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DOI: 10.1039/A606104D (Paper) Reference Section for: J. Chem. Soc., Perkin Trans. 1, 1997, 625-628

Synthesis of (2R)-2-bromodehydroquinic acid and (2R)-2-fluorodehydroquinic acid[hair space]

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Michael K. Manthey, Concepción González-Bello and Chris Abell[hair space]

Abstract

(2R)-2-Bromodehydroquinic acid and (2R)-2-fluorodehydroquinic acid[hair space]† have each been synthesised in six steps from quinic acid via the common intermediate 6. The syntheses exploit the selective protection of the 4-hydroxy group of the quinic acid lactone 3 with tert-butyldimethylsilyl chloride.

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