Mamuna Mukhtar, Haris Ahmed Khan and Najam us Sahar Sadaf Zaidi
RSC Adv., 2023,13, 18306-18322
From themed collection:
2023 RSC Advances Popular Advances Collection
Abstract
Graphical abstract of the study scheme indicatig Nigella sativa's promising inhibition of dengue virus enzymes.
Lok Wan Ng, Yuen-Kit Cheng, Wei Shen Aik and Wei Han
Phys. Chem. Chem. Phys., 2025,27, 12738-12751
Abstract
Reposition pathways of GTP in orthoflavivirus NS5-methyltransferase (MTase) relevant to the N7-MTase reaction have been modelled by two-stage enhanced molecular dynamics simulations.
Wen-Chao Tu, Yong-Xiang Huang, Yuan-Lin Kong, Bo Li, Bin-Bao Wang, Tian-Hao Dong, Wei-Chi Chen, Muhammad Aurang Zeb, Xiao-Li Li, Mei-Feng Liu, Chang-Bo Zheng and Wei-Lie Xiao
Org. Chem. Front., 2024,11, 3614-3623
Abstract
Six dioxygen-bridged abietane-type diterpenoid dimers with unprecedented angular fused and rare parallel fused structures were isolated from Orthosiphon wulfenioides. Notably, compounds 5 and 6 showed potent activity against ZIKV by inhibiting the expression of the E and NS5 protein.
Adam Roberts, Dushanth Seevaratnam, Ferguie B. Solis, Maria Rhona G. Bergantin, Dharmatov Rahula B. Albano, Fortunato B. Sevilla and Elizabeth A. H. Hall
Anal. Methods, 2025,17, 8489-8501
From themed collection:
Analytical methods for a low resource world
Abstract
Recombinant local-production of innovative silica bound RT-LAMP enzymes, extends shelf-life for use in endemic Dengue diagnostic, using novel DENV-1 primer-set.
Irene Georgiou, Colin Robinson, Sean N. O'Byrne, Alex Matsuda, Przemysław Grygier, Craig D. Smith, Sandra O'Neill, Shamshad A. Ahmad, Suzanne Norval, John M. Post, Mirjam Groenewold, Nadya Urakova, Patrick Wanningen, Leanid Kresik, Jacek Plewka, Adrien Delpal, Kexin See, Thomas Eadsforth, Kinga Wierzbicka, Etienne Decroly, Kumar Singh Saikatendu, Edcon Chang, Eric J. Snijder, Krzysztof Pyrć, Anna Czarna, Duncan E. Scott and Ian H. Gilbert
RSC Med. Chem., 2026, Advance Article
Abstract
SARS-CoV-2 non-structural protein 14 (nsp14) is essential for viral mRNA cap guanine-N7 methylation and represents a promising but underexplored antiviral target.