Cell dynamics and metabolism of the foreign body response: characterizing host-biomaterial interactions for next-generation medical implant biocompatibility

Neal I. Callaghan, Christian N. Rempe, Zachary S. C. S. Froom, Kyle T. Medd and Locke Davenport Huyer

Mater. Adv., 2024, 5, 6719
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Bioactive aligned PCL/CQD/Moringa nanofiber conduits accelerate peripheral nerve regeneration: in vitro and in vivo breakthroughs in sciatic nerve repair

Samira Shariati Najafabadi, Mohsen Shie Karizmeh, Mohammad Rafienia, Mohammad Kazemi, Hajar Akbari Dastjerdi, Hamid Bahramian, Seyed Ali Poursamar, Parham Reisi, Azadeh Safaee, Noushin Amirpour and Hossein Salehi

Biomater. Sci., 2025, 13, 5071
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Emerging fiber-based neural interfaces with conductive composites

Chihyeong Won, Sungjoon Cho, Kyung-In Jang, Jang-Ung Park, Jeong Ho Cho and Taeyoon Lee

Mater. Horiz., 2025, 12, 4545
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Fibrous capsule-resistant, controllably degradable and functionalizable zwitterion-albumin hybrid hydrogels

Zuolong Liu, Xianchi Zhou, Yongcheng Chen, Yanwen Ni, Zihao Zhu, Wenzhong Cao, Kexin Chen, Yu Yan, Jian Ji and Peng Zhang

Biomater. Sci., 2024, 12, 468
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Materials Strategies to Overcome the Foreign Body Response

Xianchi Zhou, Youxiang Wang, Jian Ji and Peng Zhang

Adv Healthcare Materials, 2024, 13
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Toward Sex-Specific Biomaterials Innovation: A Perspective

Gerry L. Koons

ACS Biomater. Sci. Eng., 2025, 11, 5131
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The Mechanism of Simvastatin-Mediated M1 Macrophage Polarization Contributing to Osteogenesis and Angiogenesis

Siyu Zhu, Yunmeng Tong, Jiaqian Huang, Yuzhu He, Wenqi Fu, Yaran Zang and Huiying Liu

Biomedicines, 2025, 13, 1454
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A Small-Diameter Artificial Vascular Graft: Biocompatibility Evaluation and Regulatory Mechanisms of Vascular Remodeling at the Cellular and Molecular Levels

Zhenhao Zhang, Shuo Wang, Jiafei Li, Ge Tian, T. A. M. In Pan, Yunhui Lv, M. A. Chi Yung, Peng Peng, Xuemin Wang, Xiaodong Hao, Qi Zhang, Jiafei Luo, Xue Zhang, Peihe Wang, Junying Fan, Chen Shen, Jinyan Zhu and Yongchun Cui

ACS Appl. Bio Mater., 2025, 8, 7925
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Immunoengineering Biomaterials for Musculoskeletal Tissue Repair across Lifespan

Jin Han, Alexandra N. Rindone and Jennifer H. Elisseeff

Advanced Materials, 2024, 36
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Cross‐Linked Zwitterionic Surface Modifications for Biocompatible Blood‐Contacting Medical Devices

Matthew Crago, Kieran Lau, Silas Qian, Richard P. Tan, Juichien Hung, Behnam Akhavan, Marcela M. Bilek, Fariba Dehghani, Steven G. Wise, Sepehr Talebian and Sina Naficy

Adv Healthcare Materials, 2026, 15
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Murine gut microbiota dysbiosis via enteric infection modulates the foreign body response to a distal biomaterial implant

Brenda Yang, Natalie Rutkowski, Anna Ruta, Elise Gray-Gaillard, David R. Maestas, Sean H. Kelly, Kavita Krishnan, Xinqun Wu, Shaoguang Wu, Allen Chen, Joscelyn C. Mejías, Joshua S. T. Hooks, Isabel Vanderzee, Patricia Mensah, Nazmiye Celik, Marie Eric, Peter Abraham, Ada Tam, Franck Housseau, Drew M. Pardoll, Cynthia L. Sears and Jennifer H. Elisseeff

Proc. Natl. Acad. Sci. U.S.A., 2025, 122
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Crosstalk between T cells and fibroblasts in biomaterial-mediated fibrosis

Mathew Kibet and Daniel Abebayehu

Matrix Biology Plus, 2025, 26, 100172
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Poly(Glutamic Acid‐Lysine) Hydrogels with Alternating Sequence Resist the Foreign Body Response in Rodents and Non‐Human Primates

Xianchi Zhou, Wenzhong Cao, Yongcheng Chen, Zihao Zhu, Yifeng Chen, Yanwen Ni, Zuolong Liu, Fan Jia, Zhouyu Lu, Yang Ye, Haijie Han, Ke Yao, Weifeng Liu, Xinyue Wei, Shengfu Chen, Youxiang Wang, Jian Ji and Peng Zhang

Advanced Science, 2024, 11
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The advances in zwitterionic materials and their biomedical applications

Wei He, Jiayao Wen, Qiaoying Hu, Yanmin Yi, Zhijian Wei, Xiaoye Yang, Guangxi Zhai, Feng Li and Lei Ye

International Materials Reviews, 2025, 70, 301
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Editorial: Modulation of the Immune System to Improve Tissue Regeneration Strategies

Laura G. Bracaglia and Themis R. Kyriakides

Tissue Engineering Part A, 2024, 30, 257
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Biological Responses to Biomaterials: Mechanisms and Opportunities for Enhanced Oral Tissue Regeneration

Yinghong Zhou, Tian Xu, Pingping Han, Cong Wang, Mark Bartold and Sašo Ivanovski

J of Periodontal Research, 2026
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Bioinspired approaches to encapsulate and deliver bacterial live biotherapeutic products

Noah Y. Brittain and Joel A. Finbloom

Advanced Drug Delivery Reviews, 2025, 225, 115663
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Mechanotherapy: Modulating immune cell function in tissue regeneration and fibrosis

Niamh A. Ward, Hannah Prendeville, Eimear J. Wallace, Parand Shokrani, Lesley Trask, Rachael Dillon, Rachel Beatty, Ellen T. Roche, Garry P. Duffy and Eimear B. Dolan

Acta Biomaterialia, 2025, 205, 34
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Antigen-conjugated scaffolds enable sustained delivery of antigen and enrichment of antigen-specific T-cells

Sydney N. Wheeler, Mary E. Dickenson, Connor N. Joyce, Samantha N. Lukpat, Leon J.M.W. Wagner, Andrés R. Muñoz-Rojas and Aaron H. Morris

Journal of Controlled Release, 2026, 390, 114564
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The nude rat is capable of mounting a strong fibrotic response against cell-containing and cell-free subcutaneously implanted encapsulation devices

Kelly M. Pasowisty, Amy C. Kelly, Trisha M. Fabijanic, Leah V. Steyn, Hannah A. Hagen, Thomas Loudovaris, Robert C. Johnson, Charles W. Putnam and Klearchos K. Papas

Cell Transplant, 2026, 35
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Profiling Pro‐Inflammatory Proteases as Biomolecular Signatures of Material‐Induced Subcutaneous Host Response in Immuno‐Competent Mice

Nam M.P. Tran, Anh T.H. Truong, Dang T. Nguyen and Tram T. Dang

Advanced Science, 2025, 12
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Bone Grafts: Everything You Need to Know

Håvard Jostein Haugen, Javier Sanz, Giuseppe Perale, Augustine Mark Saiz, Mario Romandini and Maryam Rahmati

J of Periodontal Research, 2026
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Diminished fibrotic encapsulation and comparable physicochemical properties of poly (styrene-b-isobutylene-b-styrene) support its use as a biomaterial alternative to silicone implants

Nikita Kalashnikov, Leonard Pinchuk and Joshua Vorstenbosch

Front. Bioeng. Biotechnol., 2026, 14
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Decoding fibrotic encapsulation in plastic surgery implants: From biological mechanisms to precision interventions frontiers

Jiaqi Liu, Biqing Chen and Ik Yang

Colloids and Surfaces B: Biointerfaces, 2026, 257, 115191
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