Terungwa H. Iorkula, Osasere Jude-Kelly Osayawe, Daniel A. Odogwu, Latifat Oluwatobi Ganiyu, Emmanuel Faderin, Raymond Femi Awoyemi, Busayo Odunayo Akodu, Ikhazuagbe Hilary Ifijen, Omowunmi Rebecca Aworinde, Peter Agyemang and Odo Lovelyn Onyinyechi
RSC Adv., 2025,15, 3756-3828
From themed collection:
2025 Reviews in RSC Advances
Abstract
Pyrazolo[1,5-a]pyrimidines are a notable class of heterocyclic compounds with potent protein kinase inhibitor (PKI) activity, playing a critical role in targeted cancer therapy.
Ani Deepthi, Sruthi Sudheendran Leena and Devika Krishnan
Org. Biomol. Chem., 2024,22, 5676-5717
Abstract
The major synthetic routes for thiopyran-fused heterocycles published in the period 2013–2024 have been reviewed.
Louise F. Dow, Alfie M. Case, Megan P. Paustian, Braeden R. Pinkerton, Princess Simeon and Paul C. Trippier
RSC Med. Chem., 2023,14, 2206-2230
Abstract
Enzyme activation is an emerging mechanism of action for new therapeutic discovery, its evolution and application is reviewed herein.
Marian W. Aziz, Khaled O. Mohamed, Amira Karam Khalifa, Doaa B. Farag and Zeinab Mahmoud
RSC Med. Chem., 2025,16, 4220-4238
Abstract
Two novel series of pyridazin-3-ones, designed as potential vasodilators, demonstrated superior aortic vasorelaxant activity, eNOS mRNA expression and nitric oxide up-levelling.
Mrittika Mohar, Tanmay Das and Alakananda Hajra
Org. Biomol. Chem., 2026, Advance Article
Abstract
This review comprehensively summarizes the key advancements in the synthesis and application of oxaborole derivatives over the last decade.