Recent advancements in research on halogen atom transfer (XAT)-driven carbon radical chemistry for organohalides from the perspective of various relayed radicals such as aryl, alkyl, silyl, and boryl radicals are discussed.
A DFT study of Lb–BH2+-mediated C–I activation, Lb–BH2˙-facilitated XAT and alkyl radical generation, and [Cu(II)]-mediated C–N bond formation through combined one-electron oxidation and two-electron reduction.
A visible light-induced organophotocatalytic strategy for dehalogenative deuteration of a wide variety of primary, secondary, and tertiary alkyl bromides is reported.
Direct functionalization of unactivated alkenes via visible-light photocatalysis has emerged as a highly effective strategy for the rapid construction of multi-functional, complex molecular architectures from simple, abundant chemicals.
In this review, photoinduced activation of unactivated alkyl chlorides via single electron transfer strategy, chlorine atom transfer, metallaphotoredox synergistic catalysis, and photoexcited metal catalysis strategies have been discussed.