Issue 1, 2022

Competitive gold/nickel transmetalation

Abstract

Transmetalation is a key method for the construction of element–element bonds. Here, we disclose the reactivity of [NiII(Ar)(I)(diphosphine)] compounds with arylgold(I) transmetalating agents, which is directly relevant to cross-coupling catalysis. Both aryl-for-iodide and unexpected aryl-for-aryl transmetalation are witnessed. Despite the strong driving force expected for Au–I bond formation, aryl scrambling can occur during transmetalation and may complicate the outcomes of attempted catalytic cross-coupling reactions.

Graphical abstract: Competitive gold/nickel transmetalation

Supplementary files

Article information

Article type
Communication
Submitted
27 oct. 2021
Accepted
26 nov. 2021
First published
26 nov. 2021

Chem. Commun., 2022,58, 68-71

Competitive gold/nickel transmetalation

M. J. Demchuk, J. A. Zurakowski, B. J. H. Austen, D. J. Nelson and M. W. Drover, Chem. Commun., 2022, 58, 68 DOI: 10.1039/D1CC06064C

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