A sequential three-component intermolecular carbopalladation/Heck cyclization/intermolecular C–H bond functionalization for versatile alkylated polyfluoroarenes containing an indene skeleton is presented.
This review aims to collect advancements in enantioselective palladium-catalyzed cyclization reactions over the past eleven years, and it is organized into thirteen sections depending on the different types of transformations involved.
A straightforward approach for the preparation of fused isoquinolinone derivatives via palladium-catalyzed cascade decarboxylative cyclization of alkyne-tethered aryl iodides with o-bromobenzoic acids is described.
A palladium-catalyzed divergent three-component reaction employing norbornene derivatives as controlled switches toward phosphonate-containing indenes and indanes (and bis-alkylphosphonate functionalized diindane scaffolds) was established.
Divergent synthesis of spirooxindoles and furan-containing oxindoles via base-controlled palladium catalysis was achieved. The key intermediates, allene insertion, and Pd–carbene migratory insertion are supported by DFT calculations.