A facile and environmentally friendly method for synthesizing a range of palladium-N-heterocyclic carbene (NHC) complexes—[Pd(NHC)(η3-R-allyl)Cl]—is described. This permits the testing of their anti-cancer activity.
25 Years after the discovery of the most influential NHC ligand, we revisit and highlight studies involving IPr that have shaped the field of NHC-transition metal catalysis.
The palladium-catalyzed cross-coupling of (E)-2-fluoroallyl carbonates and allylboronates is reported.
We report novel N-heterocyclic carbene (NHC) ligands with N,C/S,C-chelating thiazole donors that have been structurally and electronically characterized. These ligands show potential for coordination and catalysis studies with various metals.
We report a new class of sterically-unsymmetrical NHC ligands. The evaluation of steric, electronic properties and coordination chemistry is described. Studies of catalytic activity in Ag, Pd and Rh-catalyzed reactions are presented.