Issue 46, 2018

Controlled synthesis of Fe3O4@ZIF-8 nanoparticles for drug delivery

Abstract

Encapsulating well-defined nanoparticles (NPs) into ZIF-8 to form core–shell structures not only can minimize the drawbacks and maximize the advantages of the disparate components but also may provide synergistic functionality. This work presents novel one-pot synthetic methods to produce Fe3O4@ZIF-8 NPs. Moreover, the morphology of Fe3O4@ZIF-8 NPs can be easily controlled by changing the synthesis conditions (time, temperature, and dosage). The as-obtained Fe3O4@ZIF-8 NPs have good dispersibility and a large specific surface area and they are proven to have potential applications as drug delivery models with good biocompatibility, high drug loading and good pH responsiveness.

Graphical abstract: Controlled synthesis of Fe3O4@ZIF-8 nanoparticles for drug delivery

Supplementary files

Article information

Article type
Paper
Submitted
04 aug 2018
Accepted
08 okt 2018
First published
09 okt 2018

CrystEngComm, 2018,20, 7486-7491

Controlled synthesis of Fe3O4@ZIF-8 nanoparticles for drug delivery

G. Chen, B. Yu, C. Lu, H. Zhang, Y. Shen and H. Cong, CrystEngComm, 2018, 20, 7486 DOI: 10.1039/C8CE01302K

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