Mechanism, regioselectivity and stereoselectivity of NHC-catalyzed [12+2] annulation of 5H-benzo[a]-pyrrolizine-3-carbaldehydes and cyclic sulfonic imines: a DFT study

Yanlong Kang, Yan Li and Zhiqiang Zhang

New J. Chem., 2025, 49, 15623
DOI: 10.1039/D5NJ02133B

N-heterocyclic carbene-catalyzed enantioselective synthesis of spirocyclic ketones bearing gem-difluoromethylenes

Zheng Liang, Jibin Li, Chaolei Liu, Yiwei Zhu and Ding Du

Org. Chem. Front., 2023, 10, 3027
DOI: 10.1039/D3QO00503H

Substrate-directed divergent annulations of sulfur ylides: synthesis of functionalized bispirocyclopentane and bispirocyclopropane derivatives

Siyi Chen, Peiyao Liang, Yilin Cai, Liejin Zhou and Shoulei Wang

Org. Biomol. Chem., 2024, 22, 2197
DOI: 10.1039/D4OB00146J

Recent advances in the organocatalytic synthesis of chiral C3-spiro-cyclopentaneoxindoles

Yan-Qing Liu, Yan Wu, Bin Li, Xue Tang and Chu Chen

Org. Biomol. Chem., 2025, 23, 757
DOI: 10.1039/D4OB01773K

Mechanisms and regio- and stereoselectivities in NHC-catalyzed [3+3] annulations for the synthesis of axially and centrally chiral dihydropyridinones

Yanlong Kang, Mingchao Zhang, Yan Li and Zhiqiang Zhang

Phys. Chem. Chem. Phys., 2026, 28, 730
DOI: 10.1039/D5CP03567H

N-heterocyclic carbene-catalyzed direct enantioselective synthesis of dihydroisoxazolo[5,4-b]pyridin-6-ones

Xiaoxia Huang, Yarui Li, Jieyin He, Shiyong Peng, Jian Wang and Ming Lang

Org. Chem. Front., 2023, 10, 963
DOI: 10.1039/D2QO01736A

Exploring a general mechanistic map on NHC-catalyzed activation/transformation reactions of saturated carboxylic anhydrides

Shuang-Liang Liu, Yan Qiao and Yang Wang

Org. Chem. Front., 2023, 10, 2670
DOI: 10.1039/D3QO00423F

Atroposelective Access to Dihydropyridinones with C–N Axial and Point Chirality via NHC-Catalyzed [3 + 3] Annulation

Yanting Li, Xiao-Yong Duan, Chengxian Yang, Yamei Wei, Jiahan Li, Xiaojie Ren and Jing Qi

J. Org. Chem., 2023, 88, 11299
DOI: 10.1021/acs.joc.3c00854

Chemodivergent [3+2] and [4+2] Annulations of Isoindigos with Morita–Baylis–Hillman (MBH) Carbonates

Yunping Zheng, Yifan Zhao, Yu Xin, Xiaoxiao Qu, Yushuang Chen, Xiao Xiao, Nianyu Huang and Nengzhong Wang

Org. Lett., 2026, 28, 1661
DOI: 10.1021/acs.orglett.5c05145

N-Heterocyclic Carbene-Catalyzed [3 + 2] Annulation of 3,3′-Bisoxindoles with α-Bromoenals: Enantioselective Construction of Contiguous Quaternary Stereocenters

Binghao Liu, Xiao-Yong Duan, Jiahan Li, Yatong Wu, Yanting Li and Jing Qi

Org. Lett., 2022, 24, 5929
DOI: 10.1021/acs.orglett.2c02180

Stereodivergent construction of [6.5]-spirocycles bearing three contiguous stereogenic centers by Pd-catalyzed [4+2] annulations

Zhan-Cai Ma, Lin-Wen Wei, Song Liu and Yuan Huang

Chem Catalysis, 2023, 3, 100669
DOI: 10.1016/j.checat.2023.100669

Diastereo- and Enantioselective Chemodivergent Three-Component Cascade Reactions via Gold and Carbene Sequential Catalysis

Shulei Zhang, Shao-Jie Wang, Xiaolan Xin, Xia Wang, Zhifeng Tu and Shenci Lu

ACS Catal., 2024, 14, 9275
DOI: 10.1021/acscatal.4c02157

The NHC-Catalyzed Enantio- and Diastereoselective [2 + 3] Annulation of Phthalide-Derived Alkenes with Enal Access to Bispiroheterocyclic Compounds Bearing Three Vicinal Stereogenic Centers

Shao-Jie Wang, Jiayi Hu, Hao An, Man-Yi Han, Xianqiang Kong, Zhifeng Tu and Shenci Lu

Org. Lett., 2025, 27, 6355
DOI: 10.1021/acs.orglett.5c01539

Chiral Phosphine Ligands of COAP and SKP Switched Regiodivergent Asymmetric Allylic Alkylation of MBH Adducts

Xing-Yun Sun, Jia-Yu Song, Bai-Lin Wang, Sheng-Suo Zhou, Zhi-Xiong Ou, Li-Bo Li, Zheng Wang and Xing-Wang Wang

J. Org. Chem., 2024, 89, 4904
DOI: 10.1021/acs.joc.4c00118

Recent Advances in Nucleophilic Lewis Base‐Catalyzed Cycloadditions for Synthesis of Spirooxindoles

Qing‐Feng Li, Jing Ma, Junjia Meng and Er‐Qing Li

Adv Synth Catal, 2023, 365, 4412
DOI: 10.1002/adsc.202300899

Organocatalytic syn-Selective [3 + 2]/[4 + 2] Annulations of (E)-Pyrazoloneyldiene Oxindole

Jialiang Qin, Yuzhen Chen, Wenhong Suo, Xiaodong Han, Weihong Liang, Huicai Huang and Bo Liu

Org. Lett., 2025, 27, 12070
DOI: 10.1021/acs.orglett.5c03738

Convenient Synthesis of Dihydrobenzofuran‐Fused Spirocyclopentane‐1,2‐Diindolinone Scaffolds

Ting Tang, Ying Han, Chao‐Guo Yan, Kun Huang and Jing Sun

Eur J Org Chem, 2024, 27
DOI: 10.1002/ejoc.202400777

Synthesis of Trifluoromethylated γ-Lactams through Radical Cascades of N-Cyano Alkenes with CF3SO2Na

Jianchao Cui, Ye Tong and Yi Li

J. Org. Chem., 2022, 87, 16090
DOI: 10.1021/acs.joc.2c01775