qingtao Meng, Chengchen Duan, Zhiqiang Zhang and Run Zhang

Org. Biomol. Chem., 2018, 16, 2074
DOI: 10.1039/C8OB00036K

A HClO-activated endoplasmic reticulum fluorescent probe for visualization of ferroptosis-mediated acute alcoholic gastric and liver injury

Rui Wang, Sijie Li, Hui Wang, Yongming Yang, Mengjuan Shi, Xue Yu, Peng Lei, Xihua Yang, Shaomin Shuang, Chuan Dong and Li Fan

Chem. Commun., 2026, 62, 6141
DOI: 10.1039/D6CC00671J

A new red fluorescent probe based on rosamine–phenothiazine for the highly selective and rapid detection of hypochlorite and its bioimaging in live cells

Yun Zhao, Yuanyuan Xue, Juanjuan Sun, Hongli Xuan, Yunli Xu, Yapeng Cui and Jinlong Dong

New J. Chem., 2020, 44, 12674
DOI: 10.1039/D0NJ02945A

Lighting up hypochlorous acid through C(sp2)–H hydroxylation with a solvatochromic organoiridium(iii) complex-based probe

Bhaskar Sen, Jogat Gogoi, Kripamoy Aguan and Snehadrinarayan Khatua

Analyst, 2026
DOI: 10.1039/D6AN00002A

Mitochondria and lysosome-targetable fluorescent probes for HOCl: recent advances and perspectives

Mingguang Ren, Kai Zhou, Longwei He and Weiying Lin

J. Mater. Chem. B, 2018, 6, 1716
DOI: 10.1039/C7TB03337K

Donor–acceptor type aggregation-induced emission luminophores based on the 1,1-dicyanomethylene-3-indanone unit for bridge-dependent reversible mechanochromism and light-up biosensing of hypochlorites

Hai-Xia Yu, Junge Zhi, Tianjiao Shen, Weilu Ding, Xiaoling Zhang and Jin-Liang Wang

J. Mater. Chem. C, 2019, 7, 8888
DOI: 10.1039/C9TC01772K

Fluorescent probes for organelle-targeted bioactive species imaging

Peng Gao, Wei Pan, Na Li and Bo Tang

Chem. Sci., 2019, 10, 6035
DOI: 10.1039/C9SC01652J

Fluorescent Wittig reagent as a novel ratiometric probe for the quantification of 5-formyluracil and its application in cell imaging

Qian Zhou, Kun Li, Yan-Hong Liu, Ling-Ling Li, Kang-Kang Yu, Hong Zhang and Xiao-Qi Yu

Chem. Commun., 2018, 54, 13722
DOI: 10.1039/C8CC07541G

A turn-on fluorescent probe based onN-(rhodamine-B)-thiolactam-2-n-butane with ionic liquids for selective and sensitive detection of mustard gas stimulant

Daxue Li, Hailing Xi, Shitong Han and Sanping Zhao

Anal. Methods, 2021, 13, 484
DOI: 10.1039/D0AY02248A

A ratiometric fluorescent probe for detecting hypochlorite in the endoplasmic reticulum

Ji-Ting Hou, Hyeong Seok Kim, Chong Duan, Myung Sun Ji, Shan Wang, Lintao Zeng, Wen Xiu Ren and Jong Seung Kim

Chem. Commun., 2019, 55, 2533
DOI: 10.1039/C9CC00066F

Light emission enhancement by supramolecular complexation of chemiluminescence probes designed for bioimaging

Samer Gnaim, Anna Scomparin, Anat Eldar-Boock, Christoph R. Bauer, Ronit Satchi-Fainaro and Doron Shabat

Chem. Sci., 2019, 10, 2945
DOI: 10.1039/C8SC05174G

Multifunctional gold nanoparticles as smart nanovehicles with enhanced tumour-targeting abilities for intracellular pH mapping and in vivo MR/fluorescence imaging

Kang-Kang Yu, Kun Li, Chun-Yan Lu, Yong-Mei Xie, Yan-Hong Liu, Qian Zhou, Jin-Ku Bao and Xiao-Qi Yu

Nanoscale, 2020, 12, 2002
DOI: 10.1039/C9NR06347A

Ratiometric fluorescent probes for capturing endogenous hypochlorous acid in the lungs of mice

Xinfu Zhang, Weiyu Zhao, Bin Li, Wenqing Li, Chengxiang Zhang, Xucheng Hou, Justin Jiang and Yizhou Dong

Chem. Sci., 2018, 9, 8207
DOI: 10.1039/C8SC03226B

A benzothiazole-based fluorescent probe for hypochlorite – highly sensitive detection and live-cell imaging research

Kelong Fang, Xiaozhen Ma and Yuliang Jiang

Anal. Methods, 2026, 18, 907
DOI: 10.1039/D5AY01966D

Enhanced fluorescence sensing of hypochlorous acid using serum albumin as a signal amplifier

Peng Zhang, Qian Zhang, Shasha Li, Wenhui Chen, Xinjie Guo and Caifeng Ding

J. Mater. Chem. B, 2019, 7, 1238
DOI: 10.1039/C8TB03023E

An ESIPT-based colorimetric and fluorescent probe with large Stokes shift for the sensitive detection of hypochlorous acid and its bioimaging in cells

Haixian Ren, Fangjun Huo and Caixia Yin

New J. Chem., 2021, 45, 4724
DOI: 10.1039/D0NJ05807F

A naphthalimide based fast and selective fluorescent probe for hypochlorous acid/hypochlorite and its application for bioimaging

Xin Lv, Xia Yuan, Yue Wang and Wei Guo

New J. Chem., 2018, 42, 15105
DOI: 10.1039/C8NJ03208D

Squaraine-based AIEgens for reversible mechanochromism, sensitive and selective hypochlorite detection and photostable far-red fluorescence cell imaging

Weiguo Qiao, Peigen Yao, Yu Chen, Qi Xiao, Lianbin Zhang and Zhong’an Li

Mater. Chem. Front., 2020, 4, 2688
DOI: 10.1039/D0QM00357C

A novel highly specific and ultrasensitive fluorescent probe for monitoring hypochlorous acid and its application in live cells

Xinyuan Li, Liu Wu, Ziyang Zhao, Caiyun Liu and Baocun Zhu

RSC Adv., 2019, 9, 4659
DOI: 10.1039/C8RA09551E

A dual-mode probe based on AIE and TICT effects for the detection of the hypochlorite anion and its bioimaging in living cells

Yang Zhou, Hai Xu, Qing-Xiu Li, Zong-Rui Hou, Ya-Wen Wang and Yu Peng

Org. Biomol. Chem., 2023, 21, 1270
DOI: 10.1039/D2OB02138B

A novel porphyrin-based near-infrared fluorescent probe for hypochlorite detection and its application in vitro and in vivo

Xiaoyi Wang, Jie Min, Weijie Wang, Yan Wang, Gui Yin and Ruiyong Wang

Analyst, 2018, 143, 2641
DOI: 10.1039/C8AN00586A

Design and Synthesis of Galactose-Biotin Lipid Materials for Liposomes to Promote the Hepatoma Cell–Targeting Effect

Ruihua Ding, Zhenjie Li, Jianyi Wang, Xueyan Zhu, Zhuang Zhao and Mian Wang

Journal of Pharmaceutical Sciences, 2019, 108, 3074
DOI: 10.1016/j.xphs.2019.04.007

Recent advances in small-molecule fluorescent probes for diagnosis of cancer cells/tissues

Kun Wang, Caiyun Liu, Hanchuang Zhu, Yan Zhang, Meijun Su, Xin Wang, Mengyuan Liu, Xiaodi Rong and Baocun Zhu

Coordination Chemistry Reviews, 2023, 477, 214946
DOI: 10.1016/j.ccr.2022.214946

A highly sensitive turn-on fluorescent probe for real-time detecting hypochlorite and its application in living cells

Yilin Zhu, Kangnan Wang, Xiangwen Wu, Yanan Sun, Xiangshuo Gong, Duxia Cao, Ruifang Guan and Zhiqiang Liu

Talanta, 2020, 209, 120548
DOI: 10.1016/j.talanta.2019.120548

Luminescent metal organic frameworks with recognition sites for detection of hypochlorite through energy transfer

Lan Guo, Yuan Liu, Fengli Qu, Zhe Liu, Rongmei Kong, Guang Chen, Wenjing Fan and Lian Xia

Microchim Acta, 2019, 186
DOI: 10.1007/s00604-019-3806-x

Super stable CsPbBr3@SiO2 tumor imaging reagent by stress-response encapsulation

Wentao Song, Yiming Wang, Bing Wang, Yingfang Yao, Wenguang Wang, Jinhui Wu, Qing Shen, Wenjun Luo and Zhigang Zou

Nano Res., 2020, 13, 795
DOI: 10.1007/s12274-020-2697-9

Ratiometric fluorescent probe for the detection of HOCl in lysosomes based on FRET strategy

Shi-Li Shen, Xiao-Qing Huang, Yao-Yao Zhang, Yan Zhu, Chao Hou, Yan-Qing Ge and Xiao-Qun Cao

Sensors and Actuators B: Chemical, 2018, 263, 252
DOI: 10.1016/j.snb.2018.02.121

Turn-on Fluorescent Probe for Exogenous and Endogenous Imaging of Hypochlorous Acid in Living Cells and Quantitative Application in Flow Cytometry

Zixuan Zhan, Rui Liu, Li Chai, Qiuyan Li, Kexin Zhang and Yi Lv

Anal. Chem., 2017, 89, 9544
DOI: 10.1021/acs.analchem.7b02613

Design, Synthesis, and Applications of a Novel Hypochlorite Probe Based on Pyridinium Salt

Y. Xu, L. Zhao, Y.-H. Zhao and Z. Tang

Russ J Gen Chem, 2023, 93, 2404
DOI: 10.1134/S1070363223090219

Recent advances in functional activatable probes for oncological surgery: Illuminating precision or hindering clinical translation?

Jialiang Lu, Weihao Zhuang, Xiaowu Dong and Haiyan Yang

European Journal of Medicinal Chemistry, 2025, 297, 117930
DOI: 10.1016/j.ejmech.2025.117930

Ultrasensitive two-photon probes for rapid detection of β-galactosidase during fruit softening and cellular senescence

Yi-Min Shan, Kang-Kang Yu, Fan-Yuan Yu, Yan-Hong Liu, Xiao-Qi Yu and Kun Li

Food Chemistry, 2024, 431, 137117
DOI: 10.1016/j.foodchem.2023.137117

Novel diaminomaleonitrile-based fluorescent probe for ratiometric detection and bioimaging of hypochlorite

Yuliang Jiang, Shishan Wu, Can Jin, Bingxiang Wang and Jian Shen

Sensors and Actuators B: Chemical, 2018, 265, 365
DOI: 10.1016/j.snb.2018.01.202

HClO/ClO–-Indicative Interpenetrating Polymer Network Hydrogels as Intelligent Bioactive Materials for Wound Healing

Nan Wang, Kang-Kang Yu, Yi-Min Shan, Kun Li, Jun Tian, Xiao-Qi Yu and Xi Wei

ACS Appl. Bio Mater., 2020, 3, 37
DOI: 10.1021/acsabm.9b00806

Development of a Concise Rhodamine-Formylhydrazine Type Fluorescent Probe for Highly Specific and Ultrasensitive Tracing of Basal HOCl in Live Cells and Zebrafish

Caiyun Liu, Zilu Li, Chen Yu, Yanan Chen, Dongmei Liu, Zihan Zhuang, Pan Jia, Hanchuang Zhu, Xue Zhang, Yamin Yu, Baocun Zhu and Wenlong Sheng

ACS Sens., 2019, 4, 2156
DOI: 10.1021/acssensors.9b01001

A highly specific and ultrasensitive near-infrared fluorescent probe for imaging basal hypochlorite in the mitochondria of living cells

Baocun Zhu, Liu Wu, Meng Zhang, Yawei Wang, Caiyun Liu, Zuokai Wang, Qingxia Duan and Pan Jia

Biosensors and Bioelectronics, 2018, 107, 218
DOI: 10.1016/j.bios.2018.02.023

A new coumarin-based “turn-on” fluorescence probe with high sensitivity and specificity for detecting hypochlorite ion

Lei Du, Yiqiu Xie, Hui Qian, Wenqi Zhou, Qingying Yang, Xinyu Sun and Limin Wang

Dyes and Pigments, 2022, 200, 110137
DOI: 10.1016/j.dyepig.2022.110137

Nanomedicines for Subcellular Targeting: The Mitochondrial Perspective

Olakunle Oladimeji, Jude Akinyelu and Moganavelli Singh

CMC, 2020, 27, 5480
DOI: 10.2174/0929867326666191125092111

Recent progress and outlooks in rhodamine-based fluorescent probes for detection and imaging of reactive oxygen, nitrogen, and sulfur species

Ping Yang, A-Ling Tang, Shuai Tan, Guang-Ye Wang, Hou-Yun Huang, Wei Niu, Shi-Tao Liu, Mei-Hong Ge, Lin-Lin Yang, Feng Gao, Xiang Zhou, Li-Wei Liu and Song Yang

Talanta, 2024, 274, 126004
DOI: 10.1016/j.talanta.2024.126004

Ex Tenebris Lux: Illuminating Reactive Oxygen and Nitrogen Species with Small Molecule Probes

Maidileyvis C. Cabello, Gen Chen, Michael J. Melville, Rokia Osman, G. Dinesh Kumar, Dylan W. Domaille and Alexander R. Lippert

Chem. Rev., 2024, 124, 9225
DOI: 10.1021/acs.chemrev.3c00892

A mitochondria-targeted NIR fluorescence/photoacoustic dual-modality probe for highly sensitive and selective imaging of HClO in vivo

Yonghe Liao, Tingzhuang Yi, Kangyi Tan, Xiaoyan Su, Shuixiu Chen, Mingyue Lu, Yanchun Yang, Xianxian Huang, Yiheng Zhao, Hong Huang, Neng Jiang, Zhiming Yan and Changhong Wei

Spectrochimica Acta Part A: Molecular and Biomolecular Spectroscopy, 2025, 330, 125680
DOI: 10.1016/j.saa.2024.125680

Sensors, Imaging Agents, and Theranostics to Help Understand and Treat Reactive Oxygen Species Related Diseases

Kai‐Cheng Yan, Adam C. Sedgwick, Yi Zang, Guo‐Rong Chen, Xiao‐Peng He, Jia Li, Juyoung Yoon and Tony D. James

Small Methods, 2019, 3
DOI: 10.1002/smtd.201900013

Photocontrollable Fluorogenic Probe for Visualizing Near‐Membrane Hypochlorite in Live Cells

Pingping Peng, Hao Li, Lei Bai, Liulin Wang, Buxiang Chen, Changmin Yu, Chengwu Zhang, Jingyan Ge, Lin Li and Wei Huang

ChemistrySelect, 2018, 3, 5981
DOI: 10.1002/slct.201800777

Two-photon ratiometric fluorescent probe for imaging of hypochlorous acid in acute lung injury and its remediation effect

Zixuan Zhan, Li Chai, Qian Lei, Xinglong Zhou, Yuxi Wang, Hui Deng, Yi Lv and Weimin Li

Analytica Chimica Acta, 2021, 1187, 339159
DOI: 10.1016/j.aca.2021.339159

Near-Infrared Fluorescent Turn-On Probe for Selective Detection of Hypochlorite in Aqueous Medium and Live Cell Imaging

Anwesha Maiti, Saikat Kumar Manna, Satyajit Halder, Rajdeep Ganguly, Anirban Karak, Pintu Ghosh, Kuladip Jana and Ajit Kumar Mahapatra

Chem. Res. Toxicol., 2024, 37, 1682
DOI: 10.1021/acs.chemrestox.4c00222

Design of innovative and low-cost dopamine-biotin conjugate sensor for the efficient detection of protein and cancer cells

Monica Notarbartolo, Maria Laura Alfieri, Roberto Avolio, Vincent Ball, Maria Emanuela Errico, Marina Massaro, Roberta Puglisi, Rita Sànchez-Espejo, César Viseras and Serena Riela

Journal of Colloid and Interface Science, 2025, 678, 766
DOI: 10.1016/j.jcis.2024.09.145

“ESIPT-AIE” based sequential fluorescence ‘on-off’ marker for endogenous detection of hypochlorite and cobalt (II)

Sanay Naha and Sivan Velmathi

Microchemical Journal, 2020, 153, 104499
DOI: 10.1016/j.microc.2019.104499

A ratiometric fluorescence probe based on a novel recognition mechanism for monitoring endogenous hypochlorite in living cells

Ye-Hao Yan, Han-Lin Ma, Jun-Ying Miao, Bao-Xiang Zhao and Zhao-Min Lin

Analytica Chimica Acta, 2019, 1064, 87
DOI: 10.1016/j.aca.2019.03.004

Rational design of a highly efficient two-photon fluorescent probe for tracking intracellular basal hypochlorous acid and its applications in identifying tumor cells and tissues

Caiyun Liu, Pan Jia, Liu Wu, Zilu Li, Hanchuang Zhu, Zuokai Wang, Shuo Deng, Wei Shu, Xue Zhang, Yamin Yu and Baocun Zhu

Sensors and Actuators B: Chemical, 2019, 297, 126731
DOI: 10.1016/j.snb.2019.126731

A BODIPY‐Diaminomaleonitrile Based Water‐Soluble Fluorescent Probe for Selective “Off‐On” Detection of Hypochlorite**

Junqiang Leng, Wen Nie, Linying Yuan, Shuang Liu, Tianxin Liu, Jianbo Cheng and Zhenbo Liu

ChemistrySelect, 2022, 7
DOI: 10.1002/slct.202200378

Small-Molecule Fluorescent Probes for Imaging and Detection of Reactive Oxygen, Nitrogen, and Sulfur Species in Biological Systems

Xiaoyun Jiao, Yong Li, Jinye Niu, Xilei Xie, Xu Wang and Bo Tang

Anal. Chem., 2018, 90, 533
DOI: 10.1021/acs.analchem.7b04234

Preparation of an Efficient Ratiometric Fluorescent Nanoprobe (m-CDs@[Ru(bpy)3]2+) for Visual and Specific Detection of Hypochlorite on Site and in Living Cells

Yuanjin Zhan, Fang Luo, Longhua Guo, Bin Qiu, Yuhong Lin, Juan Li, Guonan Chen and Zhenyu Lin

ACS Sens., 2017, 2, 1684
DOI: 10.1021/acssensors.7b00601

Rapid and selective visualization of mitochondrial hypochlorite by a red region water-soluble fluorescence probe

Tian-Ran Wang, Xiao-Fan Zhang, Xiao-Qing Huang, Xiao-Qun Cao and Shi-Li Shen

Spectrochimica Acta Part A: Molecular and Biomolecular Spectroscopy, 2021, 247, 119115
DOI: 10.1016/j.saa.2020.119115

A novel mitochondria-targetable probe for imaging endogenous deoxyribonucleic acid in biological systems

Jie Niu, Yong Liu, Weishan Wang and Weiying Lin

Journal of Photochemistry and Photobiology A: Chemistry, 2019, 378, 57
DOI: 10.1016/j.jphotochem.2019.04.008

Two-photon AIE based fluorescent probe with large stokes shift for selective and sensitive detection and visualization of hypochlorite

Qian Zhang, Peng Zhang, Yan Gong and Caifeng Ding

Sensors and Actuators B: Chemical, 2019, 278, 73
DOI: 10.1016/j.snb.2018.09.057

Mitochondrial-targeted near-infrared “dual mode” fluorescent dyes with large Stokes shift for detection of hypochlorous acid and its bioimaging in cell and mice

Yongfei Huang, Yongbin Zhang, Fangjun Huo, Yaoming Liu and Caixia Yin

Dyes and Pigments, 2020, 179, 108387
DOI: 10.1016/j.dyepig.2020.108387

Enhancing Dye‐Triplet‐Sensitized Upconversion Emission Through the Heavy‐Atom Effect in CsLu2F7:Yb/Er Nanoprobes

Peng Zhang, Jianxi Ke, Datao Tu, Jiayao Li, Yifan Pei, Le Wang, Xiaoying Shang, Tianyong Guan, Shan Lu, Zhuo Chen and Xueyuan Chen

Angew Chem Int Ed, 2022, 61
DOI: 10.1002/anie.202112125

A near-infrared fluorescent probe based on photostable Si-rhodamine for imaging hypochlorous acid during lysosome-involved inflammatory response

Guo-Jiang Mao, Zhen-Zhen Liang, Jingjing Bi, Hua Zhang, Hong-Min Meng, Li Su, Yi-Jun Gong, Suling Feng and Guisheng Zhang

Analytica Chimica Acta, 2019, 1048, 143
DOI: 10.1016/j.aca.2018.10.014

Smart Stimuli-Responsive and Mitochondria Targeting Delivery in Cancer Therapy

Yongjia Huang, Tingting Wang, Qunyou Tan, Dan He, Mingjun Wu, Jingchuan Fan, Jie Yang, Cailing Zhong, Kailing Li and Jingqing Zhang

IJN, 2021, Volume 16, 4117
DOI: 10.2147/IJN.S315368

A mitochondria-targeted ratiometric fluorescence sensor for the detection of hypochlorite in living cells

Wei Wang, Jun-Ya Ning, Jin-Ting Liu, Jun-Ying Miao and Bao-Xiang Zhao

Dyes and Pigments, 2019, 171, 107708
DOI: 10.1016/j.dyepig.2019.107708

A rhodamine B-based probe for the detection of HOCl in lysosomes

Shi-Li Shen, Xiao-Qing Huang, Hong-Li Jiang, Xiao-Hui Lin and Xiao-Qun Cao

Analytica Chimica Acta, 2019, 1046, 185
DOI: 10.1016/j.aca.2018.09.054

A fast-response, highly specific fluorescent probe for the detection of picomolar hypochlorous acid and its bioimaging applications

Baocun Zhu, Liu Wu, Meng Zhang, Yawei Wang, Ziyang Zhao, Zuokai Wang, Qingxia Duan, Pan Jia and Caiyun Liu

Sensors and Actuators B: Chemical, 2018, 263, 103
DOI: 10.1016/j.snb.2018.02.083

Mitochondria-targetable small molecule fluorescent probes for the detection of cancer-associated biomarkers: A review

Xue Yu, Yunong Huang, Yunqi Tao, Li Fan and Yuewei Zhang

Analytica Chimica Acta, 2024, 1289, 342060
DOI: 10.1016/j.aca.2023.342060

Recent advances in mitochondria- and lysosomes-targeted small-molecule two-photon fluorescent probes

Peng Ning, Wenjuan Wang, Man Chen, Yan Feng and Xiangming Meng

Chinese Chemical Letters, 2017, 28, 1943
DOI: 10.1016/j.cclet.2017.09.026

A reversible fluorescent probe for Zn2+ and ATP in living cells and in vivo

Xilang Jin, Xianglong Wu, Bo Wang, Pu Xie, Yaolong He, Hongwei Zhou, Bo Yan, Jingjing Yang, Weixing Chen and Xianghan Zhang

Sensors and Actuators B: Chemical, 2018, 261, 127
DOI: 10.1016/j.snb.2018.01.116

Carbon dots for real-time colorimetric/fluorescent dual-mode sensing ClO−/GSH

Huiqing Li, Zhenni Wei, Xianwei Zuo, Hongli Chen, Cuiling Ren, Yalei Dong and Xingguo Chen

Dyes and Pigments, 2022, 206, 110614
DOI: 10.1016/j.dyepig.2022.110614

Small-Molecule Fluorescent Probes for Detecting Several Abnormally Expressed Substances in Tumors

Leilei Yao, Caixia Yin and Fangjun Huo

Micromachines, 2022, 13, 1328
DOI: 10.3390/mi13081328

Mitochondria-Targeted New Blue Light-Emitting Fluorescent Molecular Probe

Saswat Mohapatra, Gaurav Das, Chirantan Kar, Masashi Nitani, Yutaka Ie, Yoshio Aso and Surajit Ghosh

ACS Omega, 2019, 4, 9361
DOI: 10.1021/acsomega.8b03331

The role of nanomaterials on the cancer cells sensing based on folate receptor: Analytical approach

Jafar Soleymani, Mohammad Hasanzadeh, Nasrin shadjou, Mohammad Hossein Somi and Abolghasem Jouyban

TrAC Trends in Analytical Chemistry, 2020, 125, 115834
DOI: 10.1016/j.trac.2020.115834

A lysosome-targetable fluorescent probe based on HClO-mediated cyclization reaction for imaging of hypochlorous acid

Qian-Qian Wang, Ying-Ying Wang, Yao Li, Shu-Yu Zhang, Xin-Yu Guo, Wen-Ke Zha, Wen-Jun Li and Guo-Jiang Mao

ANAL. SCI., 2022, 38, 175
DOI: 10.2116/analsci.21P264

A simple rhodanine-based probe for the fluorescent detection of hypochlorite and its imaging applications in living cells, plants and zebrafish

Kun-Sheng Jin, Jin-Long Yan, Wei-Na Wu, Xiao-Lei Zhao, Yuan Wang, Yun-Chang Fan, Xiao-Xia Li and Zhi-Hong Xu

Journal of Molecular Structure, 2024, 1295, 136697
DOI: 10.1016/j.molstruc.2023.136697

Highly Selective Detection of Hypochlorous Acid by a Bis-heteroleptic Ru(II) Complex of Pyridyl-1,2,3-triazole Ligand via C(sp2)–H Hydroxylation

Bhaskar Sen, Sanjoy Kumar Sheet, Sumit Kumar Patra, Debaprasad Koner, Nirmalendu Saha and Snehadrinarayan Khatua

Inorg. Chem., 2019, 58, 9982
DOI: 10.1021/acs.inorgchem.9b01125

Combining Wittig Olefination with Photoassisted Domino Reaction To Distinguish 5-Formylcytosine from 5-Formyluracil

Qian Zhou, Kun Li, Ling-Ling Li, Kang-Kang Yu, Hong Zhang, Lei Shi, Hao Chen and Xiao-Qi Yu

Anal. Chem., 2019, 91, 9366
DOI: 10.1021/acs.analchem.9b02499

Metal free bioimaging reagent for intracellular citrate in prostate cancer cells using aryl boronate derivative

Kanagaraj Rajalakshmi, Yun-Sik Nam, Muthusamy Selvaraj, Yeonhee Lee and Kang-Bong Lee

Sensors and Actuators B: Chemical, 2018, 259, 90
DOI: 10.1016/j.snb.2017.12.047

Visualization of the elevated levels of hypochlorous acid in Alzheimer's disease with a ruthenium(II) complex-based luminescence probe

Chaolong Liu, Zhipeng Li, Hao Zhang, Hongli Yu, Jianqin Yan, Dengshuai Wei, Zhenhua Song, Jie Cao and Yong Sun

Analytica Chimica Acta, 2023, 1279, 341779
DOI: 10.1016/j.aca.2023.341779

An endoplasmic reticulum-targeted near-infrared probe for monitoring HClO fluctuation in diabetic mice and human blood

Songjiao Li, Ke Yang, Ying Liu, Peipei Wang, Dan Cheng and Longwei He

Sensors and Actuators B: Chemical, 2023, 379, 133253
DOI: 10.1016/j.snb.2022.133253

Development of iridium(III) phosphorescent probe for hypochlorous acid detection in macrophages cells and cancer cells co-culture system and application in inflamed mouse model

Zixuan Zhan, Kexin Zhang, Lichun Zhang, Qiuyan Li and Yi Lv

Sensors and Actuators B: Chemical, 2020, 303, 127016
DOI: 10.1016/j.snb.2019.127016

Phosphorescent iridium(III) complexes as lifetime-based biological sensors for photoluminescence lifetime imaging microscopy

Jie Zhou, Jinlu Li, Kenneth Yin Zhang, Shujuan Liu and Qiang Zhao

Coordination Chemistry Reviews, 2022, 453, 214334
DOI: 10.1016/j.ccr.2021.214334

A tumor-targeting two-photon fluorescent probe with a far-red to NIR emission for imaging basal hypochlorite in cancer cells and tumor

Guo-Jiang Mao, Shu-Yu Zhang, Tian-Tian Yang, Baosong Zhu, Xue-Yu Sun, Qian-Qian Wang and Guisheng Zhang

Talanta, 2024, 277, 126436
DOI: 10.1016/j.talanta.2024.126436

Detecting and bioimaging of hypochlorite by a conjugated fluorescent chemosensor based on thioamide

Ahran Kim, Minji Lee, Hangyul Lee, Haeri So, Soomin Jeong, Ki-Tae Kim and Cheal Kim

Journal of Photochemistry and Photobiology A: Chemistry, 2021, 421, 113531
DOI: 10.1016/j.jphotochem.2021.113531

Development of Asialoglycoprotein-Mediated Hepatocyte-Targeting Antitumor Prodrugs Triggered by Glutathione

Mian Wang, Zhenjie Li, Feiyang Liu, Qingyuan Yi, Chunxiao Pu, Yajie Li, Tingrong Luo, Jian Liang and Jianyi Wang

J. Med. Chem., 2021, 64, 14793
DOI: 10.1021/acs.jmedchem.1c01365

A Mitochondria-Targeted Fluorescence/Photoacoustic Dual-Modality imaging probe for Hypochlorous Acid-Related inflammatory Responses in vivo

Yonghe Liao, Tingzhuang Yi, Xiaoyan Su, Shuixiu Chen, Mingyue Lu, Xianxian Huang, Yanchun Yang, Xiangqing Qin, Chunli Tang, Yiheng Zhao, Hong Huang, Junjie Tan, Zhiming Yan and Neng Jiang

Journal of Photochemistry and Photobiology A: Chemistry, 2025, 462, 116232
DOI: 10.1016/j.jphotochem.2024.116232

Recent advances in reactive small-molecule fluorescent probes for food safety

Nan Wang, Lina Zhang, Jun Li, Qian Zhou, Hui Yang, Yimin Shan, Yuxiang Chen, Kun Li and Xiaoqi Yu

Coordination Chemistry Reviews, 2025, 530, 216480
DOI: 10.1016/j.ccr.2025.216480

Dual-functional probe based on rhodamine for sequential Cu2+ and ATP detection in vivo

Xilang Jin, Jingkai Gao, Pu Xie, Mengchen Yu, Ting Wang, Hongwei Zhou, Aijie Ma, Qian Wang, Xin Leng and Xianghan Zhang

Spectrochimica Acta Part A: Molecular and Biomolecular Spectroscopy, 2018, 204, 657
DOI: 10.1016/j.saa.2018.06.094

Fluorescence enhancement of rhodamine B and fluorescein immobilized on optimized ZrO2 nano-porous films

Miao Zhu, Xixin Wang, Dongxin Liu, Zekun Yin, Fenglin Li and Jianling Zhao

Journal of Physics and Chemistry of Solids, 2021, 157, 110198
DOI: 10.1016/j.jpcs.2021.110198

Antiviral drug discovery and development: challenges and future directions

Shaoqing Du, Xueping Hu, Ping Li, Shujing Xu, Meehyein Kim, Xinyong Liu and Peng Zhan

Sig Transduct Target Ther, 2026, 11
DOI: 10.1038/s41392-025-02539-7

The development of a biotin-guided and mitochondria-targeting fluorescent probe for detecting SO2 precisely in cancer cells

Yunyan Zhang, Xiuqi Kong, Min Li, Yaguang Yin and Weiying Lin

Talanta, 2021, 225, 121992
DOI: 10.1016/j.talanta.2020.121992

Dual-Emissive Metal–Organic Framework as a Fluorescent “Switch” for Ratiometric Sensing of Hypochlorite and Ascorbic Acid

Yong-Nian Zeng, He-Qi Zheng, Jia-Fang Gu, Gao-Juan Cao, Wan-E Zhuang, Jian-Di Lin, Rong Cao and Zu-Jin Lin

Inorg. Chem., 2019, 58, 13360
DOI: 10.1021/acs.inorgchem.9b02251

Mitochondria-targeting drug conjugates for cytotoxic, anti-oxidizing and sensing purposes: current strategies and future perspectives

Gantumur Battogtokh, Yeon Su Choi, Dong Seop Kang, Sang Jun Park, Min Suk Shim, Kang Moo Huh, Yong-Yeon Cho, Joo Young Lee, Hye Suk Lee and Han Chang Kang

Acta Pharmaceutica Sinica B, 2018, 8, 862
DOI: 10.1016/j.apsb.2018.05.006

Imaging of Hypochlorous Acid by Fluorescence and Applications in Biological Systems

Tesla Yudhistira, Sandip V. Mulay, Youngsam Kim, Mahesh B. Halle and David G. Churchill

Chemistry An Asian Journal, 2019, 14, 3048
DOI: 10.1002/asia.201900672

Enhancing Dye‐Triplet‐Sensitized Upconversion Emission Through the Heavy‐Atom Effect in CsLu2F7:Yb/Er Nanoprobes

Peng Zhang, Jianxi Ke, Datao Tu, Jiayao Li, Yifan Pei, Le Wang, Xiaoying Shang, Tianyong Guan, Shan Lu, Zhuo Chen and Xueyuan Chen

Angewandte Chemie, 2022, 134
DOI: 10.1002/ange.202112125

Specific detection of hypochlorite: a cyanine based turn-on fluorescent sensor

Soham Samanta, Senjuti Halder, Utsab Manna and Gopal Das

J Chem Sci, 2019, 131
DOI: 10.1007/s12039-019-1612-y

Development of carbazole-based fluorescent probe for highly sensitive application in fluoride ion detection

Dan Li, San Tu, Yi Le, Yue Zhou, Lan Yang, Yuyu Ding, Lei Huang and Li Liu

Spectrochimica Acta Part A: Molecular and Biomolecular Spectroscopy, 2023, 285, 121816
DOI: 10.1016/j.saa.2022.121816

Highly sensitive and selective “off-on” fluorescent sensing platform for ClO− in water based on silicon quantum dots coupled with nanosilver

Lirong Liu, Gangbing Zhu, Wei Zeng, Baohe Lv and Yinhui Yi

Anal Bioanal Chem, 2019, 411, 1561
DOI: 10.1007/s00216-019-01597-5

The water-soluble bicyclic 2-pyridone-based fluorescent probe for fast and selective detection of hypochlorite

Qian Zhou, Shanqiang Wang, Xiaoyun Ran, Linzhi Shen, Xiaolin Luo, Gui Wang, Hui Yang, Zhouyu Wang and Xiaoqi Yu

Chinese Chemical Letters, 2023, 34, 107922
DOI: 10.1016/j.cclet.2022.107922

Rapid and visual detection for hypochlorite of an AIE enhanced fluorescence probe

Huan‐ren Cheng, Yan Ji, Fei Liu and Xiao‐ju Lu

Luminescence, 2019, 34, 903
DOI: 10.1002/bio.3689

The near-infrared fluorescent probes based on phenoxazine for the rapid detection of hypochlorous acid

Wubin Zheng, Jiajia Yang, Yang Shen, Yusi Yao, Guanglei Lv, Shiyou Hao and Chunxia Li

Dyes and Pigments, 2020, 179, 108404
DOI: 10.1016/j.dyepig.2020.108404

A mitochondria-targetable two-photon fluorescent probe with a far-red to near-infrared emission for sensing hypochlorite in biosystems

Guo-Jiang Mao, Guang-Qi Gao, Zhen-Zhen Liang, Ying-Ying Wang, Li Su, Zhuo-Xi Wang, Hua Zhang, Qiu-Juan Ma and Guisheng Zhang

Analytica Chimica Acta, 2019, 1081, 184
DOI: 10.1016/j.aca.2019.07.040

Recent progress in developing fluorescent probes for imaging cell metabolites

Shanni Hong, Gregory T Pawel, Renjun Pei and Yi Lu

Biomed. Mater., 2021, 16, 044108
DOI: 10.1088/1748-605X/abfd11

Malononitrile as the ‘double-edged sword’ of passivation-activation regulating two ICT to highly sensitive and accurate ratiometric fluorescent detection for hypochlorous acid in biological system

Yan Shi, Fangjun Huo and Caixia Yin

Sensors and Actuators B: Chemical, 2020, 325, 128793
DOI: 10.1016/j.snb.2020.128793

A ROS-responsive hydrogel incorporated with dental follicle stem cell-derived small extracellular vesicles promotes dental pulp repair by ameliorating oxidative stress

Mengjie Li, Jun Tian, Kangkang Yu, He Liu, Xiaoqi Yu, Nan Wang, Qimei Gong, Kun Li, Ya Shen and Xi Wei

Bioactive Materials, 2024, 36, 524
DOI: 10.1016/j.bioactmat.2024.06.036

An AIE fluorescent probe with a naphthalimide derivative and its application for detection of hypochlorite and imaging inside living cells

Mengru Li, Fangkai Du, Pei Xue, Xuecai Tan, Shaogang Liu, Yan Zhou, Jian Chen and Lijuan Bai

Spectrochimica Acta Part A: Molecular and Biomolecular Spectroscopy, 2020, 227, 117760
DOI: 10.1016/j.saa.2019.117760

Fast‐Response Fluorogenic Probe for Visualizing Hypochlorite in Living Cells and in Zebrafish

Yang Ding, Chenchen Xu, Zheng Li, Wenjing Qin, Xisi Han, Xu Han, Chengwu Zhang, Changmin Yu, Xuchun Wang, Lin Li and Wei Huang

ChemBioChem, 2019, 20, 831
DOI: 10.1002/cbic.201800659

A new-type HOCl-activatable fluorescent probe and its applications in water environment and biosystems

Kun Wang, Yilin Liu, Caiyun Liu, Hanchuang Zhu, Xiwei Li, Miaohui Yu, Lunying Liu, Guoqing Sang, Wenlong Sheng and Baocun Zhu

Science of The Total Environment, 2022, 839, 156164
DOI: 10.1016/j.scitotenv.2022.156164

Rational construction of deep-red fluorescent probe for rapid detection of HClO and its application in bioimaging and paper-based sensing

Xingliang Fang, Xilang Jin, Xuehao Ma, Li Guan, Weixing Chen and Mengyao She

Anal Bioanal Chem, 2022, 414, 5887
DOI: 10.1007/s00216-022-04154-9

Recent advances of luminescent sensors for iron and copper: Platforms, mechanisms, and bio-applications

Zhangping Li, Ji-Ting Hou, Shan Wang, Lei Zhu, Xiaojun He and Jianliang Shen

Coordination Chemistry Reviews, 2022, 469, 214695
DOI: 10.1016/j.ccr.2022.214695

Dual-responsive fluorescent probe for hypochlorite via pH-modulated, ring-opening reactions of a coumarin-fused rhodol derivative

Jing-Hui Zhu and Keith Man-Chung Wong

Sensors and Actuators B: Chemical, 2018, 267, 208
DOI: 10.1016/j.snb.2018.03.147

Bioanalytical methods for hypochlorous acid detection: Recent advances and challenges

Run Zhang, Bo Song and Jingli Yuan

TrAC Trends in Analytical Chemistry, 2018, 99, 1
DOI: 10.1016/j.trac.2017.11.015

Rapid detection of hypochlorite by a coumarin-based hydrazide in aqueous solution and its application in live-cell imaging

Lei Wang, Wenxuan Li, Wenjing Zhi, Dandan Ye, Wenli Zhang and Liang Ni

Sensors and Actuators B: Chemical, 2018, 255, 1112
DOI: 10.1016/j.snb.2017.08.039

A ratiometric fluorescent probe with an extremely large emission shift for detecting ClO− and its application in test strips and cell imaging

Xiaohang Xu, Haichang Ding, Qian Zhang, Gang Liu and Shouzhi Pu

Dyes and Pigments, 2022, 207, 110776
DOI: 10.1016/j.dyepig.2022.110776

A novel highly sensitive and near-infrared fluorescent probe for detecting hypochlorite and its application in actual water sample and bioimaging

Lanlan Xu, Minxing Wu, Lihe Zhao, Hao Han, Siqi Zhang, Pinyi Ma, Ying Sun, Xinghua Wang and Daqian Song

Talanta, 2020, 215, 120892
DOI: 10.1016/j.talanta.2020.120892

A pyridine-Si-rhodamine-based near-infrared fluorescent probe for visualizing reactive oxygen species in living cells

Zhengbing Zhou, Xiao Yuan, Da Long, Manhua Liu, Kun Li and Yongmei Xie

Spectrochimica Acta Part A: Molecular and Biomolecular Spectroscopy, 2021, 246, 118927
DOI: 10.1016/j.saa.2020.118927

A fluorescent probe for copper and hypochlorite based on rhodamine hydrazide framework

Jung Won Yoon, Min Jung Chang, Seungwoo Hong and Min Hee Lee

Tetrahedron Letters, 2017, 58, 3887
DOI: 10.1016/j.tetlet.2017.08.071

A novel two-photon fluorescent probe with long-wavelength emission for monitoring HClO in living cells and tissues

Yi-Jun Gong, Meng-Ke Lv, Ming-Lu Zhang, Zhen-Zhen Kong and Guo-Jiang Mao

Talanta, 2019, 192, 128
DOI: 10.1016/j.talanta.2018.08.089

Ratiometric and colorimetric probes with large stokes shift for sensing of exogenous hypochlorite in potato sprouts and industrial effluents

Mohammed A. Assiri, Muhammad Tahir Waseem, Asad Hamad, Muhammad Imran, Umar Farooq and Sohail Anjum Shahzad

Spectrochimica Acta Part A: Molecular and Biomolecular Spectroscopy, 2023, 290, 122298
DOI: 10.1016/j.saa.2022.122298

A Nontoxic, Bio‐friendly, Fluorescent Chemodosimeter for Hypochlorite Detection in Living Cells through the Oxidation of Hypochlorite on a Hydrazide System

Dibyendu Sain, Abhishek Manna, Chanda Kumari, Chitrangada Das Mukhopadhyay and Shyamaprosad Goswami

ChemistrySelect, 2018, 3, 12050
DOI: 10.1002/slct.201802315

A diketopyrrolopyrrole-based hybrid organic nanoprobe for ratiometric imaging of endogenous hypochlorite in live cells

Kaixuan Nie, Yufeng Yuan, Xiao Peng, Jun Song and Junle Qu

Sensors and Actuators B: Chemical, 2020, 307, 127632
DOI: 10.1016/j.snb.2019.127632

Aggregation-induced emission enhancement (AIEE)-active donor-acceptor type fluorophores based on the 1,3-diaryl pyrazole unit: Conspicuous mechanochromic fluorescence and biosensing of iodide ions

Hai-feng He, Ting Li, Li-feng Yao, Meng-jiao Liu, Hong-ying Xia and Liang Shen

Dyes and Pigments, 2022, 203, 110309
DOI: 10.1016/j.dyepig.2022.110309

A fluorometric and mitochondrion-targetable probe for rapid, naked-eye test of hypochlorite in real samples

Ying Xia, Xiaoyu Liu, Dan Wang, Zechen Wang, Qiang Liu, Haibo Yu, Mingyan Zhang and Youtao Song

Chinese Chemical Letters, 2018, 29, 1517
DOI: 10.1016/j.cclet.2018.01.054

Self-Assembled Triphenylphosphonium-Conjugated Dicyanostilbene Nanoparticles and Their Fluorescence Probes for Reactive Oxygen Species

Wonjin Choi, Na Young Lim, Heekyoung Choi, Moo Lyong Seo, Junho Ahn and Jong Hwa Jung

Nanomaterials, 2018, 8, 1034
DOI: 10.3390/nano8121034