The synthesis of pyrrole-fused heterocycles is demonstrated using the first biomass-derived glucose-mediated one-pot multicomponent nitro reductive cyclization method.
This study describes an efficient and green approach for the synthesis of potentially bioactive pyrrolo[1,2-a]quinoxalin-4(5H)-ones with appreciable functional group tolerance and a wide substrate scope.
In this review, we have summarized the recent progress in two-component and three-component synthetic approaches for the eco-friendly construction of functionalised and fused quinoxaline frameworks.
Pyrroles and their fused compounds are widely known as biologically active scaffolds, which are mainly fused at the 1–2 (a), 2–3 (b), 3–4 (c) and 4–5 (d) positions.
We report an unexpected route for synthesizing pyrrole-fused dibenzoxazepines/thiazepines with high chemoselectivity via a pseudo-Joullié–Ugi reaction from cyclic imines with isocyanides and acetylenedicarboxylates under catalyst-free conditions.