A new synthetic approach towards trifluoromethylated heterocycles, based on the reaction of 5-acylated N-fluoroalkyl substituted 1,2,3-triazoles under microwave heating, proceeding via ketenimines is presented.
An NHC-catalyzed [3 + 2 + 1] annulation of vinyl azides, aldehydes, and Togni’s reagents was reported. The cascade involves NHC-catalyzed SET redox transformation, denitrogenated radical migration, C–N radical coupling, and defluorinated cyclization.
An unprecedented catalytic carboxylative sulfonylation of propargyl amines with CO2 and sodium arylsulfinates under blue light irradiation with tandem double bond isomerisation at room temperature gives sulfonylated 2-oxazolidinones and 2-oxazinones.
A series of bio-benzoxazine resins based on natural renewable isoliquiritigenin have been designed and synthesized, and their corresponding thermosets exhibit outstanding thermal stability.
This review has been centralized on applications of phthalic anhydride (PA) as a valuable and significant heterocyclic substrate in two- and multicomponent organic reactions.